INSIGHTS ON SOLID DOSE MANUFACTURING
-
Die Bore Cracking: How To Achieve Reliable Tablet Production
Die bore cracking is a significant issue in tablet manufacturing, affecting the quality of the tablets and potentially damaging the tablet press. Explore how to analyze for and prevent this damage.
-
Innovations, Solutions, And USP <1062> With Scale Up
Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
-
Segments: Next-Generation Tablet Press Technology
Segments increase press output by up to 25% and cut setup time by 88%. Learn the benefits, drawbacks, and manufacturing needs of this rapidly growing tablet press technology.
-
Technology To Overcome Absorption Hurdles And Solubility Limitations
For poorly soluble drugs, overcoming absorption hurdles can hinder development. Explore a solution that empowers researchers to overcome solubility limitations and accelerate drug development.
-
Bridging The Gap Between Product Readiness And Equipment Availability12/15/2025
Discover how manual precision at scale bridges packaging gaps, accelerates product launches, and ensures uninterrupted supply to deliver quality when automated equipment isn’t yet operational.
-
Future-Proofing Aseptic Manufacturing3/27/2025
Investing in adaptable aseptic manufacturing pays off. Find out how flexible systems, despite higher initial costs, handle complex drugs and changing volumes to boost productivity and quality.
-
How To Avoid Sticking And Picking In The Tableting Industry9/23/2024
Review strategies to mitigate sticking and picking risks in the tablet industry, and learn how you can foster improved tablet production processes, ensuring higher quality and consistency.
-
Understanding Aseptic Powder Filling: Key Principles And Techniques3/27/2025
Pharmaceutical production of sterile powders presents unique hurdles. Explore the core principles and advanced techniques vital for aseptic filling, from containment to precise dosage control.
-
Blister Solutions3/4/2025
With over 6,000 tooling parts and an in-house machining center to ensure precision, explore this versatile blister service that provides both Thermoformed and Cold-Formed solutions.
SOLID DOSE MANUFACTURING SOLUTIONS
-
Used Powrex high shear mixer, model FM-VG-25, stainless steel construction, 15 liter working capacity with high speed chopper driven by 1.5 kw motor, main shaft driven by 3.7 kw motor, with controls, serial# 903222, built 1990.
-
Used Filamatic Filler, Model AB-5, with fill piston and filling nozzle, 110 volt, serial# 022578.
-
Natoli Engineering Company, through its Carlisle Precision Encapsulation Parts subsidiary, manufactures premium change and spare parts for many brands of encapsulation machines.
-
Used Sejong Encapsulator, with change parts/tooling, 600 volts, 3 phase.
-
Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.