Solid Dose Manufacturing

INSIGHTS ON SOLID DOSE MANUFACTURING

High Potency APIs And The Evolving Demands Of Drug Development
See how higher API activity is changing expectations around containment, scalability, and cross‑functional alignment — and why early decisions now have a greater impact on long‑term success.
How To Solve Complex Pediatric Dosing Challenges Using Tailored Solutions
With a partner who understands the science, the regulations, and the real-world demands of dosing children, development can move faster, smarter, and with greater confidence
Maximum Protection With Superior Quality
See how this automated capsule filling technology integrates high-containment isolators and 100% inline checkweighing to ensure precise dosing, operator safety, and continuous quality control
Predicting Softgel Stability And Shelf Life Using Accelerated Modeling
Predict ibuprofen softgel shelf life in 21 days instead of years. ASAPprime modeling identified PEG-ester degradants as the limiting factor, estimating 5.5-year and 3.8-year shelf lives before long-term studies concluded.

Modern Containment Solutions In OSD Processes
6/15/2026

Outdated containment infrastructure in OSD facilities creates costly compliance gaps and operational bottlenecks. Flexible single-use isolator systems offer a faster, more adaptable path forward.
Practical Formulation Strategies For Poorly Soluble APIs
10/2/2026

Poor aqueous solubility now defines most drug candidates in development, making early screening and solid-state assessment essential to achieving reliable exposure and avoiding costly reformulation downstream.
Innovations, Solutions, And USP <1062> With Scale Up
11/4/2025

Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
Navigating The Development Of Dry Powder For Inhalation
9/9/2026

A CDMO-authored framework for navigating dry powder inhaler development, covering target product profile definition, API characterization, particle engineering technology selection, and encapsulation considerations.
How High Drug Load Nanocrystalline Tablets Lower Pill Burden
3/12/2025

We showcase the development of high drug load nanocrystal based tablets and prove that nanocrystals can match the pharmacokinetic performance of ASDs while reducing the overall pill burden.

Drug Product Manufacturing

GMP drug product manufacturing supports solid dose and sterile parenteral development with formulation expertise, isolator fill‑finish, DEA‑licensed work, packaging, labeling, and supply‑chain services.
Loading And Charging Of Drums For High Potent API's: IsoTube

Isotube is an effective option for the safe loading and charging of multiple drums of HPAPIs. Compared to the DCS® Drum Containment System for safely discharging drums, it is the preferred choice when charging lumpy and agglomerated products as a lump breaker system can be included in the lower part of the discharge hopper.
Big Bag Pharmaceutical Filling System For Drums, Boxes, Flexible IBC's

If you handle multiple packaging, Dec can help in providing one single multi-packaging filling station handling FIBCs, drums, cardboard boxes etc.).
Powder Rheology Accessory

The Powder Rheology Accessory expands the DHR’s capabilities to powders, enabling the characterization of behaviors during storage, dispensing, processing, and end-use.
Capsule Filling And Weighing

Scalable capsule filling systems streamline product development from lab testing to production. See how interchangeable dosing modules handle precise combinations of powders, liquids, and more.