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Process Proteomics Explained

April 27, 2007

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Article: Process Proteomics Explained

Proteomics — the measurement and characterization of proteins — has become standard in developing novel protein therapies. Robust, reliable analytical methods for targeting and tracking disparate elements of protein samples and quantifying them in final products are critical to manufacturing biopharmaceuticals. However, current methods are time-consuming and complex. Process proteomics is a new approach to pharmaceutical, vaccine, and diagnostic molecule process development. This integrated technology can significantly reduce biopharmaceutical development times and costs — shortening the period from research laboratory to large-scale production.

Advances in technology to produce protein-based drugs have accelerated the search for novel protein therapeutic candidates. But practical and cost-effective expression of proteins in amounts that allow for their characterization, evaluation, and scale-up to production presents many difficulties.

Reprinted with permission from BioProcess International 4(5):66-67 (May 2006)

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Article: Process Proteomics Explained

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