Preparing Wet Granulations In A Planetary Mixer

Planetary mixers are ideal for wet granulation processes. Advantages include "one-pot" processing, high uniformity and yield, predictable performance, and ease of cleaning.

Granulation requires the addition of binding fluid/adhesive to a blend of powders. The liquid is added at a pre-determined rate to the batch while it is being mixed. The resulting wet mass is dried and sometimes passed through a mill to produce granules of a chosen size. The product is tested to determine particle size and other physical attributes that indicate suitability for downstream processing, i.e. pressing the granules into tablets or filling them into capsules.