INSIGHTS ON SOLID DOSE MANUFACTURING
-
HPAPI Containment: A Full Lifecycle Safety Innovation
Containing highly potent APIs across a full operational lifecycle requires a structured approach that addresses hazard scoring, quality by design, performance testing, and safe enclosure disposal.
-
Powder Rheology: Gateway For Tablet Sticking Insights
Powder rheology offers a scientific method to predict and mitigate tablet sticking issues, helping to ensure smoother pharmaceutical production cycles through early material and tooling selection.
-
When To Consider Material And Personnel Airlocks For Downflow Booths
Strategic use of airlocks in downflow booth design enhances pressure stability and containment. A risk-based approach ensures facility integration meets rigorous safety and compliance standards.
-
Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months
A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
-
Bridging The Gap Between Product Readiness And Equipment Availability12/15/2025
Discover how manual precision at scale bridges packaging gaps, accelerates product launches, and ensures uninterrupted supply to deliver quality when automated equipment isn’t yet operational.
-
Zhunan Facility Site VR Tour12/23/2025
Bora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
-
Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery1/27/2025
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
-
Combining Patient Centricity And Commercial Viability In Pediatric Product Development8/15/2024
Medication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.
-
Contract Pharma 2026: Mikart On CDMO Collaboration4/30/2026
An overview of a milestone pharmaceutical outsourcing conference focused on CDMO collaboration, tech transfer, and oral solid and liquid dose manufacturing strategies.
SOLID DOSE MANUFACTURING SOLUTIONS
-
Natoli Engineering now offers AIM™ Data Acquisition & Analytical Software for the Natoli NP-RD10A research and development tablet press. The combination of AIM™ Software and this R&D tablet press enables the researcher to evaluate formulation properties and identify potential tableting issues—including capping, lamination, sticking/picking, and tablet robustness—during the tablet development process. Plus, the software can optimize tablet tensile strength and lubrication for successful large-scale manufacturing production.
-
Used Korsch rotary tablet press, model PH106-DMS, 6 station, 40 KN compression pressure, keyed upper punch guides, 15 mm max tablet diameter, 15 mm max depth of fill, force feeder with feed hopper, rated up to 32,400 tablets/hour, with control panel, machine# 1.0062.95.
-
Used 60" O'Hara FastCoat coating pan, model FC400 (60xc5), stainless steel construction with 60" diameter perforated Pan, solvent rated design, O'Hara advanced controls with Allen Bradley Compact Logix PLC, PC and HMI units, O'Hara manifold with Schlick nozzle spray arm, built in Watson Marlow peristaltic pump with Micromotion mass flow and recirculation system, reverse pan unloading, outdoor rated air handling unit (AHU) with preheat steam coil, chilled water dehumidification unit, steam reheat with face/bypass temp control dampers, HEPA module, Camfil DCU with FIKE suppression and isolation system, bag in bag out with exhaust HEPF module, 480 volt, system serial# 4501, built 2020.
-
Maintain peak safety and sterility in sensitive environments with advanced isolation technology. Ensure strict compliance and reliable protection during critical, high-stakes processing tasks.
-
Used 79 gallon (300 liter) Inox reactor, stainless steel construction, approximately 24" diameter x 34" straight side, dish lid top with dish bottom, jacket and interior rated 30 psi and full vacuum at 300 F, 6" top access, with (1) 4", (1) 3", (2) 2" and (2) 1.5" nozzles on top, with bottom entering magnetic agitator, .75 hp with controls, 1.5" center bottom outlet, with load cells, all on portable frame, serial# 95011-2, CRN# K82555, built 1995.