INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-1465073074 tablets, OSD, pills]( "Improving Stability Through Science-Led OSD Reformulation")
Improving Stability Through Science-Led OSD ReformulationA marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.
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![GettyImages-2176475661 tabet press, pharma manufacturing]( "Navigating High-Potency OSD Manufacturing")
Navigating High-Potency OSD ManufacturingLearn how containment strategy, process design, and early risk‑based decisions influence operator protection, compliance, and long‑term manufacturing success as potency levels continue to rise.
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![GettyImages-1465073074 tablets, OSD, pills]( "A Powerful Non-Destructive Tool For Tablet Characterization")
A Powerful Non-Destructive Tool For Tablet CharacterizationDiscover how X-ray micro-CT provides vital, non-destructive analysis of a tablet’s internal 3D physical structure. This structural insight is essential for troubleshooting defects and confirming performance.
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![GettyImages-1208573753-scientist-fizz-solubility-lab-glass]( "Improving API Solubility Using Hot Melt Extrusion Formulation")
Improving API Solubility Using Hot Melt Extrusion FormulationSolubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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How To Fast-Track Your Oral Solid Dose To Phase 12/17/2026
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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Patient Adherence With A Novel Dosage Form11/13/2025
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Delivering API-In-Capsule For Potent, Low-Flow Compounds9/9/2026
See how an automated capsule-filling approach addressed poor-flow APIs, improved operator safety, and supported fast scale-up for clinical supply needs.
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A Brief History Of Aseptic Processing3/27/2025
From Bunsen burners to advanced isolators, aseptic processing has evolved significantly. Delve into the evolution of this crucial manufacturing method, from its early sterilization techniques to today's highly controlled and regulated environments.
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Precision In Miniature: Optimizing Multiparticulate Formulations For Pediatric Oncology9/9/2026
When an oral liquid formulation of crizotinib failed pediatric trials due to intolerable taste and irritation, a multiparticulate approach offered a technically demanding but viable path forward.
SOLID DOSE MANUFACTURING SOLUTIONS
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Handling today’s higher-potency active pharmaceutical ingredients (HPAPIs) presents ever-increasing regulatory concerns — especially within manufacturing-area isolators and lab areas, and for flexible GMP chambers where airflow, temperature, humidity and pressure differentials exist from room to room.
The JetVent™ system’s precise fan speed delivers accurately controlled negative air pressure to ensure proper flow into flexible-wall isolators, while reducing the risk of worker exposure.
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![Pharmaceutical Glove Isolator Tester FZ-GTS 4.0]( "Pharmaceutical Glove Isolator Tester: FZ-GTS 4.0")
Maximize glove testing efficiency
Improve your glove testing with the FZ-GTS 4.0. This innovative system delivers unmatched flexibility to adapt to your testing needs, seamlessly integrating with existing workflows for increased efficiency.
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![cdmo-solid-dose-GettyImages-1432665138]( "Solid Form Screening")
Solid form screening optimizes drug properties by evaluating polymorphs, salts, and cocrystals to improve solubility, stability, and manufacturability using advanced analytics.
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![Dec Group Sterile Process small]( "Overcoming Aseptic Manufacturing Challenges To Prevent Contamination")
The pharmaceutical industry has steadily moved to increased production and handling of sterile highly potent active ingredients (HPAPIs). Dec’s containment technologies comply with pharmaceutical quality manufacturing standards and are available for aseptic operations.
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![API Mfg]( "API Manufacturing And Material Handling Equipment")
Active pharmaceutical ingredient (API) manufacturing requires powder handling in a GMP and contained manner. Similar to chemical manufacturing, operations like charging powders into a chemical reactor, emptying a centrifuge or charging and discharging a dryer are standard processes.
