INSIGHTS ON SOLID DOSE MANUFACTURING
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Layer By Layer: 3D Screen Printing And The Future Of Drug Development
3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.
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Cytiva's Aseptic Filling Workcell User Group
Discover how global collaboration among aseptic filling experts is driving innovation and improving operations.
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Powder Rheology: Gateway For Tablet Sticking Insights
Powder rheology offers a scientific method to predict and mitigate tablet sticking issues, helping to ensure smoother pharmaceutical production cycles through early material and tooling selection.
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HPAPI Containment: A Full Lifecycle Safety Innovation
Containing highly potent APIs across a full operational lifecycle requires a structured approach that addresses hazard scoring, quality by design, performance testing, and safe enclosure disposal.
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Integration From Formulation Development To Manufacturing, Packaging2/27/2025
Adare Pharma Solutions' Pessano, Italy facility offers 220,000 sq. ft. of end-to-end services, including R&D, formulation development, clinical and commercial manufacturing, packaging, and advanced analytical capabilities.
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Benefits Of Isolator Technology In Fill-Finish12/10/2025
Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery1/27/2025
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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NanoImprove The Performance Of Your Formulations9/24/2024
Learn how Nanoforming can help improve the performance of your molecule by increasing drug loads, improving bioavailability, enhancing drug delivery profiles, and supporting product differentiation.
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How Solid-State Characterization Shapes Drug Development7/23/2026
Mark Benger, Site Director at Cambrex Edinburgh, on solid-state characterization as an insurance policy — front-loaded work that quietly determines whether a program survives the jump from kilos to tonnes.
SOLID DOSE MANUFACTURING SOLUTIONS
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Forming part of 3P innovation’s Discover Range, this early-stage development unit uses two sets of die punches to compress pellets and seal them within a blister strip. Used predominantly for dry powder inhalers (DPIs), the ultra-compact filler fits on your lab benchtop.
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ILC Dover is 100% focused on containing your process to get your product to market fast, safe, and pure. Our single-use containment solutions leverage our patented and industry-leading ArmorFlex® films to deliver extreme durability for a lower cost.
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Natoli Engineering Company, through its Carlisle Precision Encapsulation Parts subsidiary, manufactures premium change and spare parts for many brands of encapsulation machines.
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Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
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Antibody‑drug conjugate services support development from early clinical stages through commercial manufacturing with integrated analytics, containment expertise, and scalable conjugation capabilities.