INSIGHTS ON SOLID DOSE MANUFACTURING
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HPAPIS Production: "Where Micrograms Matters"
In HPAPI manufacturing, micrograms make a difference. Risk‑based containment, smart facility design, and exposure limits safeguard people, product, and performance.
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Engineering Challenges Of Designing Pharmaceutical Isolators
Designing pharmaceutical isolators requires navigating complex engineering hurdles, from ensuring chemical compatibility to optimizing airflow and pressure. Explore the critical considerations that guarantee drug manufacturing safety and efficiency.
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Achieving Licensing For A Healthcare Solution
Facing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.
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Maximizing Product Potential With Spray Drying
Discover how spray drying can help optimize solubility, stability, and particle engineering for more efficient pharmaceutical development.
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Overview Of Hot Melt Extrusion And Its Pharmaceutical Applications8/31/2026
More than 40% of NCEs face aqueous solubility challenges. Here, we examine how hot melt extrusion addresses solubility, modified release, abuse deterrence, and scale-up across pharmaceutical development.
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Compaction Simulation For Tablet Technology Transfer And Scale-Up7/15/2026
Compaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.
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Don't Let Your Filling Equipment Dictate Your Drug Formulation6/1/2026
Gravimetric powder dosing measures true mass to eliminate equipment-driven reformulation, preserving particle design and speeding clinical development.
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Optimising Solubility: Selecting The Right Technology For Early Drug Development5/6/2026
Discover how selecting the right solubility‑enhancing technology improves early exposure, supports flexible dosing, and lays a strong foundation for downstream oral drug development.
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Ask Us Anything: Daniele Vigo On Cost-Effective Process Development7/23/2026
Daniele Vigo, Assistant Director at Cambrex Milan, on getting yield, purity, and scalability right without burning through the budget.
SOLID DOSE MANUFACTURING SOLUTIONS
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Natoli Scientific takes pride in its comprehensive USP<1062> Tablet Compression Characterization services, tailored to address the complexities of tableting in pharmaceutical manufacturing. Staying true to the parameters outlined in the United States Pharmacopeia (USP) Chapter 1062, our approach meticulously evaluates tablet compression behaviors. By thoroughly characterizing the compression profile, we can pinpoint the optimal compression force required to form a cohesive tablet without applying undue stress that could lead to capping — the separation of tablet tops during or after the compression phase.
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Used IMA Zanasi 6 F Capsule Filler, rated up to 6000 capsules/hour, no change parts, capable of producing 00-5 size capsules, with controls and Siemens PLC, 230 volt, 3 phase, serial# 35071, built 2006.
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One (1) used Vectro granulator, mdoel CF360EX, stainless steel construction, 3-5 kg capacity, xp design with controls, 220 volt, serial# CF-110, new 1982.
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Eurofins CDMO Alphora handles small molecule APIs and HPAPIs from IND-enabling through commercialization, with FDA and Health Canada-approved facilities scaling up to 125 kg per batch. Contact them to discuss your program.
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Standard and customized 2D and 3D fluid containment systems. With a wealth of experience, knowledge, and solid quality processes behind every Thermo Scientific™ product, we will help you feel assured that your bioproduction process performs at its best.