Product/Service
Stax™ Disposable Depth Filter Systems
Brochure: Stax™ Disposable Depth Filter Systems
Article: Evaluation And Implementation Of A Single-Stage Multimedia Harvest Depth Filter For A Large-Scale Antibody Process
Pall's single-use Stax AKS capsules eliminate the use of stainless steel housings which require costly cleaning and cleaning validation. Stax system chassis are designed for assembly and use by a single operator and provide a logically conceived disposable platform in which the operator can load, operate and unload in an ergonomically designed vertical orientation. The Stax platform has been designed to accommodate nearly all processing options such as: bottom up, top down, bottom in/bottom out and in series.
Seitz AKS Filter Media
Macro- and mesopores can generally be regarded as the highways into the carbon particle, and are crucial for adsorption kinetics. Macropores are used for the transport, and absorption occurs in the meso- and micropores. Small molecules, such as methylene blue, which has a molecular weight of 319.86 daltons, are mainly captured in micropores. For larger impurity molecules, other pore structures in the carbon must be available to ensure optimal adsorption. Carbon, which can capture larger molecules, tends to adsorb smaller impurities as well, whereas dedicated carbons for small molecules do not remove larger contaminants.
Highest Efficiency in Adsorption and Design
Powdered activated carbon (PAC) is widely used in the pharmaceutical industry for decolorization and removal of other trace impurities. The use of bulk PAC has significant drawbacks relating to the handling of bulk carbon powder, cleaning of process equipment, and time (costs) associated with carbon removal from the process. Seitz AKS immobilized carbon media alleviates these concerns by incorporating activated carbon within a matrix of cellulosic fibers. This immobilized carbon media is then coupled with a downstream filter paper to prevent carbon particle shedding downstream of the filter. Additionally, the adsorption efficiency of Seitz AKS immobilized carbon filter media is greater than an equivalent amount of bulk PAC, further reducing overall process time and increasing product yield.
Pall Seitz AKS immobilized activated carbon filter media provides a streamlined process only requiring a single step. The feed stream is simply passed once through the filter at an appropriate flow rate to achieve the desired adsorption. This saves time, resources, and expense. It is nearly 100% free of carbon dust so operators and the workspace are much better protected. No additional mixing, filtration, or cleaning steps are needed.
Click Here To Download:Brochure: Stax™ Disposable Depth Filter Systems
Article: Evaluation And Implementation Of A Single-Stage Multimedia Harvest Depth Filter For A Large-Scale Antibody Process
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