INSIGHTS ON SOLID DOSE MANUFACTURING
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![Dalton photo 2]( "How To Handle Intrinsic Product Powder Particles")
How To Handle Intrinsic Product Powder ParticlesPowder filling creates intrinsic particles that interfere with continuous monitoring. Risk‑based strategies must separate product dust from true contamination to meet Annex 1 requirements.
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![Natoli - FastLok video]( "FastLok™ Die Table Surface Overview")
FastLok™ Die Table Surface OverviewLearn about a toolless, removable surface that allows for rapid, on-turret plate replacement in minutes, not weeks, significantly improving operational efficiency.
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![Aseptic Filling GettyImages-1087219366]( "A Brief History Of Aseptic Processing")
A Brief History Of Aseptic ProcessingFrom Bunsen burners to advanced isolators, aseptic processing has evolved significantly. Delve into the evolution of this crucial manufacturing method, from its early sterilization techniques to today's highly controlled and regulated environments.
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![Blister Solutions]( "Blister Solutions")
Blister SolutionsWith over 6,000 tooling parts and an in-house machining center to ensure precision, explore this versatile blister service that provides both Thermoformed and Cold-Formed solutions.
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6 Strategic Pillars For Selecting A Drug Packaging Partner4/14/2026
Early engagement with an expert packaging partner supports safe, cost-effective drug development and logistical success from precommercial stages through full market launch.
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Zhunan Facility Site VR Tour12/23/2025
Bora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery1/27/2025
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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Optimizing Tablets For Even Splitting: The Pressure Sensitive Bisect Design11/11/2024
The pressure-sensitive bisect design allows accurate tablet splitting by maximizing facet width, optimizing angles, and balancing radius values for durability and user-friendly administration.
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Predicting Drug-Loading Limits In Tablet Formulations7/15/2026
Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Sterile Mfg]( "Sterile Manufacturing Pharmaceutical Equipment And Technologies")
Recent years have shown steady growth in manufacturing sterile, high potent products in the pharmaceutical industry. Antibiotics for intravenous or intramuscular injection in powder form such as Ceftriaxone Sodium for example, need to be produced under sterile conditions.
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![Natoli AIM™ Data Acquisition & Analytical Software for the NP-RD10A Tablet Press]( "Natoli AIM™ Data Acquisition & Analytical Software for the NP-RD10A Tablet Press")
Natoli Engineering now offers AIM™ Data Acquisition & Analytical Software for the Natoli NP-RD10A research and development tablet press. The combination of AIM™ Software and this R&D tablet press enables the researcher to evaluate formulation properties and identify potential tableting issues—including capping, lamination, sticking/picking, and tablet robustness—during the tablet development process. Plus, the software can optimize tablet tensile strength and lubrication for successful large-scale manufacturing production.
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![GettyImages-1311641109-capsule-tablet-pill-OSD-oral-solid]( "Oral Solid Dose Formulation And Lab Scale Capabilities")
Natoli Scientific is dedicated to developing high-quality affordable products for your market needs.
We provide a formulation design based on a strong scientific understanding and decoding interplay of materials and process parameters to ensure product integrity. We use traditional as well as principles of ‘Quality by Design (QbD)’ to develop robust lead prototype formulations. The early sound scientific investment in product development saves time and money during scale-up and commercial manufacturing.
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![ConveyingOfGranules.jpg]( "Conveying Of Granules, Flakes And Large Sized Particles: Transbatch")
The patented Transbatch system relies on modern technology to safely convey and dose granules and other solids under critical installation conditions in terms of both transfer length and height.
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![Powder Rheology Feature]( "Powder Rheology Accessory")
The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling the characterization of behaviors during storage, dispensing, processing, and end-use.
