By Trisha Gladd, Editor, Pharmaceutical Online and Bioresearch Online
We live in a fast-paced world driven by technology and competition, but in order to really stay ahead we have to be able to slow down and think. We have to allow our minds the time to create good ideas. So, how do we do this?
By Robert McGregor, Global Marketing and High End Product Manager, Brookfield Engineering Laboratories, Inc.
How do you bring consistency to QC testing? Pharmaceutical products that meet manufacturability criteria and provide high-level consumer satisfaction undergo a battery of tests before being distributed to the consumer. Using affordable instrumentation to perform QC tests, which certify that tablets, capsules, elixirs, ointments, etc. have the right physical properties, is essential for today's successful business.
By Fred Monsuur and Julia Poncher, W. R. Grace & Co
An excipient's role has traditionally been viewed as merely a filler or binder contributing to the stability of the end product. The full value that a formulation can bring to a final dosage form — or the real importance of ensuring an excipient's quality and performance — are often underestimated, overlooked, misunderstood, or disregarded. In reality, the functionality of the excipient can help determine whether or not a drug succeeds or fails.
By Marc Klingler, Segment Manager Hygienic Processing, Bürkert Fluid Control Systems
Thanks to high functionality within minimal space, multiport valves ensure compact processes, facilitate excellent cleaning, and increase process reliability, thereby contributing to improved product yield.
By Chuck Reed, B.Sc/MS Director, Weiler Engineering, Inc.
Blow/Fill/Seal (BFS) product usage has been widely established in the ophthalmic and respiratory therapy markets for some time, and lately, BFS technology has been gaining increasing worldwide acceptance in the parenteral drug marketplace, replacing traditional glass vial processing in a growing number of applications.
By Malcolm McLaughlin, Alconox, Inc.
The benefits of employing aqueous cleaning in pharmaceutical manufacturing are numerous. Virtually any pharmaceutical manufacturing equipment, from tablet press to a stainless steel mixing tank, can achieve its defined critically clean criteria using aqueous cleaning. Typically, aqueous cleaners are formulated to ensure maximal cleaning performance by using key ingredients such as surface active agents (surfactants), which are excellent wetting agents that allow the cleaning solution to penetrate into crevices while getting under soils to allow for removal. Often, very dilute solutions of aqueous cleaner effectively removes even worst-case substances off a variety of hard surfaces such as stainless steel, glass, plastic, or porcelain.