Containment & Isolation Feature Articles
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Reducing Bioburden Risks In Aseptic Manufacturing
8/11/2017
Manufacturers can benefit from this alternative transfer technology that has now been adapted to solve issues in aseptic handling.
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How To Prepare For Chamber Mapping In Life Sciences — 8 Critical Steps
7/17/2017
A failed chamber mapping study can lead to unnecessary costs in valuable biopharmaceutical production time or regulatory and product quality issues.
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Aseptic Production Automation To Reduce Risk And Cost
10/21/2015
This article discusses how to apply current isolation technologies with robotic systems to reduce the risk of microbial contamination in aseptic processes caused by human intervention.
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Increase In HPAPI Manufacturing Highlights Need For Containment And Isolation Systems
7/21/2015
An estimated 25 percent of globally manufactured drugs contain highly potent active pharmaceutical ingredients (HPAPIs). HPAPI drugs, which include small-molecule and biologic compounds as well as antibodydrug conjugates (ADCs), are often used in the treatment of cancer. The fastest growing segment of the HPAPI market are ADCs, a new class of therapeutic agents that deliver cytotoxic drugs selectively to antigen-expressing tumor cells. Non-oncology HPAPI compounds include hormones, narcotics, and retinoids.
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FAQ's: Regulated Films For Containment Solutions
9/11/2014
At ILC Dover, we are always "creating what’s next" by listening carefully to our customers. In response to customer input and emerging regulations, we've developed a robust new film to support our DoverPac® Containment Solutions line. This revolutionary product, ArmorFlex® 110, delivers permanent static dissipative properties while meeting FDA and 2002/72/EC requirements for food contact.
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A Novel Design To Contained Transfer Of Drummed Materials Using A Disposable Manufacturing Approach
4/20/2007
The Drum Transfer System (DTS) described in this article has been validated in a variety of processes requiring the contained transfer of drummed materials in pharmaceutical applications. Processing operations described here include milling, subdividing, charging, and repackaging. Submitted by ILC Dover
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The Answer To Final Pack Off Containment
2/27/2007
The DoverPac® continuous liner system provides the advantage of replacing packs without breaking containment, unlike using inflatable heads or having operators shuffle tube stock.
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Flexible Containment Solutions Guide: Mill Containment System - Jet Mills
The process for this application consists of the controlled feeding of a mill through a feeder. The powder is introduced into the feeder using a drum transfer system.
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Key Considerations When Purchasing Your Biological Safety Cabinet
The purchase of a biological safety cabinet should be made with much consideration. These cabinets serve as the Primary Engineering Control as the first line of defense in providing personnel, environmental and/or product protection against biohazards and potentially harmful agents in a range of laboratory, research, clinical and industrial settings.
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Sterile Drug Manufacturing Techniques: Key Benefits To Know
Although pharma manufacturers take stringent steps to ensure their production systems are as safe as possible, a fully gowned operator can still create as many 150,000 particles per minute.