Comparative Evaluation Of Automated Flash Chromatography And Preparative HPLC For Bench-Scale Purification Of A Broad Range Of Sample Types
The goal of a purification chemist is to deliver suitable quantities of high purity compounds in the shortest possible time. Two of the most popular purification techniques are Automated Flash Column Chromatography (AFCC) and Preparative HPLC. Traditionally, AFCC is characterized by the ability to load large amounts of material and has short purification times, while Prep HPLC is valued for high resolution separations resulting in very pure products. As a result, AFCC is often used as a preliminary technique whereby the crude sample is pre-purified before final high resolution purification using Prep HPLC. By Bopanna N.K., Chitra Sundararajan, and Mark Jacyno
WHITE PAPERS & CASE STUDIES
The Importance Of Steel Quality In Tablet Compression Tooling
Steel quality is the summation of how well a steel meets its specified chemistry, the cleanliness of the steel or degree to which it is free of impurities or inclusion, homogeneity of the microstructure, grain/carbide size and in some instances if it meets the mechanical requirements for that particular steel.
Fluid Bed System Triples Batch Sizes for Laboratorios Normon while Reducing Costs
With the aim of reducing costs, Normon planned to significantly increase its batch sizes for certain products. The manufacturer needed to pay close attention to the high quality and safety standards and economic aspects, as well as flexible production sizes and times.
Efficiencies In Powder Dispersion For Manufacturers
This white paper explores five tips for dispersing powders into liquid more efficiently.
Medication Errors -- A Threat To Patient Safety: Mitigating Errors With Tablet Appearance
Medical prescription drug errors by doctors, pharmacists and patients account for 1.5 million incidences of sickness, injuries or deaths in the U.S. each year. By Jay Anbil and Steve Yoder
Film Coating For Pediatric Oral Solid Dosage Forms
From a recent survey conducted within the pharmaceutical industry, by Colorcon, it was confirmed that oral solid dosage forms are a preferred choice for formulation of pediatric medicines.
Accelerating Lipid-Based Drug Formulation Through Application Of An Expert System
Formulation scientists have become pivotal to pharmaceutical development, in that they are often faced with the daunting challenge of not only identifying the most suitable drug delivery platform among a myriad of options, but also developing and validating robust systems that address the challenges posed by increasingly complex drug candidates, in ever shortening time frames. By Eduardo Jule, Ph.D., Senior Manager, Formulation and Pharmaceutical Development