Tablet Production White Papers & Case Studies

1. Intro To USP <1062> - What It Is And Why You Should Use It 7/20/2023

   Knowing how to use USP <1062> helps manufacturers manage the wide variety of factors that can exacerbate production costs, or result in no product at all.

2. Helium Leak Detection Vs. Dye Leak Testing 11/22/2022

   A global pharmaceutical entity was experiencing early package failures from stability studies for a new drug product. Learn about the solution and the results obtained from this case.

3. Precision Powder-In-Capsule Micro-Dosing Accelerates Drug Development 6/1/2022

   Precision powder microdosing makes it possible to quickly get formulations to the clinic, saving time, money, and use of limited APIs.

4. Tablet Presses For Production Of Challenging Natural Medicines 3/7/2022

   A complex tablet press capable of delivering maximum performance but also suitable for free-flowing and sticky powders was the solution for this natural medicine manufacturer.

5. Hot Melt Extrusion: Improving Solubility Of Poorly Soluble Compounds 11/30/2021

   As you create your hot-melt extrusion (HME) strategy to manufacture amorphous solid dispersions (ASDs), there are several considerations to ensure your plan is flexible, robust, and comprehensive.

6. Determination Of Moisture Permeation During Product Shelf Life 12/27/2018

   How non-destructive headspace analysis information can be critical for QC groups performing stability studies, or for packaging development groups responsible for choosing the optimal packaging.

7. Lyo Chamber Moisture Mapping 12/27/2018

   Rapid non-destructive headspace moisture analysis from LIGHTHOUSE enables fast moisture determination of statistical numbers of lyo samples.

8. Root Cause Investigation Into A Possible Container Closure Integrity Failure 12/27/2018

   In cases where oxidation of the formulation causes discoloration and eventual degradation of the product, non-destructive headspace analysis tests can give deep insight into the root cause. Since the samples are not destroyed by the headspace analysis, further testing can be done to accurately correlate headspace conditions with other product characteristics.

9. Redefining Fast Melt For Pharma With 3D Printing 7/31/2018

   Adults and children alike often struggle with compliance and acceptance of medication regimens due to the sizes and shape of prescribed tablets. One pharmaceutical manufacturer sought to create a convenient, easy-to-swallow dosage form by taking an alternative approach: three-dimensional printing (3DP). This white paper outlines their approach to creating an FDA validated manufacturing process for rapidly disintegrating dosage forms.

10. 5 Steps To Increase Energy-Efficient Mixing 3/1/2018

    Mixer testing simulation trials are necessary to confirm the suitability of a specific mixing strategy. Explore five ways to increase energy efficiency in new and existing mixing processes.