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Article: The Use Of Syringe Filters For Analytical Sample Preparation
By LARRY SCHEER
Filtration is increasingly used as a protective measure in analytical sample preparation. As a result, there are more filter options to choose from than ever before, and each has its own performance properties. Because filter performance depends largely on application-specific conditions, understanding the differences between products can help avoid unexpected failures and costly system downtime.
Fortunately, industry studies have produced analytical guidelines for the comparative process, selection, and use of syringe filters to extend high-performance liquid chromatography (HPLC) column life, minimize extractables, and reduce adsorption of active pharmaceutical ingredients (APIs).
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