INSIGHTS ON SOLID DOSE MANUFACTURING
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Predicting Drug-Loading Limits In Tablet Formulations
Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
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Solubility And Improved Patient Outcomes
Poor solubility poses major development challenges. Innovative formulation technologies and careful excipient selection can improve bioavailability and product performance.
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
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When To Consider Material And Personnel Airlocks For Downflow Booths
Strategic use of airlocks in downflow booth design enhances pressure stability and containment. A risk-based approach ensures facility integration meets rigorous safety and compliance standards.
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Scaling Spray-dried Dispersions For Commercial Success: Scale, Capacity, Supply10/26/2026
Scaling SDDs takes more than larger batches. Explore how early planning and process understanding can preserve performance and reduce commercialization risk.
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Maximize Uptime And Yield With This Feeder Base Leveling System10/8/2025
Learn how a patented leveling system provides real-time, three-gauge feedback, ensuring precision, maximizing uptime, and protecting your critical production equipment.
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Navigating High-Potency OSD Manufacturing4/13/2026
Learn how containment strategy, process design, and early risk‑based decisions influence operator protection, compliance, and long‑term manufacturing success as potency levels continue to rise.
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Cytiva's Aseptic Filling Workcell User Group1/9/2026
Discover how global collaboration among aseptic filling experts is driving innovation and improving operations.
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Precision In Miniature: Optimizing Multiparticulate Formulations For Pediatric Oncology9/9/2026
When an oral liquid formulation of crizotinib failed pediatric trials due to intolerable taste and irritation, a multiparticulate approach offered a technically demanding but viable path forward.
SOLID DOSE MANUFACTURING SOLUTIONS
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The mixer is loaded with the individual raw materials exactly according to the formulation. The combination of Dosicon® weighing equipment with suction conveying units fulfils this task. Fundamental advanrages of JetSolutions automatic multi-component dosing are high dosing accuracy (for quantities ranging from a few hundred grams to several hundred kilos), the prevention of cross-contamination risks, and freedom from dust.
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Active pharmaceutical ingredient (API) manufacturing requires powder handling in a GMP and contained manner. Similar to chemical manufacturing, operations like charging powders into a chemical reactor, emptying a centrifuge or charging and discharging a dryer are standard processes.
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Scalable capsule filling systems streamline product development from lab testing to production. See how interchangeable dosing modules handle precise combinations of powders, liquids, and more.
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Handling highly potent active pharmaceutical ingredients calls for containment systems that protect operators while maintaining strict OEL thresholds below 0.1 μg/M3 throughout every transfer step.
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Integrated global small‑molecule development and manufacturing solutions spanning chemistry, analytics, scale‑up, and commercial API supply, designed to reduce CMC risk and accelerate progress.