By Rob Wright
During the ill-fated 1970 Apollo 13 mission to the moon, it was astronaut Jack Swigert who alerted ground control that something had gone terribly wrong when he uttered the phrase, "Houston, we've had a problem here." Those same words seem very fitting to the current state of affairs regarding the skyrocketing costs of drug discovery. Recent estimates place the expense of successfully bringing just one drug to market at between $350 million and $1.2 billion. However, in the past decade, companies that brought 4 to 13 drugs to market have watched the price tag reach even more stratospheric heights — orbiting at $5 billion and more. "I think the pain point has reached a threshold that's no longer bearable," states Dalvir Gill, Ph.D., CEO of TransCelerate BioPharma.
By John Van Tol, Harro Höfliger Packaging Systems
When it comes to the topic of capsule filling, the first and most immediate issue to consider is the equipment used for this purpose. Obviously, selection of the most suitable encapsulator is an extremely important consideration. There are several questions you need to ask while working through the selection process.
By Malcolm McLaughlin, Alconox
A great deal is known about how pH affects aqueous critical cleaning. Typically, alkaline cleaners are used on oily residues, and acidic cleaners are used on inorganic residues.
By Tony Harrison, U.K. Subject Matter Expert to ISO Technical Committee 209 Working Group
The intensely manual practices of cleanroom classification and routine monitoring are time-consuming and prone to data errors. Particle counter performance and accuracy can vary widely, leading to inaccurate particle counting data.
By Dr. Frank Westad, Chief Scientific Officer, CAMO Software
Multivariate statistical process monitoring (MSPM) has been established as a valuable tool for ensuring reliable product quality in the process industry. However, many organizations today are still not fully utilizing its potential to make significant improvements in their production environment.
By James Drinkwater, Bioquell Inc.
There is a need to improve efficiency in the pharmaceutical industry to meet the new challenges of globalization, competitiveness, and the increasing diversity of products.
By Luke Savage, LEED Green Associate
There is an ever-increasing demand for laboratories to have a reduced impact on the environment, as well as a lower cost to operate. With this continuing push for reduced energy consumption in laboratories, lab planners, architects, engineers, and lab managers are leaving no stone unturned.