Insights On Outsourced Drug Development
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Expansion Of MRC-5 Cells On Microcarriers Via Serial Passage In Stirred Vessels
9/1/2022
In this application note we characterize MRC-5 cell growth on multiple microcarriers in stirred vessels and present data demonstrating feasibility of serial passage and scale-up into bioreactor expansion of MRC-5 cells.
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The Journey To AAV Production In Suspension – Scaling-Up Your Process
9/27/2022
We present a simple protocol for scaling up AAV production using HEK293 host cells cultured in suspension and under serum-free conditions.
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Streamlining 3D Cancer Assays With Automated Innovations
5/13/2024
This article discusses the use of 3D cultured cancer models in the search for new therapies for complex diseases like cancer.
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Advancing 3D Cell Culture Models For Clinical Relevance
4/9/2024
Concerns about in vitro relevance and animal study limits have advanced cell culture tech. Explore how Organ-Chips offer a refined approach to studying human physiology.
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A Micronization Method Enabling The Formulation Of Biopharmaceuticals
6/29/2023
Micronization is key for increasing the loading efficiency and lowering the burst of microspheres. Applying lyophilization-based micronization methodology at a small scale helps to support challenging formulation development projects.
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Liquids, Soft Foods As Vehicles For Enteric Coated Bead Drug Product
4/10/2024
Take a deeper look at the challenges and solutions involved in creating a child-friendly medication delivery system, and learn about the importance of collaboration and meticulous scientific processes.
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Innovation Standardized – Bioseparation Methods For Biotherapeutics
7/5/2022
Discover the most impactful standards in liquid chromatography (LC) for biotherapeutics. The standardizations include methods, columns, standards, and robustness.
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Microcarrier-Based Production Of Dengue Virus In An Optimized Animal-Free Virus Production Medium
8/31/2022
The use of undefined components in animal product-free (APF) cell culture media is one source of variability in cell culture processes. Explore how microcarriers provide an economical and robust platform for vaccine production using adherent cell types.
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A Pharmaceutical Perspective On Generating And Utilizing Multiomic Data
4/17/2024
Ratnakar Potla of Genentech explains how Organ-Chips enable scientists to obtain a wider variety of multiomics data to better understand biological processes.
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The Application Of The Species-Specific Liver-Chip In Predicting Hepatoxicity
3/13/2024
An evaluation of 150 drug candidates causing adverse events in humans revealed testing in rats and dogs predicted only 71% of toxicities in humans. Discover a solution to this translational challenge.