INSIGHTS ON SOLID DOSE MANUFACTURING
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![Innovations, Solutions, And USP <1062> With Scale Up]( "Innovations, Solutions, And USP <1062> With Scale Up")
Innovations, Solutions, And USP <1062> With Scale UpOptimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
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![Natoli - EZ Level]( "Maximize Uptime And Yield With This Feeder Base Leveling System")
Maximize Uptime And Yield With This Feeder Base Leveling SystemLearn how a patented leveling system provides real-time, three-gauge feedback, ensuring precision, maximizing uptime, and protecting your critical production equipment.
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![GettyImages-1266602356-Powder Inhaler Patient]( "Navigating The Development Of Dry Powder For Inhalation")
Navigating The Development Of Dry Powder For InhalationA CDMO-authored framework for navigating dry powder inhaler development, covering target product profile definition, API characterization, particle engineering technology selection, and encapsulation considerations.
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![GettyImages-1465073074 tablets, OSD, pills]( "Improving Stability Through Science-Led OSD Reformulation")
Improving Stability Through Science-Led OSD ReformulationA marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.
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Optimising Solubility: Selecting The Right Technology For Early Drug Development5/6/2026
Discover how selecting the right solubility‑enhancing technology improves early exposure, supports flexible dosing, and lays a strong foundation for downstream oral drug development.
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Why Spray Drying Is Gaining Attention7/20/2026
Facing patent cliffs, pharma companies can leverage spray drying to reformulate complex biologics, enabling non-invasive delivery, boosting patient convenience, and securing new patents.
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Minitablets: Enhancing Safety And Palatability For Pediatric Medicines1/15/2026
Leverage minitablet technology to create flexible, easy-to-swallow, and palatable pediatric formulations that improve adherence and meet evolving regulatory requirements.
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How To Fast-Track Your Oral Solid Dose To Phase 12/17/2026
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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Ask Us Anything: Jillian Sheeran On Emerging Reactor Technologies7/23/2026
Jillian Sheeran, Associate Director of Engineering at Snapdragon Chemistry, on how automation, feedback control, and machine learning are changing reactor design — with real-time monitoring that lets a process run continuously while the data comes to you.
SOLID DOSE MANUFACTURING SOLUTIONS
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![5089-7-01]( "Used Marchesini Thermoformer / Cartoner")
Used Marchesini Thermoformer / Cartoner
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![30 Vector Hi-Coater Coating Pan]( "Used 30\" Vector Hi-Coater Tablet Coating Pan")
30" Vector Hi-Coater Coating Pan, stainless steel construction, for model VHC-1355 coater, built 2002.
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![PTS Powder Transfer]( "PTS Powder Transfer System®: Dense Phase Powder Conveying")
PTS Powder Transfer System® challenges convention by using both vacuum and pressure to move powders as if they were liquids. This eliminates the need for gravity charging and therefore making multi floor processes a requirement of the past.
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![iStock-870087778-powder]( "Powder Flow Properties & Characterization Services")
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
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![GettyImages-157742535 molecule pfas]( "Build Your Solution: Not Every Molecule Follows A Manual")
A flexible, data‑driven development approach assembles tailored scientific strategies around each molecule, reducing risk, improving manufacturability, and enabling scalable formulation solutions.
