INSIGHTS ON SOLID DOSE MANUFACTURING

• HPAPIS Production: "Where Micrograms Matters"

  In HPAPI manufacturing, micrograms make a difference. Risk‑based containment, smart facility design, and exposure limits safeguard people, product, and performance.

• Automated Precision Powder Filling For Annex 1

  Aseptic powder filling is complex, demanding automation and isolator‑based, weight‑controlled dosing to ensure sterility and accuracy.

• Engineering Challenges Of Designing Pharmaceutical Isolators

  Designing pharmaceutical isolators requires navigating complex engineering hurdles, from ensuring chemical compatibility to optimizing airflow and pressure. Explore the critical considerations that guarantee drug manufacturing safety and efficiency.

• Improving API Solubility Using Hot Melt Extrusion Formulation

  Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.

• Patient Adherence With A Novel Dosage Form

  11/13/2025

  A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.

• The Future Of Sustainable Amorphous Dispersion Development

  4/15/2026

  Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.

• Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months

  2/26/2026

  A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.

• High Potency APIs And The Evolving Demands Of Drug Development

  4/13/2026

  See how higher API activity is changing expectations around containment, scalability, and cross‑functional alignment — and why early decisions now have a greater impact on long‑term success.

• Ask Us Anything: Daniele Vigo On Cost-Effective Process Development

  7/23/2026

  Daniele Vigo, Assistant Director at Cambrex Milan, on getting yield, purity, and scalability right without burning through the budget.