INSIGHTS ON SOLID DOSE MANUFACTURING
-
Innovative ASD Technology Improves Abandoned Cancer Medication
Review this case to learn how one solid dispersion technology lowered patients' pill burdens and demonstrated an improved therapeutic response for Galeterone.
-
M6 Tablet Metal Detector For Pharmaceutical And Nutraceutical Production
Ensure the safety and quality of your tablets and capsules with a metal detector designed for stability and high sensitivity in pharmaceutical and nutraceutical production.
-
Less Mess, Less Stress, Best Expressed: An Alternative To Spray Drying
Although well-established processes, spray drying and hot-melt extrusion can be outperformed in bioavailability, cost-savings, manufacturing speed, environmental impact, and more.
-
A Powerful Non-Destructive Tool For Tablet Characterization
Discover how X-ray micro-CT provides vital, non-destructive analysis of a tablet’s internal 3D physical structure. This structural insight is essential for troubleshooting defects and confirming performance.
-
Challenges Associated With Building New Isolator Technology3/26/2024
Paula Rizo, Germfree’s Mechanical Engineering Lead for Equipment, dives deeper into our collaboration with AST and how this isolator technology will transform the way pharmaceutical companies approach aseptic processing.
-
Patient Adherence with A Novel Dosage Form11/13/2025
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
-
Orally-Disintegrating Dosage Forms With Taste Masked Multiparticulates7/17/2024
Learn more about our orally disintegrating tablet (ODT) capabilities and how these innovative technologies have the potential to improve acceptance, adherence, and compliance in pharmacotherapy.
-
Developing And Manufacturing Drugs With HPAPIs1/27/2025
Learn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.
-
Customized Release Through Dispersed Dosage Formats6/13/2024
Typically, dosage format is based on the target product profile: how the developer envisions the product best addressing a clinical indication by maintaining population-wide efficacy.
SOLID DOSE MANUFACTURING SOLUTIONS
-
A global leader in manufacturing, Natoli Engineering Company delivers superior tablet compression tooling. Every punch and die is produced from quarantined steel and tested for hardness and exact chemical composition by stringent quality specifications.
-
Used Fitzpatrick Chilsonator roller compactor, model 1.5LX8D, with 8" diameter x 1.5" wide grooved rolls, vertical and horizontal pre-compression screws, serial# 489.
-
Flexible Containment Isolators provide containment standards better than can be achieved with Downflow Booth technology, and often compare favorably with a Rigid Isolator system.
-
Used IMA Zanasi 6 F Capsule Filler, rated up to 6000 capsules/hour, no change parts, capable of producing 00-5 size capsules, with controls and Siemens PLC, 230 volt, 3 phase, serial# 35071, built 2006.
-
Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.