INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-1465073074 tablets, OSD, pills]( "A Powerful Non-Destructive Tool For Tablet Characterization")
A Powerful Non-Destructive Tool For Tablet CharacterizationDiscover how X-ray micro-CT provides vital, non-destructive analysis of a tablet’s internal 3D physical structure. This structural insight is essential for troubleshooting defects and confirming performance.
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![Question-Pills-Hand]( "Head Pressure In Your Hopper: What Is It, And How Do You Mitigate It?")
Head Pressure In Your Hopper: What Is It, And How Do You Mitigate It?What is head pressure in your hopper and how does it relate to tablet press performance?
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![Bora Pharmaceuticals - Zhunan Facility Site VR Tour]( "Zhunan Facility Site VR Tour")
Zhunan Facility Site VR TourBora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
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![Scientist-with-tablet-GettyImages-950594528]( "Barrel-Style vs. Standard Dust Cups vs. Bellows: The Essentials Behind Producing The Highest Quality Tablets Free From Contaminates")
Barrel-Style vs. Standard Dust Cups vs. Bellows: The Essentials Behind Producing The Highest Quality Tablets Free From ContaminatesDust cups and bellows are essential components in tablet manufacturing, utilized to prevent lubricants from contaminating the tablets.
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing6/30/2025
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
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Smart Softgels: Driving Innovation In Pharma7/29/2024
Learn about how softgels are poised to facilitate innovation in the pharmaceutical industry as well as ongoing advancements in optimizing drug bioavailability through nano formulations.
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Developing And Manufacturing Minitablets To Extend Drug Lifecycle1/27/2025
Pharmaceutical companies should leverage oral minitablets to extend drug lifecycles, optimize dosing, and improve patient-centric solutions while overcoming manufacturing challenges.
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers10/7/2025
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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An Alternative Method Of Drug-Excipient Characterization12/30/2024
Isothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.
SOLID DOSE MANUFACTURING SOLUTIONS
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![GettyImages-1216446418_pellets]( "Multiparticulates For Modified Release Systems")
Multiparticulates enable tailored drug release with improved flexibility, dose accuracy, and patient convenience, leveraging technologies like Diffucaps® for customized profiles including immediate, delayed, extended, and pulsatile delivery.
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![60 OHara FastCoat Coating Pan]( "Used O'Hara Pharmaceutical Tablet Coating Pan: FC400")
Used 60" O'Hara FastCoat coating pan, model FC400 (60xc5), stainless steel construction with 60" diameter perforated Pan, solvent rated design, O'Hara advanced controls with Allen Bradley Compact Logix PLC, PC and HMI units, O'Hara manifold with Schlick nozzle spray arm, built in Watson Marlow peristaltic pump with Micromotion mass flow and recirculation system, reverse pan unloading, outdoor rated air handling unit (AHU) with preheat steam coil, chilled water dehumidification unit, steam reheat with face/bypass temp control dampers, HEPA module, Camfil DCU with FIKE suppression and isolation system, bag in bag out with exhaust HEPF module, 480 volt, system serial# 4501, built 2020.
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![Pharmaceutical-isolator]( "Pharmaceutical Isolator From Franz Ziel")
Personal protection pharmaceutical isolators enables personal protection for operators when handling toxic substances.
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![AST innovation]( "A User-Friendly Solution For Fill-Finish Professionals")
When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
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![Natoli AIM™ Data Acquisition & Analytical Software for the NP-RD10A Tablet Press]( "Natoli AIM™ Data Acquisition & Analytical Software for the NP-RD10A Tablet Press")
Natoli Engineering now offers AIM™ Data Acquisition & Analytical Software for the Natoli NP-RD10A research and development tablet press. The combination of AIM™ Software and this R&D tablet press enables the researcher to evaluate formulation properties and identify potential tableting issues—including capping, lamination, sticking/picking, and tablet robustness—during the tablet development process. Plus, the software can optimize tablet tensile strength and lubrication for successful large-scale manufacturing production.
