INSIGHTS ON SOLID DOSE MANUFACTURING
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Ask Us Anything: Eric Fang On Lithiation Chemistry
Eric Fang, General Manager of Snapdragon Chemistry, on why lithiation chemistry resists batch scale-up — and how a decade spent understanding static mixing lets Snapdragon carry these reactions from milligrams to metric tons.
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Global Regulatory Harmonization: Comparisons In Aseptic Barrier Systems
Compare global aseptic standards from the FDA, EMA, PIC/S, and WHO. Gain insights into how advanced barrier systems harmonize international requirements to ensure sterile product integrity and safety.
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Maximum Protection With Superior Quality
See how this automated capsule filling technology integrates high-containment isolators and 100% inline checkweighing to ensure precise dosing, operator safety, and continuous quality control
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Advancements In Tablet Compression Tooling: What Manufacturers Need To Know
Discover how continuous manufacturing, AI-driven digital twins, and advanced tooling materials are transforming tablet compression to boost quality and cut operational costs in pharmaceutical production.
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How Dosage Form Decisions Shape Pediatric And Geriatric Drug Development8/27/2026
Developing pediatric and geriatric pharmaceuticals requires customized strategies beyond tablet crushing, balancing specific age-related palatability, packaging, real-world administration, and lifecycle management needs for optimal patient outcomes.
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Tablet Logo Legibility: A Critical Component Of Consumer Health9/16/2026
Optimizing tablet debossing geometry balances regulatory legibility standards with compression efficiency, preventing sticking, picking, and film coating defects.
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Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling7/15/2026
Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.
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6 Strategic Pillars For Selecting A Drug Packaging Partner4/14/2026
Early engagement with an expert packaging partner supports safe, cost-effective drug development and logistical success from precommercial stages through full market launch.
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Solubility Enhancement Via Amorphous Solid Dispersions2/27/2025
Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
SOLID DOSE MANUFACTURING SOLUTIONS
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Establish safe barrier protection in minutes with a portable benchtop isolator. Secure containment for hazardous materials or inert gas processing across flexible laboratory scales.
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Open RABS as a housing for aseptic processes, e.g., filling, loading, and unloading of freeze dryers. Product protection is achieved by a barrier (oRABS housing with gloves) between the operator and the product.
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Used Korsch XL 400 2-Layer rotary tablet press. 35 station with B turret, 29 station with D turret. Serial# K1500036, built 2001.
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Handling highly potent active pharmaceutical ingredients safely requires precise pressure control and automated breach response that many facilities struggle to maintain consistently.
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When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?