INSIGHTS ON SOLID DOSE MANUFACTURING
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Navigating OSD Formulation Development And Leveraging CDMO Partnership
Collaborating with an experienced CDMO can provide the expertise and facilities needed to navigate oral solid dose formulation complexities and ensure compliance with regulatory frameworks.
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The Critical Role Of Weight Uniformity In Tablet Manufacturing
For tablet manufacturers, tablet weight uniformity plays an essential role in ensuring pharmaceutical products deliver accurate amounts of key ingredients in a formulation.
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Liquids, Soft Foods As Vehicles For Enteric Coated Bead Drug Product
Take a deeper look at the challenges and solutions involved in creating a child-friendly medication delivery system, and learn about the importance of collaboration and meticulous scientific processes.
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The Future Of Oral Solid Dose Development And Innovation
Tom Sellig, CEO of Adare, discusses the ongoing relevance of small molecules, oral solid dose development, trends like GLP-1, and innovations like 3D printing in pharmaceuticals.
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Optimizing DPI Production: Filling Technologies For Precision And Performance4/16/2025
Developing effective dry powder inhalers requires expertise across multiple disciplines, from particle engineering and device technology to manufacturing science and regulatory knowledge.
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers10/7/2025
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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Overload Setting – Tricks And Techniques9/23/2024
Learn how a partner company that is committed to assisting manufacturers with calibration and optimal set-point establishment can serve as a valuable resource in achieving optimal tablet production.
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A Technology Driven CDMO & Trusted Manufacturing Partner7/18/2024
Whether it's through extended release formulations or titratable dosage forms, we are dedicated to addressing the specific needs of different patient populations, including pediatrics and geriatrics.
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Customized Release Through Dispersed Dosage Formats6/13/2024
Typically, dosage format is based on the target product profile: how the developer envisions the product best addressing a clinical indication by maintaining population-wide efficacy.
SOLID DOSE MANUFACTURING SOLUTIONS
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Natoli Engineering’s NP-P20A single-station hydraulic tablet press is a favorite for the production of injectable micropellets and for marginal formulations requiring deep-fill. The NP-P20A meets the FDA’s requirements for batch reporting and secure data management under CFR 21 Part 11 compliance.
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Used ACG-Pam Capsule Filler, Model AFT LAB.
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Used Key International single station bench top tablet press, model: SC-2. 1.5 ton compression pressure, approximately .5" max tablet diameter, .5625" max depth of fill, manual operation, serial# JI4786.
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Used 19 MM APV Baker Perkins twin screw co rotating extruder, model MP-19-TC, 19 mm diameter screws, 40:1 l/d, electrically heated, water cooled barrel, split barrel design, 2 kw dc motor, 500 rpm screw spped, with Ktron main feeder, (2) Brabender auxiliary feeders, (3) Zenith melt pumps, FTS chiller, external control panel, with associated screws, screw elements, control panel, 220 volt, CE rated, APV serial# NEF990028-701/1, Baker Perkins serial# TS99535, project# 99TS196, built 1999.
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Used GlobePharma MiniBlend twin shell blender, model MNB-1 with 2 quart, 1 quart, and 0.5 quart stainless steel shells, t V-Cones, .1 hp 110 volt motor, serial# 12098879.