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•Brochure: Tablet Coating in the Novel SUPERCELL™ Coater

Revolutionary tablet coater that accurately deposits controlled amounts of coating materials on tablets. Even if they are extremely hygroscopic or friable.

Tablet coating technology in the pharmaceutical industry has remained fundamentally unchanged for the past 50 years. Until now. Inconsistent and imperfect, this "standard" practice of tablet coating often delivers a non-homogenous product. Because the tablets are loaded in large rotating pans and vented for hot air drying, tablet edges can get grounded off, intagliations can get filled in by coating material, and edges and corners may not be coated with the same thickness as the tablet faces. The inaccuracy of deposition of coating material limits the use of modified release coatings. In a laboratory setting, it is necessary to coat several kilograms of tablets at one time, making Research & Development of a tablet dosage form costly and difficult.

Tablet Coating in the Novel Supercell™ Coater: Evaluation of Color Uniformity. A summary of the poster presented at the November 2004 AAPS Poster Session in Baltimore, Maryland. Supercell™ Coating Technology (SCT) was developed with the ability to uniformly and rapidly coat small batches of objects having a major diameter between 3 to 35 mm with a high degree of accuracy. The SCT coating apparatus is described in US patent 6,209,479 and EP patent EP 1,140,366 and eqv. [1-2]. The coater consists of a conical processing chamber that sits on top of a gas distribution plate (roto-nozzle). The roto-nozzle contains gas jets designed to accelerate the objects for coating, e.g. tablets, through the coating zone in a ballistic flight path. The gas jets impart momentum to the tablets such that they are rotating as they pass through the coating zone. Coating material is atomized by means of a specially designed low-momentum two-fluid spray nozzle located below the gas distribution plate. Normally, the momentum from a two-fluid nozzle can accelerate objects such as tablets fast enough that they are easily damaged when they strike a surface or fall. In SCT, the atomizing gas is mixed with low-pressure drying gas in order to dissipate the momentum generated in the atomizing process. Tablets are coated co-currently with the drying gas. At the end of the coating process, the tablets are pneumatically conveyed out of the processing chamber.

Downloads:
•Brochure: Tablet Coating in the Novel SUPERCELL™ Coater

GEA Process Engineering Inc. • 9165 Rumsey Road • Columbia, MD 21045
Tel. 410-997-8700 • E-mail: info@niroinc.com • Website: www.niroinc.com