INSIGHTS ON SOLID DOSE MANUFACTURING

SOLID DOSE MANUFACTURING SOLUTIONS

  • Natoli’s line of efficient tablet presses combine remarkable tablet production, automation and dependability.

  • Natoli Scientific offers manufacturing services of oral solids at a pilot scale and drug products for clinical trials.

    We also offer full-scale commercial manufacturing service till you are ready with your own manufacturing facility to avoid delay in the commercial launch.

    Team Natoli understands the complexity of the tablet manufacturing process over more than half a century. We are ready to shoulder every step of the tablet manufacturing chain from blending to granulation, to milling, to compression, to coating. Our manufacturing capabilities are backed up by our expert scientific team, who are ready to offer guidance in product development, technical transfers, and scale-ups.

  • ROSS Dual Shaft Mixers are durable, versatile systems designed for precise processing of high-performance formulations across diverse rheologies, solids loading, temperatures, and pressures.

  • Dec offers filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.

  • Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.