INSIGHTS ON SOLID DOSE MANUFACTURING
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Layer By Layer: 3D Screen Printing And The Future Of Drug Development
3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.
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Minitablets: Enhancing Safety And Palatability For Pediatric Medicines
Leverage minitablet technology to create flexible, easy-to-swallow, and palatable pediatric formulations that improve adherence and meet evolving regulatory requirements.
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How To Fast-Track Your Oral Solid Dose To Phase 1
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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Improving API Solubility Using Hot Melt Extrusion Formulation
Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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Navigating High-Potency OSD Manufacturing4/13/2026
Learn how containment strategy, process design, and early risk‑based decisions influence operator protection, compliance, and long‑term manufacturing success as potency levels continue to rise.
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Low-Bioburden Powders For Terminal Sterilisation2/24/2026
Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
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Harnessing Digital Twins To Optimize Tablet Manufacturing10/30/2025
Unlock manufacturing precision with digital twins. Learn how virtual replicas of production systems enable predictive maintenance, streamline scale-up, and ensure consistent product quality in pharma.
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Barrel-Style vs. Standard Dust Cups vs. Bellows: The Essentials Behind Producing The Highest Quality Tablets Free From Contaminates7/30/2024
Dust cups and bellows are essential components in tablet manufacturing, utilized to prevent lubricants from contaminating the tablets.
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Bottling Solutions3/4/2025
Explore a bottling solution that is meticulously engineered to adhere to the most stringent pharmaceutical standards, which guarantees that each product is crafted with unparalleled quality and precision.
SOLID DOSE MANUFACTURING SOLUTIONS
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Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.
With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.
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ROSS Dual Shaft Mixers are durable, versatile systems designed for precise processing of high-performance formulations across diverse rheologies, solids loading, temperatures, and pressures.
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Dec provides unique solutions to charge process equipment such as reactors, mixing vessels or dryers in a fully safe manner eliminating the need to connect the isolator directly to the equipment to be charged or to install the isolator on an upper floor. A single isolator system can be used for multiple vessels charging.
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Sterility testing isolators with product protection for the sterility test under aseptic and optionally aseptic/toxic conditions. A Rapid Decon Hatch (RDH) can be connected as an option.
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Used Sejong rotary tablet press, model GRC-15C, 15 station, D tooled, 6 kn main compression, 2 kn pre compression, 25 mm max tablet diameter, 22 mm max depth of fill, with feed hoppers, rated up to 67500 tablets/hour, with integrated controls and touchscreen interface, serial# ST17866, built 2017.