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03.09.2010 -- Five Essentials For Minimizing Clinical Development Risk And Ensuring Success

March 9, 2010

Pharmaceutical Online Newsletter
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In This Issue:

Featured Articles

What You Don't Know Can Hurt You: Five Essentials For Minimizing Clinical Development Risk And Ensuring Your Greatest Chance Of Success
By HealthDecisions
"The pivotal trial failed," said a senior pharma executive in private conversation. "I got the call on Friday. I was dumbstruck — given its success in earlier work I could hardly believe it." This type of shock is all too typical. Late-stage disappointments in clinical development programs are common, and many times come as a complete surprise to everyone involved.


What Is pH, And How Is It Measured?
By Frederick J. Kohlmann, Hach Company
pH is defined as the negative logarithm of the hydrogen ion concentration. This definition of pH was introduced in 1909 by the Danish biochemist, Soren Peter Lauritz Sorensen.


Contamination Control: Developing A Solid Maintenance Plan With An Industrial Vacuum
Paul Miller, Vice President & General Manager of Nilfisk CFM
In developing a comprehensive and effective cleaning program, pharmaceutical plants should understand the importance of choosing the correct vacuum for their application — this machinery represents a critical component in helping to minimize or avoid certain risks.


Top Five Ways Automation Of Document-Based Processes Can Boost Financial Success
By MasterControl
In today's global market, innovation and business growth are impossible without the aid of technology. While cutting costs and maintaining operational efficiency remain priorities for businesses, most companies understand that technology not only fuels innovation, but it can help drive business growth.


The Potential Of Personalized Medicine
By Cliff Mintz Ph.D., Life Science Leader magazine
Personalized or individualized medicine is the latest life sciences innovation that is poised to transform medicine and delivery of healthcare to patients. While some describe personalized medicine as a technology of the future, others contend that personalized medicine is already influencing and having an impact on the way patients are being treated today.

Sponsor

The March 2010 digital edition of Life Science Leader is now available!

The March 2010 digital edition of Life Science Leader is now available!

Here are just a few of the highlights:

  • Double-Digit Growth: The Next Step For Dr. Reddy's
  • The UK Biopharm Industry: Promoting Industry And Innovation
  • How Technology Will Enable Next-Generation Drug Development Practices
If you are interested in any of the advertisers within this issue, just click on the ad to be taken directly to their website. View the March 2010 Issue of Life Science Leader

Spotlight On Tanks And Vessels

Product Sheet: Jacketed Tanks
Our cylindrical jacketed tanks are custom made to satisfy your process, mixing, and temperature control requirements. Built from 304, 304L, 316, or 316L stainless steel, our jacketed tanks can be easily adapted to meet your dimensional requirements. All standard sizes have optional features that allow for made-to-order applications.

INTERPHEX Booth 1141

Product Sheet: Jacketed Tanks

Product Overview: Tote Unloading Systems
The tote unloading system is engineered to efficiently transfer liquid ingredients. The tote feeds into a reservoir; and, from there a pump draws the product and distributes it to one or more usepoints.

Product Overview: Tote Unloading Systems

Product Sheet: G2 Silver Series IBCs
The Silver Series IBC manufactured by G2 is of the highest quality and design available for the nutraceutical, food, and chemical industries. The product and non-product areas are all T-304 stainless steel. The interior has 2B mil finish with all welds wire brushed and cleaned.

Product Sheet: G2 Silver Series IBCs

Product Sheet: Typhoon Tank Washers
The Typhoon is designed to be one of the most powerful and versatile tank cleaning machines in its class. The sleek, smooth exterior, combined with the unit's self cleaning abilities, provides an ultra hygienic exterior surface suitable for use in the most hygiene conscious environments.

Product Sheet: Typhoon Tank Washers

Brochure: Stainless Steel Whirly Tank Cleaning Nozzle (Series 569)
The Lechler Stainless Steel Whirly Nozzle is the workhorse of Lechler's tank cleaning product line. Compared to a non-rotating spray ball for which clogged orifices can cause voids in coverage, the free-spinning Whirly Nozzle uses the moving flow of the cleaning fluid, in addition to impact, for its effectiveness.

Brochure: Stainless Steel Whirly Tank Cleaning Nozzle (Series 569)

Featured Downloads

Technical Brochure: 4400C Series — Reverse Osmosis Systems
The Biolab Equipment™ 4400C Series RO machines are designed to produce 2,000 to 30,000 gallons/day of pure water. The 4400C series provides high quality product water, user-friendly controls, durable construction, and easy installation.

White Paper: The Green, Clean, And Lean Approach To Cleaning API Equipment
Traditional Clean-in-Place (CIP) technology has its shortcomings: it is labor intensive, results in unproductive downtime, and often wastes resources. For many industries, traditional CIP methods remain unable to respond to their necessary cleaning needs and requirements.

Case Study: Quadro FlexSift
Benefits noted in this study include the fact that the Quadro FlexSift is more compact than the other two technologies and easier to assemble. The Quadro FlexSift screen design has fewer components than the Horizontal Centrifugal Sifter or a Vibratory Sifter. While the capacity of the Quadro FlexSift is higher than that of the Vibratory or Horizontal Centrifugal Sifters, the torque and sifting forces on the equipment are much less than the other two sifting technologies.

Brochure: Custom Solutions For The Pharma Biotech Industry
The Industrial Business of Roche Applied Science provides a broad range of products and services to support the diagnostics, life science, pharmaceutical, and biotech industries.
Browse the download library

Industry News

Merck Speaks Out On Vioxx® Judgment In Australia
The False Claims Act Empowers Citizens And Law Firms To Fight Fraud
NextPharma Announces 2.4 Million Investment To Upgrade Its Sterile Vial Area At Belgian Facility
RECENTIN Did Not Meet Primary Endpoint In Horizon III Study In Metastatic Colorectal Cancer
Kendle Receives Approval From To Proceed With Development Of Operations Center In India
Quintiles Extends Phase I Capacity And Capabilities
Azopharma Product Development Group Refocuses And Restructures
Roche And Biogen Idec Decide To Suspend Ocrelizumab Treatment
BioTek's Synergy H4™ Hybrid Reader Is LanthaScreen® Plus Certified
GAMP® Good Practice Guide: Manufacturing Execution Systems Guide Now Available
Vortex® Valves International Opens Office In Switzerland
Eurand Reports Recent Developments
Rexahn Pharmaceuticals Issued Japanese Patent For Anticancer Compound Archexin
Porvair Filtration Group Introduces Pharmaceutical Membrane Filter Validation Guide
Quantos Wins The R&D 100 Award
View more headlines

Featured Multimedia

Video: G2's Latest Containment Project
Video: G2's Latest Containment Project
G2's latest containment project: IBCs were loaded above the tablet press and discharged using buck split butterfly valves.

Bulletin Board

Guide: Personnel And Product Protection — A Guide To Biosafety Enclosures
Guide: Personnel And Product Protection — A Guide To Biosafety Enclosures
This booklet was developed as a guide to selecting a biosafety enclosure that provides personnel and/or product protection. The information presented is unbiased and generic in nature, and compiled with help from experienced microbiologists, engineers, and safety enclosure users.

Industry Event

INTERPHEX
April 20 to 22 | New York, NY

Training

Featured Courses From The Center For Professional Innovation And Education

Project Management For The Phase 3 And LCM (Life Cycle Management) Of The Drug Development Process
April 12 and 13 | Dublin, Ireland

How To Monitor Clinical Trials For GCP Compliance
April 12 and 13 | King of Prussia, PA

Best Practices For Facilities And Utilities Design, Qualification, And Monitoring: Applying The Life-Cycle Concept
April 12 and 13 | King of Prussia, PA

Effective Qualification And Monitoring Of Processing Equipment And Their Control Systems
April 14 and 15 | King of Prussia, PA

Detecting Fraud And Misconduct In Clinical Trials
April 14 and 15 | King of Prussia, PA

Pediatric Clinical Trial Design: Ethics, Management, And Regulatory Requirements
April 20 and 21 | King of Prussia, PA

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