By Trisha Gladd, Editor, Pharmaceutical Online and Bioresearch Online
When discussing the challenges of manufacturing flu vaccines, the conversation often shifts toward how manufacturers can meet the global demand each year. Currently, there are some very innovative technologies aimed at addressing the challenge of manufacturing a larger supply of flu vaccines in a shorter amount of time, such as Novartis’ use of cell culture and Medicago and Fraunhofer’s use of tobacco plants. However, being able to deliver enough of a vaccine is only half the battle.
By Chris Freeman and Dr. Claire Freeman, Brookfield Engineering Laboratories, Inc.
Packaging is an emerging science that has become a great contributor to the success of the pharmaceutical industry. It has become the core sector for marketing and the means by which manufacturers can differentiate their products from those of their competitors.
By Dr. Egon Huefner, Bürkert Fluid Control Systems
When tablets are packaged in blisters, the plastic film must be the right temperature at the right moment: which is no easy task at an output of up to 1,300 blisters per minute. A customer-specific combination for proportional valve, temperature sensor, and controller master is using the regulation of cooling water flow. If needed, machine developers can implement 13 parallel-working temperature control circuits.
By Brian Haney, Ph.D., Director of Manufacturing, AMRI
Over the past few years a steady stream of contract manufacturing organizations (CMO) have added high-potency active pharmaceutical ingredient (HPAPI) production capacity. The expansions give biopharma executives charged with selecting HPAPI production partners an unprecedented number of options, but all this choice creates a problem.
By Brian McMillan, M.S.Pharm., VP Product Development
The tablet technology that brought Aspirin, Lipitor, and innumerable other drugs to billions of patients is evolving into multilayer and combination products.
By Dan Catizone, QuickSTAT
Much has been written about cold chain logistics, however, successful and efficient planning still presents many challenges. One of them is choosing an appropriate packaging system. (You can learn more about overcoming cold chain logistics challenges in our white paper, "Best Practices in Cold Chain Logistics Planning.")