INSIGHTS ON SOLID DOSE MANUFACTURING
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![Dalton photo 1]( "Automated Precision Powder Filling For Annex 1")
Automated Precision Powder Filling For Annex 1Aseptic powder filling is complex, demanding automation and isolator‑based, weight‑controlled dosing to ensure sterility and accuracy.
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![Decontamination of aseptic pharma dec pic 1]( "Decontamination Of Aseptic Pharmaceutical Isolators Using Vaporized And Aerosolized Hydrogen Peroxide")
Decontamination Of Aseptic Pharmaceutical Isolators Using Vaporized And Aerosolized Hydrogen PeroxideAerosolized hydrogen peroxide decontamination cuts isolator cycle times from 70 to 15 minutes while drastically reducing biocide and overall energy usage.
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![Adapting (2)]( "Adapting To Evolving Needs: How Modular Cleanrooms Enhance Safety In Pharmaceutical Manufacturing")
Adapting To Evolving Needs: How Modular Cleanrooms Enhance Safety In Pharmaceutical ManufacturingHigh-potency therapies demand stringent containment and worker safety. Discover how scalable, modular infrastructure simplifies compliance and protects product integrity in regulated facilities.
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![GettyImages-498013412-laboratory-flask-water-solubility-dropper]( "Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement Strategies")
Improving Bioavailability Through Predictive Modeling Of Solubility Enhancement StrategiesIn silico modeling cut through formulation guesswork for a compound with 0.015 mg/mL solubility, delivering an 8× Cmax and 5× AUC improvement and Phase I progression.
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Benefits Of Isolator Technology In Fill-Finish12/10/2025
Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations.
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5 Hidden Risks In Early-Phase OSD Formulation Development8/31/2026
Early formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.
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Liquid Suspension Trends In The CDMO Space1/15/2026
Liquid suspension formulations are rapidly growing in pharma, driven by patient needs, formulation advances, and CDMO innovation.
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Benefits Of Single-Use Isolators For Cytotoxic Payload Handling6/15/2026
Managing cytotoxic ADC payloads in shared containment facilities creates mounting compliance, safety, and operational costs that single-use isolator technology is designed to address.
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How To Achieve Late-Phase Success In Complex OSD Development8/31/2026
Late-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Open-Restricted-Access-Barrier-System]( "Open Restricted Access Barrier System (RABS) From Franz Ziel")
Open RABS as a housing for aseptic processes, e.g., filling, loading, and unloading of freeze dryers. Product protection is achieved by a barrier (oRABS housing with gloves) between the operator and the product.
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![4532-25-01]( "8 Sq Meter Rosenmund Filter Dryer, 304L S/S, 50/150#")
Used 8 sq meter Rosenmund filter dryer, 304L stainless steel construction, rated 50 psi and full vacuum internal at 350 f, jacketed for 150 psi and full vacuum at 350 f, cored 3 wing agitator with rotary union driven by 40 hp motor drive, 460 volt, side discharge with plug valve, includes APOVAC vacuum recovery system, model APOVAC 3817, with Sulzer Burckhardt vacuum pump, condensor and receiver tank, hydraulic power pack, Filter certified by Paul Mueller Co, serial# 170084, national board# 25763, Rosenmund serial# RSD8-886-96, built 1996.
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![Dec Group 2]( "Production-Scale Pharmaceutical Filling Systems")
Dec‘s philosophy is to develop customer-specific modules and equipment. Starting with agreed project scope, intensive brainstorm sessions, strong design processes and (customer) reviews, the aim is to deliver an innovative filling solution. During the concept development, risk analysis is an important tool in the decision-making process.
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![Big Bag Pharma]( "Big Bag Pharmaceutical Filling System For Drums, Boxes, Flexible IBC's")
If you handle multiple packaging, Dec can help in providing one single multi-packaging filling station handling FIBCs, drums, cardboard boxes etc.).
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![Pharmaceutical Filling Systems.jpg]( "R&D Pharmaceutical Filling Systems: Powder And Liquid")
If you are looking for filling systems for different products such as liquids, powder or flow-resistant highly viscous materials, Dec provides a modular concept allowing to meet a variety of packaging that is appropriate in the field of research and development as well as clinical trials. Speed up your go-to-market strategy with innovation and modular thinking.
