Tablet Production Featured Articles

1. Solving Segregation Effects In Solid-Dosage Form Operations 4/17/2018

   Understanding segregation and how it is related to drug development cost is at the heart of solving this issue and is the topic of this article.

2. Early Detection Of Powder Flowability Challenges In Formulation Development Of Solid Dosage Forms 4/17/2018

   Understanding the impact of powder behavior during pre-formulation will ensure clinically effective products and provide critical process knowledge to design an efficient and reproducible manufacturing procedure.

3. How To Increase Regulatory Flexibility And Tablet Production Efficiency 8/5/2015

   The goal of every pharmaceutical developer is to create quality products that generate consumer satisfaction, require low cost, and have low risk.

4. The Key To Continuous Manufacturing 9/3/2013

   Ivo Backx points out that integration of all process automation architectures is essential if continuous manufacturing is to be rolled out successfully.

5. Accurate Bulk Density Measurement Maximizes Solid Dose Production 12/19/2012

   The most popular dosage form in the pharmaceutical industry is the compressed tablet. Fully two-thirds of all prescriptions are dispensed in a solid dosage form and half of these are compressed tablets. While it looks simple in its white or colored form, the compressed tablet is a complex mix of the active drug and a host of excipients.

6. Guest Column: Powder Characterization Techniques For Tableting Applications 6/25/2010
   Simple to administer, tablets are a feature of every day life. Tablet production has a history dating back more than a century, but retains its ability to frustrate. The drive towards faster production speeds, increasingly potent actives and the adoption of complex tablet structures present modern day tablet manufacturers with significant challenges. Understanding how to manipulate the properties of the blend towards better processing performance and high quality of final product is essential. By Tim Freeman, Freeman Technology
7. Tutorial: New Technologies Protect Pharmaceuticals Against Counterfeiting 4/6/2010
   Anticounterfeiting and traceability are different problems requiring different solutions. On the one hand, traceability requires standardization and interoperability among the various manufacturers and the intervening third parties within the supply chain up to the dispensing point. By Roland Meylan, AlpVision
8. Article: Better Wet Granulation: Development, Scale-Up And Manufacture 8/7/2009
   Wet granulation is a common unit operation in the pharmaceutical industry yet accurate endpoint detection remains a challenge. Here we examine the contribution that dynamic powder rheometry can make, highlighting its ability to detect the transition from wet mass to granulate with the required sensitivity. Quantification of this transition point, with a measure that is independent of process scale, accelerates development and scale-up and improves manufacture. By Tim Freeman, Freeman Technology
9. Tim Freeman Series On Powder Characterization For Pharmaceutical Operations 8/5/2009
   ‘Powder characterization for pharmaceutical operations’ is a series of six guest editorials contributed by Tim Freeman, Director of Operations at Freeman Technology, specialists in the measurement and understanding of powder behaviour.
10. Quadro Vac® Dust-Free Milling System 6/15/2006
    Quadro Engineering recently supplied a Quadro® Comil® and Quadro Vac® to the research laboratories of a large multi-national pharmaceutical manufacturer for use in tablet production