INSIGHTS ON SOLID DOSE MANUFACTURING
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Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers
Tablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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Head Pressure In Your Hopper: What Is It, And How Do You Mitigate It?
What is head pressure in your hopper and how does it relate to tablet press performance?
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How To Address Your Solid Dosage Processing Needs
Unlock the keys to consistent solid dosage products. Learn to align unique product needs with optimal processing requirements and equipment strategies. Gain a roadmap for improved quality and reproducibility.
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Liquid Suspension Trends In The CDMO Space
Liquid suspension formulations are rapidly growing in pharma, driven by patient needs, formulation advances, and CDMO innovation.
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How To Solve Complex Pediatric Dosing Challenges Using Tailored Solutions8/11/2025
With a partner who understands the science, the regulations, and the real-world demands of dosing children, development can move faster, smarter, and with greater confidence
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Developing And Manufacturing Drugs With HPAPIs1/27/2025
Learn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.
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Integration From Formulation Development To Manufacturing, Packaging2/27/2025
Adare Pharma Solutions' Pessano, Italy facility offers 220,000 sq. ft. of end-to-end services, including R&D, formulation development, clinical and commercial manufacturing, packaging, and advanced analytical capabilities.
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Solubility Enhancement Via Amorphous Solid Dispersions2/27/2025
Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
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Die Bore Cracking: How To Achieve Reliable Tablet Production7/30/2024
Die bore cracking is a significant issue in tablet manufacturing, affecting the quality of the tablets and potentially damaging the tablet press. Explore how to analyze for and prevent this damage.
SOLID DOSE MANUFACTURING SOLUTIONS
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Explore a mid-sized tablet press designed with optional features including force monitoring, a power rotary forced feeder, a tablet reject chute, and a hopper vibration unit.
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Used ThermoScientific Haake Pelletizing line, with model Phama 11 HME twin screw extruder, item# 553-0020, co-rotating screws, 40:1 l/d, 1000 rpm screw speed, 1.5 kw motor drive, with feeder, and operator HMI touchscreen. ThermoScientific Ph11 Conveyor, item# 553-0600, serial# 1-21004125001. ThermoScientific pelletizer, 6 blade rotor with pull roll, 230 volt, CE design, extruder machine# KU18-000011, serial# 1-1800319001, built 2019.
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Capsugel Xcelodose 600 Capsule Filler with Xcelotable, CE rated, serial# 600-1-039.
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Used 19 MM APV Baker Perkins twin screw co rotating extruder, model MP-19-TC, 19 mm diameter screws, 40:1 l/d, electrically heated, water cooled barrel, split barrel design, 2 kw dc motor, 500 rpm screw spped, with Ktron main feeder, (2) Brabender auxiliary feeders, (3) Zenith melt pumps, FTS chiller, external control panel, with associated screws, screw elements, control panel, 220 volt, CE rated, APV serial# NEF990028-701/1, Baker Perkins serial# TS99535, project# 99TS196, built 1999.
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Natoli Quick-Release Tablet Tooling allows researchers to test different dwell times during the tablet R&D process without the expense of buying several different sets of tools or the time needed to change complete sets of tooling or turret speed.