Case Study

Improving Suspendibility Of A Water-Insoluble API For Oral Suspension

Source: Metrics Contract Services

By Jeff Williamson, Dr. Brad Gold, Allen Lawson, and Keith Moore

To improve the suspendibility of a water- insoluble active pharmaceutical ingredient (API) in a sorbitol- based reconstitutable powder for oral suspension formulation using two novel excipients Sentry™Polyox™WSR N80, NF (polyethylene oxide) and Avicel CL-611® NF (microcrystalline cellulose/carboxymethylcellulose sodium).