Product/Service
Pallsep Vibrating Membrane Filtration Technology
•Datasheet: Pallsep Vibrating Membrane Filtration Technology
Pallsep filtration technology represents a significant innovation in membrane filtration. In the Pallsep system, controlled horizontal oscillation moves the membrane elements through the feed fluid over 50 times per second. The oscillation generates vibrational energy at the membrane surface, giving shear (higher than that typically generated in conventional TFF systems) that is limited to a small boundary layer above the membrane surface, and which is not applied to the bulk of the fluid. This ensures that even in high solids feed streams, the membranes do not cake with the retained species. Fluids are processed in a very gentle manner through an open flow path with minimal pressure drop and even transmembrane pressure distribution. Very high suspended solids levels can be achieved (> 60% w/v*) maximizing recovery of the permeate. In some applications it is possible to concentrate solids in a single pass with no recirculation. Both the concentrated solids and the filtrate can be recovered from the system if required by the application.
Features and Benefits
- Very low recirculation rates
- Energy efficient
- Tolerant of viscous feeds
- Processing to high suspended solids
- Gentle processing
- Small system footpaint
- Low system hold-up volume
Applications
The technology can be successfully applied to clarification applications where high product transmission through the membrane is essential and not easily achieved with conventional TFF systems, and harvesting applications where product loss with conventional TFF/centrifugation is unacceptably high.
- Recovery of therapeutic proteins from recombinant mycelial cultures
- Clarification of high suspended solids fermentation broths such as Picha pastoris and Saccharomyces
- Processing of plant and animal extracts from transgenic or natural sources * Wet cell weight – see Postlethwaite et al. Journal of Membrane Science 228 (2004), 89 – 101.
•Datasheet: Pallsep Vibrating Membrane Filtration Technology
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