INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-2024513353 drug manufacturing]( "An Alternative Method Of Drug-Excipient Characterization")
An Alternative Method Of Drug-Excipient CharacterizationIsothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.
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![Bora Pharmaceuticals - Zhunan Facility Site VR Tour]( "Zhunan Facility Site VR Tour")
Zhunan Facility Site VR TourBora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
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![Natoli - EZ Level]( "Maximize Uptime And Yield With This Feeder Base Leveling System")
Maximize Uptime And Yield With This Feeder Base Leveling SystemLearn how a patented leveling system provides real-time, three-gauge feedback, ensuring precision, maximizing uptime, and protecting your critical production equipment.
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![Natoli - Fundamentals Of Power Blending Simulations]( "Fundamentals Of Power Blending Simulations")
Fundamentals Of Power Blending SimulationsPredicting blending quality doesn't have to be a guessing game. Learn how to leverage virtual prototypes to make informed decisions and minimize costly trial-and-error in tablet manufacturing.
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Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months2/26/2026
A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
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6 Strategic Pillars For Selecting A Drug Packaging Partner4/14/2026
Early engagement with an expert packaging partner supports safe, cost-effective drug development and logistical success from precommercial stages through full market launch.
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Improving API Solubility Using Hot Melt Extrusion Formulation2/27/2025
Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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Innovations, Solutions, And USP <1062> With Scale Up11/4/2025
Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
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Combining Patient Centricity And Commercial Viability In Pediatric Product Development8/15/2024
Medication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.
SOLID DOSE MANUFACTURING SOLUTIONS
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![R&D Pharmaceutical Tablet Press: NP-RD30]( "R&D Pharmaceutical Tablet Press: NP-RD30")
Natoli Engineering is quickly becoming the leader in R&D tablet presses with this next-generation rotary tablet press. Designed to help solve formulation and scale-up challenges, the NP-RD30 rotary R&D tablet press replicates the design and functionality of a production press. The turret velocity of the NP-RD30 can reach that of production presses, meaning dwell time can be more accurately established during research and development.
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![iStock-1191001266-tablet-pill]( "Oral Solid Dose Formulation Troubleshooting Support Services")
Natoli organization is a reputed leader with more than a half century experience in the tablet manufacturing technology.
We understand tablets better. We are here for serving your needs to overcome challenges associated with commercial manufacturing of solid dosage forms across the globe (North America, Europe, Asia).
Our Natoli scientific team uses holistic approach to understand and solve important tableting problems like capping, lamination, picking, and sticking. We integrate scientific information gathered at material, process, and instrument level to understanding and decode root causes of these common tableting issues.
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![AST innovation]( "A User-Friendly Solution For Fill-Finish Professionals")
When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
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![Used Bausch & Stroebel Powder Filling System SP-100]( "Used Bausch & Stroebel Powder Filling System: SP-100")
Bausch + Strobel SP-100 Powder filling Machine with control cabinet, stainless steel construction, with filler funnels and auger, serial# 51181, built 1998.
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![MG2 PLANETA 100 Continuous Motion Capsule Filling Machine]( "Used MG2 PLANETA 100 Continuous Motion Capsule Filling Machine")
Used MG2 PLANETA 100 continuous motion capsule filler, nominally rated up to 100,000 capsules/hour, with touch screen HMI, vacuum system, serial# 4661, built 2010.
