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Advanced Science And The Art Of Letting Go: Considerations In Transferring Cytometric Assays From The Bench To A Central Laboratory
March 4, 2008
•Article: Advanced Science And The Art Of Letting Go: Considerations In Transferring Cytometric Assays From The Bench To A Central Laboratory
Written and compiled by Carol Rosenthal MS, Director of the Cellular Immunology Labs, ICON Central Labs and Michael Rozenzweig BVSc, PHD, Director of Preclinical Development, Tolerx Inc.
Flow cytometry is an emerging technology used for the separation, classification, and quantitation of blood cells. The science of cytometry has been in existence since 1969, and instruments were often found in the back corners of biotech and university research laboratories. Over the past decade, we've seen the technology come into use in a clinical lab setting, and it now plays a key role in monitoring the immune system. Since a large percentage of the next generation of therapeutics is biologically active molecules already existing within the human system, many treatments are directing the immune system to restore human health. The modality of these compounds is often to up-regulate or down-regulate the immune system by targeting certain cells, blocking signals, reducing inflammation, and altering communication pathways among blood cells.
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