Drastically Reduced Isolator Decontamination Cycles

With the use of catalytic aeration, M + P is able to reduce the duration of the aeration phase in isolators by about 50 %. The aeration phase is the most time consuming cycle during H₂O₂ decontamination. Decontamination with VHP (Vaporous Hydrogen Peroxide) regularly takes place prior to production. Existing M + P isolators can also benefit from this development with a simple upgrade. A patent has been applied for.

Isolators are considered to be the safest method for guaranteeing a sterile filling environment in pharmaceutical production. In isolators, a vaporizer combined with a distribution system takes over the automated decontamination. M + P long ago decided on a system with distribution nozzles for dispersion of the H₂O₂. This decision also proves to be a decisive advantage for the newly developed catalytic aeration. Other isolator manufacturers use fans to distribute H₂O₂ in the process area (filling and capping). When recirculation fans are used, however, catalytic aeration cannot be performed without simultaneously negating the decontamination cycle.