Bosch Presents New Developments For The Pharmaceutical Industry

Modular machines for diverse requirements

• Filling and closing machine FXS Combi for nested syringes, vials and cartridges
• AIM 8 series: new generation of fully automated inspection machines
• New tablet press with even better accessibility

At Interpack 2014, Bosch Packaging Technology, a leading supplier of processing and packaging solutions, introduces numerousnew developments for the pharmaceutical industry. Thanks to their modular design, all machines can be flexibly adapted to current and future market requirements and integrated into line concepts. The exhibits include novelties for the processing, filling, packaging and inspection of liquid and solid dosage forms, as well as a comprehensive service portfolio.

Filling and closing machine for syringes, vials and cartridges
As a special Interpack highlight, Bosch presents the new FXS Combi, a filling and closing machine for pre sterilized nested syringes, vials and cartridges. The FXS Combi is the first machine of its kind with an integrated capping station. It can be flexibly integrated into existing line concepts, allowing for significant space savings. The FXS Combi is designed for low and medium output and can be combined with the proven bag and tub opening machines from Bosch. The presentation of an entire high-performance syringe line, consisting of the filling and closing machine FXS 5100 for pre-sterilized nested syringes, an ABO bag opener and an ATO tub opener, additionally underlines Bosch Packaging Technology’s competence in the processing of pre-filled syringes.

Sterilization tunnel HQL with reduced energy consumption
Bosch Packaging Technology has developed three new series for the sterilization and depyrogenation of pre cleaned containers. Thanks to its modular construction principle and its reduced energy consumption, the new HQL tunnels are especially efficient and can be customized to meet all requirements. The proven HQL series, which has been safely and reliably sterilizing and depyrogenizing pre-cleaned ampoules, vials, cartridges and syringes according to the laminar flow principle for over 30 years, forms the basis of this new development. The new HQL 6000 and 7000 series, as well as the HQL 8000 series presented at Interpack will be available in three standardized tunnel bandwidths of 600, 800 and 1 200 millimeters.

AIM 8 series: new fully automated inspection machines
The product group Bosch Inspection Technology, founded in the beginning of 2012 following the acquisition of Eisai Machinery, shows an overview of its product portfolio, ranging from manual to fully automated inspection machines for the detection of particles in pharmaceutical liquids and cosmetic container inspection. A special trade show highlight is the reveal of the AIM 8 series, the new generation of fully automated inspection machines from Bosch Inspection Technology. From its portfolio of manual inspection devices, Bosch further showcases the table top device MIH-LX as well as the camera-based ETAC Easy View, which are, amongst others, used for laboratory analysis. For the first time, Bosch presents an inspection system outside of Japan that examines tablets for defects such as coloration, breakage, foreign particles and other imperfections.

Tablet press with better accessibility
At Interpack, Bosch showcases a new tablet press which features particular easy handling. The low-maintenance tablet press is easy to access. A newly developed filling shoe, as well as fast product and format changeover enhance the machine’s output, making the tablet press especially suitable for customers with flexible requirements.

Solidlab 2 for up to eight processes on a small space
The laboratory device Solidlab 2 has been designed especially for research and development purposes and easy scale-up. The modular laboratory equipment can run up to eight processes on a small space: from mixing, drying, granulating and coating of small particles and pellets in the fluid bed module to tablet coating in the coater module. By utilizing a mutual air handling and control system, Solidlab 2 reduces costs, the amount of required floor space and operator training. In addition to the laboratorydevices, a Hüttlin granulation line with a HTG 300 high-shear mixer granulator and a HDGC 100 fluid bed system, as well as a XL Cota 150 tablet coater are on show.

Competence in capsule filling
At Interpack, Bosch demonstrates the flexible application of its capsule filling machines. The GKF 702 is suited for small and medium batches and all standard filling technologies, such as the dosator filling station from Bosch. The GKF Capsylon 3005, which is also displayed, focuses on a reliable output of up to 175 000 capsule per hour. It meets the demands of nutraceutical manufacturers for high efficiency, easy maintenance and operation.

Cartoning, serializing and aggregating for the highest safety
A further trade show novelty comes from secondary packaging. The new cartoning machine CUT 1405 offers higher flexibility, as well as newest servo and safety technology at reduced costs. The CUT 1405 can flexibly process different carton sizes to reliably and safely package a wide variety of packaging types such as bottles, vials, syringes, bags, sachets and sticks, as well as combination products. The CUT 1405 is equipped withquickly exchangeable carton sealing modules for tuck-in, glue and combined closures. Moreover, the intermittent horizontal cartoner is compatible with serialization and aggregation modules, which are also on show at Interpack.

New MRA assembly platform for disposable pens
From the machine portfolio for medical devices of its product brand Moeller & Devicon, Bosch introduces a new MRA rotary assembly machine platform. The platform was developed for the fully automatic assembly of 4-piece disposable pens at medium outputs of up to 70 pens per minute. Thanks to its open construction, the platform offers a good overview of all stations and processes, ensuring easy operation. The automatic transport and controls between the different stations reduce operator intervention and manual handling to a minimum. The platform can optionally be combined with down-stream labeling and packaging equipment.

Tailor-made service portfolio for improved equipment efficiency
At Interpack, Bosch also showcases its after-sales services portfolio. It focuses on solutions that improve packaging flexibility, machine efficiency and productivity. Machine upgrades and modernizations enable customers to flexibly adapt their existing equipment to new market requirements. During live presentations at the booth, the audience will be given an opportunity to take part in the “OEE Challenge” – a contest that tests participants’ speed, feeding accuracy and productivity on a completely overhauled horizontal wrapper. Customers can also find out how training sessions enhance efficient machinery handling. Moreover, Bosch demonstrates how tailor-made service packages support customers in achieving maximum output and minimum downtime, ultimately resulting in higher profitability of their Bosch packaging machines.

Bosch’s technologies are on display at Interpack 2014, Duesseldorf, Germany from May 8 to 14 in hall 6, booth A31 – C58.

About The Bosch Packaging Technology
Based in Waiblingen near Stuttgart, Germany, and employing 5,000 associates, the Bosch Packaging Technology division is one of the leading suppliers of process and packaging technology. At over 30 locations in more than 15 countries worldwide, a highly-qualified workforce develops and produces complete solutions for the pharmaceuticals, food, and confectionery industries. These solutions are complemented by a comprehensive after-sales service portfolio. A global service and sales network provides customers with local points of contact. For more information, visit www.boschpackaging.com.

About The Bosch Group
The Bosch Group is a leading global supplier of technology and services. According to preliminary figures, its roughly 281,000 associates generated sales of 46.4 billion euros in 2013 (Note: due to a change in the legal rules governing consolidation, the2013 figures can only be compared to a limited extent with the 2012 figures). Its operations are divided into four business sectors: Automotive Technology, Industrial Technology, Consumer Goods, and Energy and Building Technology. The Bosch Group comprises Robert Bosch GmbH and its more than 360 subsidiaries and regional companies in some 50 countries. If its sales and service partners are included, then Bosch is represented in roughly 150 countries. This worldwide development, manufacturing, and sales network is the foundation for further growth. In 2013, Bosch applied for some 5,000 patents worldwide. The Bosch Group’s products and services are designed to fascinate, and to improve the quality of life by providing solutions which are both innovative and beneficial. In this way, the company offers technology worldwide that is “Invented for life. For more information, visit www.bosch.com And www.bosch-press.com.