INSIGHTS ON SOLID DOSE MANUFACTURING
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Developing And Manufacturing Drugs With HPAPIs
Learn why companies must invest in specialized expertise to develop scalable, safe, and efficient manufacturing processes for highly potent oral solid dose products.
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Advances In Oral GLP-1 Analogs For Obesity
Discover how these groundbreaking Oral GLP-1 Analogs therapies are reshaping obesity management and addressing key challenges in formulation and delivery.
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Maximize Uptime And Yield With This Feeder Base Leveling System
Learn how a patented leveling system provides real-time, three-gauge feedback, ensuring precision, maximizing uptime, and protecting your critical production equipment.
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Solubility Enhancement Via Amorphous Solid Dispersions
Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
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Solvent-Free, Fusion-Based Amorphic Dispersion Process7/11/2024
Discover a solvent-free, fusion-based process that leverages frictional and shear forces to rapidly convert crystalline drugs and polymers into amorphous solid dispersions (ASDs).
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Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months2/26/2026
A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
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Segments: Next-Generation Tablet Press Technology10/7/2025
Segments increase press output by up to 25% and cut setup time by 88%. Learn the benefits, drawbacks, and manufacturing needs of this rapidly growing tablet press technology.
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The Future Of Pharma Packaging Trends, Technologies, And Patient-Centric Solutions4/14/2026
Pharmaceutical packaging must evolve alongside drug development to ensure stability, safety, and regulatory adherence, utilizing innovative designs to improve therapeutic outcomes and patient accessibility.
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing6/30/2025
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
SOLID DOSE MANUFACTURING SOLUTIONS
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Maintain peak safety and sterility in sensitive environments with advanced isolation technology. Ensure strict compliance and reliable protection during critical, high-stakes processing tasks.
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Used BWI Manesty Unipress Diamond rotary table press, 27 station, keyed upper punch guides, 6.5 ton main compression, 1 ton pre compression, B tooled, 16 mm max tablet diameter, 18 mm max depth of fill, single side with force feeder with feed hopper, rated up to 196,200 tablets/hour, serial# UN248JA.
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Capsugel Xcelodose 600 Capsule Filler with Xcelotable, CE rated, serial# 600-1-039.
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Used Korsch rotary tablet press, model PH250/25, 25 station, 20 Kn pre compression, 80 Kn main compression, 16 mm max tablet diameter, 18 mm max depth of fill, single side with force feeder, rated up to 180000 tablets/hour, serial# 1.0031.94, built 1994.
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Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.