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Transdermal and Topical Drug Delivery Systems

Source: Interpharm Press, Inc.

Representing the best technologies from major multi-national corporations and innovative start-up companies
Representing the best technologies from major multi-national corporations and innovative start-up companies, this collaborative effort presents an outstanding summation of the theoretical and practical aspects of transdermal drug delivery systems (TDDS) implementation.

The goal of effective optimized dermal/transdermal drug delivery with minimized skin irritation and toxicity is a recurring theme of the book. The text discusses new topical and transdermal drugs in the R&D pipeline, currently marketed dermal and transdermal therapeutic systems, step-by-step guidance in the development of topical and transdermal drug delivery systems, methods for clinical assessment of topical and transdermal products, details of percutaneous permeation enhancers, innovation formulation approaches to target topical drug delivery, regulatory considerations for IND, ANDA, NDA, PLA filings or transdermal products with FDA.

Chapters include:
Transdermal and Topical Delivery Systems: An Overview and Future Trends; Transdermal and Dermal Therapeutic Systems: Current Status; The Prediction of Transdermal Permeation: Mathematical Models; Preformulation Aspects of Transdermal Drug Delivery Systems; Preclinical Assessment of Transdermal Drug Delivery Systems; Safety Assessment of Transdermal and Topical Dermatological Products; Clinical Assessment of Transdermal Drug Delivery Systems; Design, Development, Manufacturing, and Testing of Transdermal Drug Delivery Systems; Transdermal Delivery of Beta-Adrenergic Therapeutics; Skin Absorption Enhancement by Physical Means: Heat, Ultrasound, and Electricity; Chemical Means of Transdermal Drug Permeation Enhancement; Oxazolidinones: A New Class of Permeation Enhancers; Drug Delivery From Topical Formulations; Formulation of Topical Drug Delivery Systems; Topical Formulation Development of Leukotriene B4 Receptor Antagonists for Psoriasis; Recent Advances in Topical Drug Delivery Systems; Topical Protective and Cosmetic Products; Biopharmaceutical Considerations For Topical and Transdermal Drug Delivery Systems

Interpharm Press, Inc., 15 Inverness Way E., Englewood, CO 80112-5776. Tel: 303-662-9101; Fax: 303-754-3953.

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