Articles

Pall Corporation is introducing an enhanced bioburden reduction filter that combines three novel technologies to provide more economical filtration of a broad range of biopharmaceutical fillers and buffers. The Supor® UEAV 0.2 micron filter increases filter service life and protects sterilizing grade filters and other sensitive downstream processing equipment such as tangential flow filtration (TFF) and chromatography systems.

It achieves this by incorporating three advanced technologies into a single filter:

• an asymmetric Supor® mach V membrane structure with controlled pores from three down to 0.2 microns which provides high solids capacity;
  
• the new deep-pleat Ultipleat® construction which provides enhanced surface area of over one m² per 10 inch (254 millimeters) module, resulting in high flow rates and extending solids capacity; and
  
• the Pall polyethersulfone (PES) membrane that ensures excellent chemical compatibility and low nonspecific binding to extend service life.

The new filter's particle removal capability works with a diverse range of biopharmaceutical fluids including buffers, biologicals, tissue culture media, ophthalmics and cell culture supernatants. It is applicable for a broad number of markets including biotechnology, blood products and vaccines. For example, it prolongs the life of sterile filters for fermentation and cell culture harvest and helps to assure low bioburdens prior to sterilizing filtration in final filling of parenterals.

"By expanding the service life of other filters - - and in some cases precluding the need for sterilizing grade filters downstream - - the Supor® UEAV offers a host of benefits in addition to direct cost-savings," says Monica Cardona, Marketing Manager, Pall BioPharmaceuticals. "Its increased surface area meets the need for higher flow rates, and more hold capacity per unit size to extend service life, while also enabling wider use of disposable technologies."

The Supor® UEAV is the newest addition to the Pall Supor® Line of products that incorporates PES media. It is available for use in filter housings and as ready-to-use Kleenpak Nova disposable filter assemblies. PES is one of the Company's fastest growing technologies for the biopharmaceutical market.

Source: Pall Life Sciences

---

• Request Information
• Contact Details
• Company Profile

---