Articles
Flexible Solutions Broaden Containment Options By Alan E. George, ILC Dover
February 27, 2007
•Flexible Solutions Broaden Containment Options
With the ever-increasing demand for advanced powder containment solutions, flexible containment options and hybrid flexible/rigid solutions are offering process engineers more choices than ever before.
The basic containment goals to be reached center around affording the operator the optimum protection based on the containment band for the product being processed, maintaining good cGMP conditions, eliminating cross contamination, and reducing cleanup requirements.
Historically, stainless and glass isolators and cross flow booths were the systems of choice for active pharmaceutical powder containment. Containment by isolation solutions involves total process isolation; and, thereby, effectively shields the operator and the remaining process train from powder transfer operations. Although these solutions are acceptable for new construction, they often are challenging to implement in a retrofit situation due to space and process flow considerations.
Alan E. George is the Pharmaceutical Product Line Manager for ILC Dover's
Containment Products. He is actively involved in developing applications of
flexible containment for various types of process equipment by working directly
with pharmaceutical manufacturers and ILC's engineering staff. These designs
are then manufactured by ILC to support the production of potent compounds.
Mr. George's background over the past 25 years with ILC has ranged from
design through management of programs and the introduction of new products
for both Department of Defense and commercial uses where softgoods are
designed to meet high reliability requirements such as those facing the
pharmaceutical industry today. The designs being implemented are based on
technologies developed through ILC's roles for such products as all of the space
suits used by NASA since Neil Armstrong first walked on the moon, airship and
aerostats envelopes, and the landing impact bags for the Mars Pathfinder
program.
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