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FEATURED ARTICLES

  • Outsourcing Solid Dose Manufacturing Trends In 2014
    Outsourcing Solid Dose Manufacturing Trends In 2014

    In 2014, the contract manufacturing market for solid dosage forms is anticipated to be $19.6B, representing 58% of the total CMO market value of $33.7B. While the market value percentage for solid dose has been drifting downward — likely related to the shift towards biologics, which are more expensive to develop and manufacture — the propensity to outsource oral solid dosage forms continues to grow modestly.

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WHITE PAPERS & CASE STUDIES

  • Fluid Bed System Triples Batch Sizes for Laboratorios Normon while Reducing Costs
    Fluid Bed System Triples Batch Sizes for Laboratorios Normon while Reducing Costs

    With the aim of reducing costs, Normon planned to significantly increase its batch sizes for certain products. The manufacturer needed to pay close attention to the high quality and safety standards and economic aspects, as well as flexible production sizes and times.

  • Efficiencies In Powder Dispersion For Manufacturers
    Efficiencies In Powder Dispersion For Manufacturers

    This white paper explores five tips for dispersing powders into liquid more efficiently.

  • Medication Errors -- A Threat To Patient Safety: Mitigating Errors With Tablet Appearance
    Medication Errors -- A Threat To Patient Safety: Mitigating Errors With Tablet Appearance

    Medical prescription drug errors by doctors, pharmacists and patients account for 1.5 million incidences of sickness, injuries or deaths in the U.S. each year. By Jay Anbil and Steve Yoder 

  • Film Coating For Pediatric Oral Solid Dosage Forms
    Film Coating For Pediatric Oral Solid Dosage Forms

    From a recent survey conducted within the pharmaceutical industry, by Colorcon, it was confirmed that oral solid dosage forms are a preferred choice for formulation of pediatric medicines.

  • Accelerating Lipid-Based Drug Formulation Through Application Of An Expert System
    Accelerating Lipid-Based Drug Formulation Through Application Of An Expert System

    Formulation scientists have become pivotal to pharmaceutical development, in that they are often faced with the daunting challenge of not only identifying the most suitable drug delivery platform among a myriad of options, but also developing and validating robust systems that address the challenges posed by increasingly complex drug candidates, in ever shortening time frames. By Eduardo Jule, Ph.D., Senior Manager, Formulation and Pharmaceutical Development

  • When Capsules Fall Apart, Who Is To Blame?
    When Capsules Fall Apart, Who Is To Blame?

    Capsule integrity is a given for established manufacturers with impeccable reputations.  Consumers, however, know from experience that not all capsules are made equal.  Some can be difficult to extract from the blister pack.  Others may have gel caps with cracks or, even worse, ruptures that allow the ingredients to spill out.  Is this a manufacturing problem?  Or has R&D neglected to implement a fool proof test methodology for evaluating capsule stability?  Compression and tension testing offer a technical approach with quantifiable results that can be used to assess capsule performance.

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PRODUCTS & SERVICES

Pharma Tablet Deduster With Wash-In Place: KD70 WIP Series

Pharma Tablet Deduster With Wash-In Place: KD70 WIP Series

The knowledge and experience gained over the years allowed development of another in a long line of Krämer irsts, the WIP deduster in 2000. Due to the pioneering innovation and constantly striving to improve and meet our customer’s requirements has led to the new generation KD70 WIP dedusters which sets another standard in high containment in the production of highly active and potent products.

Tablet Deduster For Large Scale Manufacturing: KD7030

Tablet Deduster For Large Scale Manufacturing: KD7030

High performance tablet deduster for largest dedusting capacities equipped with latest technology. Tablets are dedusted and conveyed with our unique acceleration control and helix in the most sensitive way.

Pharmaceutical Tablet Deduster: E80-N

Pharmaceutical Tablet Deduster: E80-N

Ideal for production of middle-sized charges and research applications.

Pharmaceutical Wet Granulation System: GranuLean

Pharmaceutical Wet Granulation System: GranuLean

The GranuLean wet granulation unit from Bosch combines a pharmaceutical high-shear mixer, a wet mill, and a fluid bed dryer into a compact and easily integrated granulation suite. Our patented Gentlewing pharmaceutical mixing technology in the high-shear mixer starts the process with uniform and rapid mixing and granulating of your product. The product is then metered from the high-shear mixer into the integrated wet mill for particle sizing. The wet product then gets automatically transferred into the fluid bed for the drying step. After drying, the product is discharged via a dry mill. As an alternative, the fluid bed can be used to granulate your product utilizing top spray or tangential spray technology. The produced granules are then ready for tabletting, encapsulation, or other solid dosage forms such as stick packs for pharmaceutical manufacturing.

Used Capsugel Capsule Filling Equipment

Used Capsugel Capsule Filling Equipment

One (1) used Glatt Fluid bed dryer, model GPCG2, stainless steel construction, 12 liter and 3 liter spray granulation bowls, 6.5 bar internal shock rating, intengrally mounted control panel, serial# 9080, built 2006.

Used GPCG2 Glatt Fluid Bed Dryer

Used GPCG2 Glatt Fluid Bed Dryer

One (1) used Glatt Fluid bed dryer, model GPCG2, stainless steel construction, 12 liter and 3 liter spray granulation bowls, 6.5 bar internal shock rating, intengrally mounted control panel, serial# 9080, built 2006.

Pharma Metal Detector For Tablets And Capsules

Pharma Metal Detector For Tablets And Capsules

Natoli Engineering Company is excited to announce the addition of two new metal detector models to its Tablet Compression Accessories Catalog. The CEIA Ultra High and High Sensitivity metal detectors ensure safe, high-quality tablets. They feature high sensitivity towards contaminating metals, whether ferrous, nonferrous or stainless steel, even when present in tiny quantities. Natoli has tested and approved these machines for our customers’ use and we are proud to offer an introductory special. Contact your local Natoli representative for more information.

Used Pharma Drum Lift and Dumper

Used Pharma Drum Lift and Dumper

One (1) used Drum lifter/dumper, for 24" drum, hydraulically operated, 3/4 hp pump.

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