INSIGHTS ON SOLID DOSE MANUFACTURING
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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A Powerful Non-Destructive Tool For Tablet Characterization
Discover how X-ray micro-CT provides vital, non-destructive analysis of a tablet’s internal 3D physical structure. This structural insight is essential for troubleshooting defects and confirming performance.
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Paediatric Drug Product Development Through To Commercialisation
Learn how an innovative pediatric minitablet achieved patient-friendly administration, precise dosing and scalable manufacturing to support a smooth path to market.
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5 Hidden Risks In Early-Phase OSD Formulation Development
Early formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.
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Patient Adherence With A Novel Dosage Form11/13/2025
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Rational Design And Material-sparing Strategies For Enabled Intermediates And Drug Products9/9/2026
A material-sparing strategy integrating formulation mapping, lab-scale spray drying, and compact screening can accelerate risk identification and inform first-round tablet formulation decisions for poorly soluble APIs.
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Zhunan Facility Site VR Tour12/23/2025
Bora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
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Ask Us Anything: Hannah McLachlan on Crystallization In Peptide Development7/24/2026
Hannah McLachlan, Project Scientist IV at Cambrex Edinburgh, on what crystallization screening delivers for peptide therapeutics — more stable material, higher purity, and a molecule clients can store without specialist infrastructure.
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Solubility Enhancement Via Amorphous Solid Dispersions2/27/2025
Polyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
SOLID DOSE MANUFACTURING SOLUTIONS
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AIM™ Pro Plus Control System Makes Tablet Production Easy
The Natoli AIM™ Pro Plus control system is a flexible software and hardware architecture that is standard on Natoli production tablet presses. This industry-leading package can be retrofitted to almost any production tablet press to increase production, improve tablet consistency, and provide an easier-to-manage production environment. -
ROSS Dual Shaft Mixers are durable, versatile systems designed for precise processing of high-performance formulations across diverse rheologies, solids loading, temperatures, and pressures.
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Learn how closed systems, advanced facilities, and flexible batch strategies support safe development and reliable commercial supply.
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Natoli Scientific is dedicated to developing high-quality affordable products for your market needs.
We provide a formulation design based on a strong scientific understanding and decoding interplay of materials and process parameters to ensure product integrity. We use traditional as well as principles of ‘Quality by Design (QbD)’ to develop robust lead prototype formulations. The early sound scientific investment in product development saves time and money during scale-up and commercial manufacturing.
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Paediatric drug development demands careful attention to dosing, taste, stability, dosage form design, and regulatory requirements to ensure safe, effective therapies.