INSIGHTS ON SOLID DOSE MANUFACTURING
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![Douglas CDMO_softgel 2-Resized]( "Softgel Formulation: Addressing Stability, Shelf-Life, And Bioavailability")
Softgel Formulation: Addressing Stability, Shelf-Life, And BioavailabilityA CDMO that has expertise and resources in softgel formulation can help companies address stability issues, improve drug bioavailability, or ensure compliance with regulations.
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![HPAPIS Production Where Micrograms Matters]( "HPAPIS Production: \"Where Micrograms Matters\"")
HPAPIS Production: "Where Micrograms Matters"In HPAPI manufacturing, micrograms make a difference. Risk‑based containment, smart facility design, and exposure limits safeguard people, product, and performance.
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![GettyImages-1214112149-lab-team-collaboration-research]( "Less Mess, Less Stress, Best Expressed: An Alternative To Spray Drying")
Less Mess, Less Stress, Best Expressed: An Alternative To Spray DryingAlthough well-established processes, spray drying and hot-melt extrusion can be outperformed in bioavailability, cost-savings, manufacturing speed, environmental impact, and more.
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![GettyImages-186750891-Isolator]( "The Crucial Role Of Cleaning In Effective VPHP Decontamination For Isolators")
The Crucial Role Of Cleaning In Effective VPHP Decontamination For IsolatorsEffective isolator cleaning is crucial for vapor phase hydrogen peroxide (VPHP) decontamination. Proper tools, techniques, and training ensure sterility, and regulatory compliance.
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Improving API Solubility Using Hot Melt Extrusion Formulation2/27/2025
Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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Functional Release Multiparticulates Slam7/17/2024
Review Adare Pharma Solutions’ innovative technologies and learn how these capabilities can improve patient outcomes and improve manufacturing efficiency.
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How To Address Your Solid Dosage Processing Needs10/27/2025
Unlock the keys to consistent solid dosage products. Learn to align unique product needs with optimal processing requirements and equipment strategies. Gain a roadmap for improved quality and reproducibility.
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The Future Of Sustainable Amorphous Dispersion Development4/15/2026
Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.
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Future Of Pharma Packaging: Trends, Tech, And Patient Solutions9/25/2025
Explore how traditional and innovative pharmaceutical packaging formats improve patient adherence, support emerging therapies, and shape the future of drug delivery and treatment outcomes.
SOLID DOSE MANUFACTURING SOLUTIONS
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![30 Liter Becomix Mixer Homogenizer]( "Used 30 Liter Becomix Pharmaceutical Mixer Homogenizer: Model RW30")
Used A Berents BECOMIX planetary mixer, model RW 30, stainless steel construction, 60 liter total capacity, 30 liter working capacity, chamber rated -1/2 bar(-14.5/29 psi) at 134 c internal, jacketed for 4 bar(58 psi) at 152 c, top mounted variable speed agitator with side wall scrappers, bottom mounted homogenzier, dome top with lift/lower mechanism, cone bottom, with on board controls and external control panel, 3/50/400 volt, Fabr# 011/1-586, built 1996.
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![19 mm Baker Perkins Twin Screw Extruder]( "Used 19 mm Baker Perkins Twin Screw Extruder")
Used 19 MM APV Baker Perkins twin screw co rotating extruder, model MP-19-TC, 19 mm diameter screws, 40:1 l/d, electrically heated, water cooled barrel, split barrel design, 2 kw dc motor, 500 rpm screw spped, with Ktron main feeder, (2) Brabender auxiliary feeders, (3) Zenith melt pumps, FTS chiller, external control panel, with associated screws, screw elements, control panel, 220 volt, CE rated, APV serial# NEF990028-701/1, Baker Perkins serial# TS99535, project# 99TS196, built 1999.
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![mdoel CF360EX]( "Used Vector Granulator: CF360E")
One (1) used Vectro granulator, mdoel CF360EX, stainless steel construction, 3-5 kg capacity, xp design with controls, 220 volt, serial# CF-110, new 1982.
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![Milling Isolators]( "Micronizing And Milling Isolators For Drug Manufacturing")
Over many years, Dec has acquired recognized expertise in designing and supplying an extensive range of isolators enclosing a mill or a MC DecJet® spiral jet mill for either individual or combined operation.
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![GettyImages-1311641109-capsule-tablet-pill-OSD-oral-solid]( "Oral Solid Dose Formulation And Lab Scale Capabilities")
Natoli Scientific is dedicated to developing high-quality affordable products for your market needs.
We provide a formulation design based on a strong scientific understanding and decoding interplay of materials and process parameters to ensure product integrity. We use traditional as well as principles of ‘Quality by Design (QbD)’ to develop robust lead prototype formulations. The early sound scientific investment in product development saves time and money during scale-up and commercial manufacturing.
