Audio interview with Ron Guido …
Radio hosts Todd and Todd interview Ron Guido, president of Lifecare Services, LLC, to help you understand the nature of counterfeiting in the pharmaceutical industry and how brand protection best practices can help you preserve the integrity of your product throughout the supply chain, or in Ron's words, "A very complex supply network."
By Bob Applequist, Product Manager, Labconco Corporation
Controlled atmosphere glove boxes are designed to contain an internal inert gas environment, purified to some level. How to achieve the gas purities requires understanding a few fundamental concerns related to the chemistry and physics of gases. Most often misunderstood, and/or overlooked, are the properties of gas permeation and equilibrium. Physics describes permeation as the movement or penetration of gas molecules through a solid substance. All solid materials (glass, plastics, and steel) are permeable to some degree. This includes the material used in constructing glove boxes.
By Dr. Laura Ciccolini, Biopharma Technology Limited
Partnering with a specialist CRO is an ideal way to quickly and cost-effectively manage development. Biopharmaceutical manufacturing is increasingly focused on productivity and efficiency. A changing economic climate, together with the patent cliff of many major products, has resulted in drastic changes in the business models of a whole industry. It's no longer simply the repetitive, simple tasks that are outsourced, but increasingly complex, specialized tasks, including research and development, when pursuing the identification of new chemical and biochemical entities.
By Kenneth Maltas, Vice President of Engineering; Auston Matta, Engineering Team Lead R&D; Kevin O'Donnell, Technical Director; D'Arcy Ryan, Director of Marketing, ThermoSafe, Sonoco Protective Solutions
Storing and shipping highly temperature-sensitive drug products requires sophisticated packaging to ensure that the product remains safe and viable — from the manufacturing plant to the end user.
By Lei Li, Eli Lilly and Company
Utilization of prefilled syringes as a preferred container closure system for biologics has been increasing. As a primary container closure system, prefilled syringes must provide an integral barrier that protects drug product stability and sterility throughout its entire shelf life. Drug manufacturers are required to check and demonstrate that the system is capable of maintaining its microbial barrier integrity.
By Dale Natoli, Natoli Engineering Company, Inc.
If your business is in the tablet compression industry, then you are most likely using tablet compression tooling of the standard "B" and/or "D" configuration, regardless of the country you are in. Tablet compression tooling is often referred to as tooling, or more commonly, punches and dies.
By Bob Applequist, Product Manager, Labconco Corp.
During the past two decades in the United States there has been an increased usage of gloveboxes for a growing number of applications. Scientists, engineers, manufacturers, and facility managers have started using new terms for these devices in an effort to better define and categorize specific glovebox applications. The terms isolator, isolator glovebox, glovebox isolator, and barrier isolator are now commonly used to describe a glovebox and its functions. Unfortunately, expedient terminology usually falls short of defining the operational requirements for any specific glovebox.