INSIGHTS ON SOLID DOSE MANUFACTURING
-
Successful Tech Transfer Plans Ensured On-Time Launches
Successful technology transfers require proactive engineering and rigorous assessments to address equipment challenges, protect product integrity, and keep launches on schedule.
-
Improving Stability Through Science-Led OSD Reformulation
A marketed multivitamin tablet spanning a 0.03% to 46% w/w range failed early in accelerated stability testing. Mechanism-led reformulation and a switch to direct compression changed the outcome.
-
Layer By Layer: 3D Screen Printing And The Future Of Drug Development
3D screen printing can produce tablets across a range of release profiles, from conventional immediate release tablets to multi-compartment drug delivery systems that mix different release profiles.
-
Low-Bioburden Powders For Terminal Sterilisation
Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
-
Seamless Commercial Tech Transfers In OSD Manufacturing9/9/2026
A structured approach to OSD tech transfer, from NPI through PPQ and CPV, can compress timelines significantly, as one case study illustrates with full PPQ completion in under six months.
-
Segments: Next-Generation Tablet Press Technology10/7/2025
Segments increase press output by up to 25% and cut setup time by 88%. Learn the benefits, drawbacks, and manufacturing needs of this rapidly growing tablet press technology.
-
How To Handle Intrinsic Product Powder Particles3/16/2026
Powder filling creates intrinsic particles that interfere with continuous monitoring. Risk‑based strategies must separate product dust from true contamination to meet Annex 1 requirements.
-
Predicting Drug-Loading Limits In Tablet Formulations7/15/2026
Learn how predictive percolation modeling identified critical drug-loading limits of ~20% for crystalline API and ~15% for SDD forms, cutting tablet formulation trial-and-error significantly.
-
Ask Us Anything: Mark Benger On Solid-State Strategies For Drug Development7/23/2026
Mark Benger, Site Director at Cambrex Edinburgh, on solid-state characterization as an insurance policy — front-loaded work that quietly determines whether a program survives the jump from kilos to tonnes.
SOLID DOSE MANUFACTURING SOLUTIONS
-
Custom primary blistering solutions for pharmaceutical, nutraceutical, and animal health oral solid dose. Providing standard Unit Dose (HUD) and bingo style blister packs with thermoform and cold-form capabilities.
-
Containment is a major concern for GMP industries. With a proven track record in managing highly technical and challenging isolation projects Dec is the perfect partner for the integration of new or existing equipment by providing comprehensive safe, ergonomic and dedicated containment solutions.
-
Maintain peak safety and sterility in sensitive environments with advanced isolation technology. Ensure strict compliance and reliable protection during critical, high-stakes processing tasks.
-
Integrated powder containment, fluid handling, and gas utility systems streamline biomanufacturing. Simplify compliance and protect uptime across your end-to-end processing operations.
-
The aseptic/sterile Fill-Finish equipment solutions need to be cGMP compliant, dependable and accurately designed to comply with the most recent revisions of the “Annex 1 Manufacture of Sterile Medicinal Products guidelines”. Newly designed equipment needs to accommodate for small batches, various speeds and containers, including RTU / RTF (Ready To Use or Ready To Fill) bottles, vials, cartridges, syringes and pre-sterile nested trays. Moreover, the filling equipment solution should also improve the ergonomic use for operators and maximize cleanroom efficiency.