INSIGHTS ON SOLID DOSE MANUFACTURING

SOLID DOSE MANUFACTURING SOLUTIONS

  • Solid form screening optimizes drug properties by evaluating polymorphs, salts, and cocrystals to improve solubility, stability, and manufacturability using advanced analytics.

  • Used Syntegon high speed capsule filler, model KKE 1700, speeds up to 103,200 capsules/hour, 758541, built 2022.

  • Used Freund-Vector TFC-220 Pilot Scale Roll Compactor/Granulator, stainless steel construction, 20g - 20kg/hour capacity, with 200mm diameter x 20mm roll face rolls, grooved rolls, product hopper with integrated tapers de-aeration screw, with bottom mill, operator HMI touch screen, 230 volt, serial# RC-330, built 2012.

  • Natoli organization is a reputed leader with more than a half century experience in the tablet manufacturing technology.

    We understand tablets better. We are here for serving your needs to overcome challenges associated with commercial manufacturing of solid dosage forms across the globe (North America, Europe, Asia).

    Our Natoli scientific team uses holistic approach to understand and solve important tableting problems like capping, lamination, picking, and sticking. We integrate scientific information gathered at material, process, and instrument level to understanding and decode root causes of these common tableting issues.

  • Used 60" O'Hara FastCoat coating pan, model FC400 (60xc5), stainless steel construction with 60" diameter perforated Pan, solvent rated design, O'Hara advanced controls with Allen Bradley Compact Logix PLC, PC and HMI units, O'Hara manifold with Schlick nozzle spray arm, built in Watson Marlow peristaltic pump with Micromotion mass flow and recirculation system, reverse pan unloading, outdoor rated air handling unit (AHU) with preheat steam coil, chilled water dehumidification unit, steam reheat with face/bypass temp control dampers, HEPA module, Camfil DCU with FIKE suppression and isolation system, bag in bag out with exhaust HEPF module, 480 volt, system serial# 4501, built 2020.