Walker Barrier Systems is a leading supplier of containment and aseptic systems for the pharmaceutical, biotech and nuclear industries. Our product line includes pharmaceutical isolators for containment of potent compounds and aseptic processing applications; Extract Technology brand downflow booths for operator protection from breathable dusts; and a full range of Extract Technology brand pack-off systems to safely offload powder products into drums or IBCs. Restricted Access Barrier Systems (RABS) are also available, providing unidirectional airflow and limited operator access during the pharmaceutical manufacturing process. We will custom design equipment to best suit your process or integrated equipment needs.
Our Mobile Clean Room (MCR) provides fast, flexible clean room manufacturing space without the considerable time and costs associated with more traditional clean room options. The “MCR” can be designed with ISO 7 or ISO 8, BSL1 and BSL2+ environments for pharmaceutical and biotech applications, or ISO 5 and ISO 6 environments for semiconductor applications. The MCR is delivered fully assembled to your facility ready to use. Extended-width units are available to increase manufacturing space.
Walker Barrier Systems
618 State Street
New Lisbon, WI 53950
Contact: Gary Partington
Hydrogen Peroxide (H2O2) decontamination is the most widely used and accepted form of decontamination in isolators.
These days several Pharmaceutical companies are moving to single use, flexible film isolators for containment of potent compounds during Pharmaceutical processing. Flexible film isolators have also been used for aseptic processes, like sterility testing.
Isolators have been around the Pharmaceutical Industry since the early 1980s and in the Nuclear Industry (glovebox technology) since the 1950s. The intent of isolators is to create an airtight barrier or enclosure around a piece of equipment or process which provides absolute separation between the operator and product. By Gary Partington
Walker Barrier Systems was tasked with providing a system to contain potent and toxic active pharmaceutical compounds to 0.5μg/m³ exposure level (TWA over operation duration), for an existing Lab space. The unit was designed for product filtration, drying in vacuum heat oven, hand sieving and discharging and final dispensing for further processing, using a Hicoflex system, for an existing Laboratory. By Gary Partington
While price is certainly an important reason for buying any piece of capital equipment, it is not always the top reason. There are important considerations to examine when selecting an isolator supplier to be certain that you are getting what you are paying for, before the purchase order is written. By Gary Partington
The Mobile Clean Room (MCR) is a self-contained manufacturing space fully constructed in our facility. It is shipped to customer facility on a double drop flatbed trailer in one piece and ready to hook up and use upon moving into place.
If you are considering purchasing one, here are five questions to answer that will help you prepare before contacting or working with a containment system vendor.
As isolators become more customized to meet the requirements of specific Pharmaceutical processes, the controls systems have been challenged to provide more safety and flexibility. By Walker Barrier Systems
Walker Barrier Systems was tasked with providing two downflow booths, each with integrated tray dryer (client provision) mounted in the side wall. The booth was to be used for filling trays with wet cake, as well as the dispensing of dried product from the trays into drums using a custom designed “tray dispensing hopper”.
The Walker Barrier Systems Six Glove Sterility Testing Isolator is designed to allow operators to perform sterility testing in an aseptic environment providing assurance of material integrity. By Walker Barrier Systems
This document provides an overview on how to properly validate sterility test isolator systems and then, via a case study, describes a strategy for streamlining the validation process when equivalent isolators and/or generators are installed in a sterility test suite. By James R. Rickloff, Partner/Scientific Director Advanced Barrier Concepts, Inc.