INSIGHTS ON SOLID DOSE MANUFACTURING
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How To Handle Intrinsic Product Powder Particles
Powder filling creates intrinsic particles that interfere with continuous monitoring. Risk‑based strategies must separate product dust from true contamination to meet Annex 1 requirements.
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Isolators For Pharmacy Compounding – Time For Change?
Maintaining a contamination-free environment is crucial in drug compounding. Learn how isolator systems can improve safety, efficiency, and regulatory compliance.
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Exploring The Future Of Tablet Compression Across Emerging Industries
Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.
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Tablets And Capsules: Overcoming Similar Obstacles In Production
Explore how understanding specific USP chapters can address common tablet and capsule production challenges and ensure high-quality results in this essential pharmaceutical process.
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Taste-Masked Dosage Forms For Pediatric Oral Delivery: An Industrial Perspective7/18/2024
Leveraging strategies and technologies for pediatric patient compliance for taste masking and controlled release in pharmaceutical products, enables flexibility in dosage and format options.
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Zhunan Facility Site VR Tour12/23/2025
Bora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
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Patient Adherence With A Novel Dosage Form11/13/2025
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Minitablets: Enhancing Safety And Palatability For Pediatric Medicines1/15/2026
Leverage minitablet technology to create flexible, easy-to-swallow, and palatable pediatric formulations that improve adherence and meet evolving regulatory requirements.
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Advancements In Tablet Compression Tooling: What Manufacturers Need To Know10/30/2025
Discover how continuous manufacturing, AI-driven digital twins, and advanced tooling materials are transforming tablet compression to boost quality and cut operational costs in pharmaceutical production.
SOLID DOSE MANUFACTURING SOLUTIONS
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Dec provides unique solutions to charge process equipment such as reactors, mixing vessels or dryers in a fully safe manner eliminating the need to connect the isolator directly to the equipment to be charged or to install the isolator on an upper floor. A single isolator system can be used for multiple vessels charging.
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Used MG2 continuous motion capsule filler, model Planeta100, nominally rated up to 100,000 capsules/hour, currently set up for microdose capsules, multinet weight control unit less scale system, 460 volt, serial# 4697, built 2014.
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AST’s line of table-top machines, GENiSYS® Lab, are ideal systems for drug product development and cGMP production applications. Each system is designed to automate the critical aseptic operations for vial, syringe and cartridge processing to reduce contamination risk and product variability. These table-top systems are engineered to have complete compatibility with cleanroom environments, including Laminar Air Flow Hoods, Bio-Safety Cabinets and aseptic isolators.
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Natoli organization is a reputed leader with more than a half century experience in the tablet manufacturing technology.
We understand tablets better. We are here for serving your needs to overcome challenges associated with commercial manufacturing of solid dosage forms across the globe (North America, Europe, Asia).
Our Natoli scientific team uses holistic approach to understand and solve important tableting problems like capping, lamination, picking, and sticking. We integrate scientific information gathered at material, process, and instrument level to understanding and decode root causes of these common tableting issues.
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Natoli Engineering Company, Inc. provides high quality tablet compression tooling, presses, parts, accessories, and services to the nutritional/vitamin supplement industry. With more than 40 years of industry experience, we are uniquely qualified to meet your tableting needs.