Articles
Aqueous Critical Cleaning In Pharmaceutical Manufacturing
May 12, 2008
•White Paper: Aqueous Critical Cleaning In Pharmaceutical Manufacturing
The benefits of employing aqueous cleaning in pharmaceutical manufacturing are numerous. Virtually any pharmaceutical manufacturing equipment from tablet press to a stainless steel mixing tank can achieve their defined critically clean criteria using aqueous cleaning. Typically aqueous cleaners are formulated to ensure maximal cleaning performance by using key ingredients such as surface active agents (surfactants) that are excellent wetting agents that allow the cleaning solution to penetrate into crevices while getting under soils to allow for removal. Often very dilute solutions of aqueous cleaner effectively removes even worst case substances off a variety of hard surfaces including stainless steel, glass, plastic, or porcelain.
The proper use of aqueous cleaning helps manufacturers minimize surface residue and makes cleaning validation easier. Aqueous cleaners are available in low toxicity formulations that make achieving acceptable residue levels easy during cleaning validations. Often even multi-product facilities can find a single aqueous cleaner that cleans all residues on all surfaces. This means less cost for the manufacturer because only one cleaner has to be validated.
Click Here To Download:•White Paper: Aqueous Critical Cleaning In Pharmaceutical Manufacturing
