INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-1266602356-Powder Inhaler Patient]( "Navigating The Development Of Dry Powder For Inhalation")
Navigating The Development Of Dry Powder For InhalationA CDMO-authored framework for navigating dry powder inhaler development, covering target product profile definition, API characterization, particle engineering technology selection, and encapsulation considerations.
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![HPAPIS Production Where Micrograms Matters]( "HPAPIS Production: \"Where Micrograms Matters\"")
HPAPIS Production: "Where Micrograms Matters"In HPAPI manufacturing, micrograms make a difference. Risk‑based containment, smart facility design, and exposure limits safeguard people, product, and performance.
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![Tablet Logo Legibility]( "Tablet Logo Legibility: A Critical Component Of Consumer Health")
Tablet Logo Legibility: A Critical Component Of Consumer HealthOptimizing tablet debossing geometry balances regulatory legibility standards with compression efficiency, preventing sticking, picking, and film coating defects.
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![GettyImages-1417391937-pharmaceutical-spray-drying-with-scientists]( "Overcoming The Obstacles Of Spray-Dried Dispersion Scale-Up")
Overcoming The Obstacles Of Spray-Dried Dispersion Scale-UpSDD scale-up introduces scale-dependent risks that threaten bioavailability, stability, and manufacturability. This white paper details a model-based framework for managing those risks from early feasibility through commercial production.
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Reconstitutable Powder Filling System For Global MedTech Client9/3/2026
Custom automated powder dosing platforms streamline dual-powder aseptic device assembly, achieving high-speed precision and robust containment control
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Innovations, Solutions, And USP <1062> With Scale Up11/4/2025
Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
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Ask Us Anything: Eric Fang On Lithiation Chemistry7/24/2026
Eric Fang, General Manager of Snapdragon Chemistry, on why lithiation chemistry resists batch scale-up — and how a decade spent understanding static mixing lets Snapdragon carry these reactions from milligrams to metric tons.
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Imprints On Oral Solid Dosage Forms9/28/2026
Selecting the right tablet imprinting technology is essential for product identification and compliance. Improve your print clarity, speed, and overall manufacturing efficiency.
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Improving API Solubility Using Hot Melt Extrusion Formulation2/27/2025
Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Aseptic-processing-isolator]( "Aseptic Processing Isolator (Filling-Lyophilization) From Franz Ziel")
Isolators with product protection as a housing for aseptic processes, e.g. filling, loading and unloading of freeze dryers.
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![Esco-Pharmcon Downflow Booth Gen 2 (DFBG2)]( "Customizable Downflow Booths")
Ensure operator safety and product purity with unidirectional airflow solutions. Explore how modular ISO 5 environments provide containment and cross-contamination control for critical processes.
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![Used Shionogi Qualicaps Capsule Checkweigher System]( "Used Shionogi Qualicaps Capsule Checkweigher System")
Used Shionogi Qualicaps capsule checkweigher, model CWI-40, nominally rated up to 40000 capsules/hour throughput, with weigh check option, capsule reject system, stainless steel feed hopper, includes size 00, 0, 1, 2, 3, and 4 change parts with HMI touchscreen, serial# S0053, built 2004.
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![Pharmaceutical IMA Tablet and Capsule Checkweigher]( "Used Pharmaceutical IMA Tablet and Capsule Checkweigher: Precisa 18")
Used IMA Precisa 18 tablet/capsule checkweigher. Made in 2003. Size 2 change parts. With Becker vacuum pump. S/N: PA1099.
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![iStock-870087778-powder]( "Powder Flow Properties & Characterization Services")
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
