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02.04.2010 -- Today's Issues Of Containment For Solid Dosage Production

February 4, 2010

Pharmaceutical Online Newsletter
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Pall Life Sciences

Pall Life Sciences

The Palltronic® Flowstar IV integrity test instrument is fast, accurate, and designed for use in laboratories or cleanrooms. Offering latest networking and automation options, it is supported by extensive qualification documentation with worldwide technical and after-sales support. For more information, please email flowstar@pall.com

From The Publisher

Welcome back to the Pharmaceutical Online newsletter and our Special Report On Filtration — including information from Mettler-Toledo Thornton, Mar Cor Purification, as well as from one of our newest suppliers, Steris. Find out more about Today's Issues Of Containment For Solid Dosage Production and The Business Benefits Of Calibration, in today's featured articles.

Pharmaceutical Online also invites you to submit your technical articles, application notes, white papers, tutorials, videos, press releases, and other relevant content for featuring on www.pharmaceuticalonline.com and in our e-mail newsletter. To request a copy of our 2010 Editorial Calendar, or to send submissions or questions, e-mail editor@pharmaceuticalonline.com.

John Clifton, Vice President of Publishing, VertMarkets, Inc.

Featured Articles

Today's Issues Of Containment For Solid Dosage Production
By GEA Process Engineering Inc.
When talking today about solid dosage form production, in 9 out of 10 cases containment immediately becomes one of the issues. Why? The first reason is that APIs are becoming more and more potent. The second reason is that health and safety authorities all around the world are putting more focus on the protection of operators dealing with these substances. The third reason is that suppliers of various hardware components have developed a huge variety of containment solutions.


The Use Of Syringe Filters For Analytical Sample Preparation
By Larry Scheer, Pall Life Sciences
Filtration is increasingly used as a protective measure in analytical sample preparation. As a result, there are more filter options to choose from than ever before, and each has its own performance properties.


Noninvasive Delivery Offers Opportunities For Large And Small Pharma
By Edward Maggio, Ph.D., Life Science Leader magazine
Peptide and protein drugs are among the most useful and effective drugs yet discovered, exhibiting potent biological activity, high binding specificity for specific biological targets, and essentially no chemical toxicity with few or no drug interactions. There are more than 140 peptide and protein drugs in current use today, and their number and importance is rapidly increasing.


The Synthesis Of 3-Methyl Salicylic Acid [ring-14C(U)]
By Analytical Bio-Chemistry Laboratories (ABC Labs)
3-Methyl salicylic acid is an important precursor for the synthesis of many biologically active species. For example, Moreau reported the synthesis of a series of aryhydrazones and evaluated their vitro antifungal properties against two human pathogenic yeasts.


The Business Benefits Of Calibration
By Beamex
Calibration can be briefly described as an activity where the instrument being tested is compared to a known reference value. At the simplest level, calibration is a comparison between measurements — one of known magnitude or correctness made or set with one device — and another measurement made in as similar a way as possible with a second device.

Speical Report: Filtration

White Paper: PAT Initiatives And TOC Measurements For Higher Product Quality And Profitability
In recent months, the use of PAT (Process Analytical Technology) terminology has consumed the vocabulary of pharmaceutical professionals. At its core, the PAT initiative is designed to address manufacturing-related quality issues in the pharmaceutical industry by encouraging process innovation.

White Paper: PAT Initiatives And TOC Measurements For Higher Product Quality And Profitability

Brochure: Niro Model M Membrane Filtration Pilot Plant
The GEA Filtration Model M Pilot Plant is a laboratory-scale test plant designed for feasibility testing of cross-flow membrane filtration applications in the microfiltration, ultrafiltration, and nanofiltration ranges.

Brochure: Niro Model M Membrane Filtration Pilot Plant

Brochure: Finn-Aqua BPS Biopharmaceutical Steam Sterilizer (Autoclave)
Finn-Aqua GMP Steam Sterilizers provide shortened validation, increased reliability, and flexibility. Each sterilizer is available with all the standard sterilization processes that utilize steam as the sterilizing agent, including saturated steam, steam-air mix and water-air mix. Customized cycles can also be developed, based on customer-specified requirements.

INTERPHEX Puerto Rico Booth 808

Brochure: Finn-Aqua BPS Biopharmaceutical Steam Sterilizer (Autoclave)

Datasheet: Sartobran® P 0.1 µm Sterilizing Grade Filter Cartridges
Sartobran P 0.1 µm rated, high-flow filter elements are designed to give enhanced sterility assurance for applications with microorganisms present that can pass through 0.2 µm rated sterilizing grade filters.

Datasheet: Sartobran® P 0.1 µm Sterilizing Grade Filter Cartridges

Brochure: FiberFlo Teflon Pleated Cartridge Filters
Containing 8.0 square feet of expanded PTFE membrane, FiberFlo Teflon Filters offer users a highly efficient hydrophobic "barrier", ensuring low moisture content of ultrapure gasses. Additionally, it will ensure filtration performance in the purification of aggressive liquids and organic solvents.

Brochure: FiberFlo Teflon Pleated Cartridge Filters

White Paper: The Need For A Broader Perspective If PAT Implementation Is To Be Successful In The Pharmaceutical Sector
Process analytical technology (PAT) has the potential to deliver significant shifts in the economics of the pharmaceutical sector. In the years since the FDA published its guidance on PAT, there has been a wealth of research and comment articles on its adoption by the industry.

White Paper: The Need For A Broader Perspective If PAT Implementation Is To Be Successful In The Pharmaceutical Sector

Datasheet: Tangential Flow Filtration Systems
Pall offers scalable, predesigned systems to suit your specific process needs. Pall Standard systems are ready-to-use, engineered systems with integrated recipe management tools to expedite your approval processes and reduce your time to market.

Datasheet: Tangential Flow Filtration Systems

Datasheet: Liqui-Flux W03 Water Filtration Product
Liqui-Flux modules are designed to filter surface, brackish, potable, municipal, process water, and water feeding RO desalination systems.

Datasheet: Liqui-Flux W03 Water Filtration Product

Guide: Laboratory Water Purification
Provides an overview to laboratory water purification including water quality standards, contaminants, and purification methods. A glossary of terms is included.

Guide:  Laboratory Water Purification

Industry News

Does Pharma's New Home Lie At The Corner Of Facebook And Twitter?
IATA Chapter 17 Revised Regulations And Biopharma Requirements For Temperature-Sensitive Products Discussion
Poniard Pharmaceuticals To Cut Workforce 57%
Pall Introduces The PallSep Biotech Filtration System For Difficult-To-Process Biotechnology Feed Streams
FDA Approves Xiaflex For Debilitating Hand Condition
Schreiner MediPharm To Introduce Innovative Self-Lifting Label At Interphex 2010
TTP LabTech Launches New High-Content Contract Screening Service
Copley Scientific Launches World's First Commercial Apparatus For Dissolution Testing Of Inhaled Drugs
Billion Dollar Market For Malaria Vaccine Products Should Interest Drug Developers
clinicalprojects International GmbH Announces Further Growth Into New Therapeutic And Geographic Areas
Cymbalta® Significantly Reduced Chronic Low Back Pain In New Study
Teva Announces FDA Accepts BLA For XM02
VaxGen Stockholder Vote Insufficient To Approve Merger With OXiGENE
Daiichi Sankyo Initiates Largest Phase III Trial For Venous Thromboembolism
Mirrx Therapeutics A/S Secures Seed Financing For Development Of Novel MicroRNA-Blocking Technology
View more headlines

Featured Multimedia

Video: Seal-Scan™ 550 For Online Pouch Seal Inspection
Video: Seal-Scan™ 550 For Online Pouch Seal Inspection
Seal-Scan™ 550 for online pouch seal inspection using PTI's patented nondestructive airborne ultrasound technology.

Bulletin Board

Millrock Announces The New Revo Series Freeze Dryer
Millrock Announces The New Revo Series Freeze Dryer
The Millrock Revo Series is a new generation laboratory research shelf freeze dryer. Product can be loaded on the shelves and frozen prior to drying. A rectangular chamber offers a compact profile with either stoppering or bulk assembly.

Industry Events

Meet With Aptuit At Informex 2010
February 16 to 19 | San Francisco, CA

Freeman Technology: Course On Blending And Flow Of Pharmaceutical Powders
February 23 to 25 | Pearl River, NY

Pittcon Conference And Expo 2010
February 28 to March 5 | Orlando, FL

INTERPHEX Puerto Rico
March 4 and 5 | San Juan

Sealing Technology For Packaging Processes
March 10 and 11 | Philadelphia

INTERPHEX
April 20 to 22 | New York, NY

Submission Information

Pharmaceutical Online invites members of the community to submit their technical articles, application notes, white papers, tutorials, videos, press releases, and other relevant content for featuring on www.pharmaceuticalonline.com and in our e-mail newsletter. Please send your submissions or questions to us at editor@pharmaceuticalonline.com.

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