INSIGHTS ON SOLID DOSE MANUFACTURING
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Navigating High-Potency OSD Manufacturing
Learn how containment strategy, process design, and early risk‑based decisions influence operator protection, compliance, and long‑term manufacturing success as potency levels continue to rise.
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An Alternative Method Of Drug-Excipient Characterization
Isothermal microcalorimetry (IMC) rapidly screens API-excipient compatibility, detecting physical and chemical interactions faster than conventional methods, saving time and effort in pharmaceutical formulation development.
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Advancing Patient-Centric Drug Delivery For Neurodegenerative Disease With Orally Dissolving Tablets
Pharmaceutical companies must prioritize patient-centric dosage forms to address challenges like dysphagia, enhance medication compliance, and improve therapeutic outcomes.
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Global Regulatory Harmonization: Comparisons In Aseptic Barrier Systems
Compare global aseptic standards from the FDA, EMA, PIC/S, and WHO. Gain insights into how advanced barrier systems harmonize international requirements to ensure sterile product integrity and safety.
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Exploring The Future Of Tablet Compression Across Emerging Industries11/18/2025
Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.
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Tablets And Capsules: Overcoming Similar Obstacles In Production7/30/2024
Explore how understanding specific USP chapters can address common tablet and capsule production challenges and ensure high-quality results in this essential pharmaceutical process.
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NanoImprove The Performance Of Your Formulations9/24/2024
Learn how Nanoforming can help improve the performance of your molecule by increasing drug loads, improving bioavailability, enhancing drug delivery profiles, and supporting product differentiation.
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Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives7/17/2024
A gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.
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A Powerful Non-Destructive Tool For Tablet Characterization10/6/2025
Discover how X-ray micro-CT provides vital, non-destructive analysis of a tablet’s internal 3D physical structure. This structural insight is essential for troubleshooting defects and confirming performance.
SOLID DOSE MANUFACTURING SOLUTIONS
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With many of the blockbuster biologic drugs of the ’90s are coming off of patent, companies are racing to provide a clinically similar alternative to these pioneering products. Like any biologic drug, they require care and attentiveness throughout the manufacturing process. Therefore, it is necessary to maintain aseptic conditions throughout the production process of these drug products.
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Dec provide custom designed isolators for dispensing and/or sampling from various containers such as bags and drums into intermediate packagings or for direct charging into process equipment. These systems offer high containment and a controlled environment offering fast cleaning and drying features allowing for swift product changes.
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If you handle multiple packaging, Dec can help in providing one single multi-packaging filling station handling FIBCs, drums, cardboard boxes etc.).
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Oral solid dose manufacturing supports complex formulations with flexible scales, specialized technologies, and integrated packaging for reliable clinical and commercial supply.
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Natoli’s line of affordable tablet presses is designed, engineered, and manufactured in the U.S.A. and built on our decades of experience in the tableting industry. We know our customers want presses that efficiently meet their R&D and/or production needs.
With Natoli you have a choice in your tablet press: R&D or production, single-station or rotary, fully automated or manual. Whatever your need, Natoli’s best-in-class tablet presses can help you optimize tablet quality while saving time and reducing costs.