INSIGHTS ON SOLID DOSE MANUFACTURING

• Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability

  Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.

• Benefits Of Isolator Technology In Fill-Finish

  Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations.

• Innovations, Solutions, And USP <1062> With Scale Up

  Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.

• Tablet And Capsule Inspection: Detecting Defects Before They Ship

  Inline X-ray inspection identifies density variations and foreign contaminants in solid dose products to prevent costly recalls and ensure strict quality compliance.

• GLP-1 OSD Chemical Synthesis Workflow

  6/29/2026

  Enhance containment and process reliability in oral GLP-1 synthesis. Discover how integrated single-use assemblies and automated fluidics safeguard chemical purity during scale-up.

• Overcoming The Obstacles Of Spray-Dried Dispersion Scale-Up

  9/9/2026

  SDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.

• Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling

  7/15/2026

  Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.

• Powder Rheology: Gateway For Tablet Sticking Insights

  10/7/2025

  Powder rheology offers a scientific method to predict and mitigate tablet sticking issues, helping to ensure smoother pharmaceutical production cycles through early material and tooling selection.

• Decontamination Of Aseptic Pharmaceutical Isolators Using Vaporized And Aerosolized Hydrogen Peroxide

  8/26/2026

  Aerosolized hydrogen peroxide decontamination cuts isolator cycle times from 70 to 15 minutes while drastically reducing biocide and overall energy usage.