INSIGHTS ON SOLID DOSE MANUFACTURING
-
Navigating OSD Formulation Development And Leveraging CDMO Partnership
Collaborating with an experienced CDMO can provide the expertise and facilities needed to navigate oral solid dose formulation complexities and ensure compliance with regulatory frameworks.
-
Integration From Formulation Development To Manufacturing, Packaging
Adare Pharma Solutions' Pessano, Italy facility offers 220,000 sq. ft. of end-to-end services, including R&D, formulation development, clinical and commercial manufacturing, packaging, and advanced analytical capabilities.
-
Rheological Properties Of Pharmaceutical Excipients: Lactose Monohydrate And Carboxymethyl Cellulose
Explore lactose monohydrate and CMC rheology, highlighting their flow, cohesion, and compressibility properties to optimize pharmaceutical formulations under varying stress and temperature conditions.
-
M6 Tablet Metal Detector For Pharmaceutical And Nutraceutical Production
Ensure the safety and quality of your tablets and capsules with a metal detector designed for stability and high sensitivity in pharmaceutical and nutraceutical production.
-
Taste-Masked Dosage Forms For Pediatric Oral Delivery: An Industrial Perspective7/18/2024
Leveraging strategies and technologies for pediatric patient compliance for taste masking and controlled release in pharmaceutical products, enables flexibility in dosage and format options.
-
Improving API Solubility Using Hot Melt Extrusion Formulation2/27/2025
Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
-
Raise Your Standards With Downflow Booth Airflow Containment1/30/2026
Ensure personnel safety during hazardous material handling by mastering airflow dynamics and containment screens. Learn to achieve low exposure levels through advanced HEPA filtration methods.
-
The Future Of Oral Solid Dose Development And Innovation2/27/2025
Tom Sellig, CEO of Adare, discusses the ongoing relevance of small molecules, oral solid dose development, trends like GLP-1, and innovations like 3D printing in pharmaceuticals.
-
Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives7/17/2024
A gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.
SOLID DOSE MANUFACTURING SOLUTIONS
-
Natoli’s line of efficient tablet presses combine remarkable tablet production, automation and dependability.
-
Natoli Scientific offers manufacturing services of oral solids at a pilot scale and drug products for clinical trials.
We also offer full-scale commercial manufacturing service till you are ready with your own manufacturing facility to avoid delay in the commercial launch.
Team Natoli understands the complexity of the tablet manufacturing process over more than half a century. We are ready to shoulder every step of the tablet manufacturing chain from blending to granulation, to milling, to compression, to coating. Our manufacturing capabilities are backed up by our expert scientific team, who are ready to offer guidance in product development, technical transfers, and scale-ups.
-
ROSS Dual Shaft Mixers are durable, versatile systems designed for precise processing of high-performance formulations across diverse rheologies, solids loading, temperatures, and pressures.
-
Dec offers filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.
-
Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.