Newsletter | February 14, 2013

02.14.13 -- Dosing For Effect: Getting It Right The First Time

Pharmaceutical Online Newsletter
Departments:
Solid Dose
Logistics
Liquid Dose
Critical Environments
Packaging
Inspection
QA/QC
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Featured Focus: Liquid Dose
ARTICLE: Dosing For Effect: Getting It Right The First Time
By Robert McGregor, Brookfield Engineering Laboratories
Dosing is that critical step in producing a consumer product where manufacturing wants things to go as smoothly as possible. Two issues that affect acceptance are volume of material in the dose and proper proportions for constituent ingredients. This application note addresses the situation for both liquid and powder-based products.
CASE STUDY: Cost Savings Analysis Using Modular Skid Systems
PRODUCT: Liquid Prefiltration and Clarification
PRODUCT: Sartopore 2 XLG/XLI Sterilizing-Grade Filters
PRODUCT: Round Vibratory Screens
NEWS: The Medicines Company And Bristol-Myers Squibb Begin Global Alliance For Recothrom
» Packaging
DATASHEET: ATL Booklet Labels
By ATL (Ad Tape & Label)
SERVICE: Contract Packaging Facility
SERVICE: Contract Packaging Of Tablets And Capsules
» Solid Dose
ARTICLE: Key Elements For Success: Implementing PAT In An Oral Solid Dosage Plant
By Kjell Francois, Siemens AG
PAT (Process Analytical Technology) and QbD (Quality by Design) are the current buzzwords in the pharmaceutical industries, claiming to reduce waste, increase R&Q (reliability and quality) and production yields, and finally, to reduce costs. But introducing and implementing PAT, for instance, into an oral solid dose (OSD) plant, is a complex matter, and requires integration of different sources of data and different business layers. This article tries to give insight into this complexity, describing the different kinds of data, each with their specific properties.
DATASHEET: MECHATRON Midrange Vibratory Feeder
By Schenck AccuRate
PRODUCT: Mixer Loading Systems
PRODUCT: Capsule Filling
NEWS: Bayer Submits NDA For Hypertension Treatment
» Inspection
CASE STUDY: Avoid Product Recalls With Tablet Vision Inspection System
By Rusty Nelson, Daiichi Jitsugyo (America), Inc.
A pharmaceutical client was at risk of a product recall due to a capping problem with a new tablet formulation. Visual inspection at the packaging plant had identified that capped/laminated tablets had made it through to the packaging stage despite the tablets having met intermediate quality inspection.
CASE STUDY: Medical Device Package Inspection
DATASHEET: Inline Leak Testing Machine For Filled Bottles
By Bonfiglioli Engineering SPA
PRODUCT: Tablet Compression Accessories Catalog 4th Edition
PRODUCT: Tablet/Capsule Counting Inspection System: SureCount
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» QA/QC
ARTICLE: Removing Compliance Risk For Pharmaceutical Development And Manufacturing
By Mike Kuehne, ACSYS, Inc.
Organizations that consistently develop and launch new products efficiently, in an environment of increasing regulatory scrutiny successfully manage regulatory risk. Organizational regulatory risk management capabilities may become a competitive advantage for all development stages. This report will address the regulatory risk of pharmaceutical development and manufacturing through a review of regulatory trends during the period from Q1, 2011 through Q2, 2012.
WHITE PAPER: Measuring Viscosity Of Pastes
DATASHEET: Life Sciences Manufacturing: Overcome Key Business Challenges
By Kronos Inc.
BROCHURE: Outsourcing Cytotoxic Drug Development?
PRODUCT: Particle Segregation Testing Instrument
NEWS: Court Shuts Down U.S. Operations Of California Drug, Dietary Supplement Manufacturer
» Logistics
BROCHURE: Cargo Companion Brochure
» Critical Environments
CASE STUDY: Dust In Air Testing In A Downflow Booth
PRODUCT: Portable Cleanrooms
PRODUCT: Pharmaceutical Cleanrooms: Barrier Walls And Panels
PRODUCT: Laboratory CO2 Incubator
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