INSIGHTS ON SOLID DOSE MANUFACTURING
-
![GettyImages-1140632275-tablet-bottle-manufacturing]( "Advancements In Tablet Compression Tooling: What Manufacturers Need To Know")
Advancements In Tablet Compression Tooling: What Manufacturers Need To KnowDiscover how continuous manufacturing, AI-driven digital twins, and advanced tooling materials are transforming tablet compression to boost quality and cut operational costs in pharmaceutical production.
-
![cdmo-solid-dose-GettyImages-1432665138]( "The Importance Of Polymorph Screenings")
The Importance Of Polymorph ScreeningsDiscover how systematic polymorph screening reduces development risk, safeguards product performance, and enables confident solid‑form selection across the drug development lifecycle.
-
![Dalton photo 2]( "How To Handle Intrinsic Product Powder Particles")
How To Handle Intrinsic Product Powder ParticlesPowder filling creates intrinsic particles that interfere with continuous monitoring. Risk‑based strategies must separate product dust from true contamination to meet Annex 1 requirements.
-
![cdmo-solid-dose-GettyImages-1432665138]( "Safely Scaling High Potency API Manufacturing")
Safely Scaling High Potency API ManufacturingScaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scale‑up.
-
The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
-
Low-Bioburden Powders For Terminal Sterilisation2/24/2026
Low‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
-
How To Avoid Sticking And Picking In The Tableting Industry9/23/2024
Review strategies to mitigate sticking and picking risks in the tablet industry, and learn how you can foster improved tablet production processes, ensuring higher quality and consistency.
-
Isolators For Pharmacy Compounding – Time For Change?3/14/2025
Maintaining a contamination-free environment is crucial in drug compounding. Learn how isolator systems can improve safety, efficiency, and regulatory compliance.
-
Developing And Manufacturing Minitablets To Extend Drug Lifecycle1/27/2025
Pharmaceutical companies should leverage oral minitablets to extend drug lifecycles, optimize dosing, and improve patient-centric solutions while overcoming manufacturing challenges.
SOLID DOSE MANUFACTURING SOLUTIONS
-
![GettyImages-669121480-pill-tablet-capsule-OSD-oral-solid]( "Compaction Simulation / Emulation")
Building on the capabilities of the NP-RD10A benchtop tablet press (discussed in our previous article on USP <1062>), our services are further enhanced by the integration of the Presster™ compaction emulator. This state-of-the-art tool is designed to replicate the compaction dynamics of production tablet presses in a laboratory setting. It allows for tangible fine-tuning of the compression cycle, providing an accurate depiction of how a tablting formulation will behave under commercial manufacturing conditions. Using the Presster, Natoli Scientific can simulate full-scale production, permitting us to forecast problems before they escalate to costly production delays. Our experts can optimize the tablet design for our clients, ensuring a smooth transition from laboratory to production while adhering to the rigorous standards set by the industry including the current USP <1062> chapter.
-
![60 OHara FastCoat Coating Pan]( "Used O'Hara Pharmaceutical Tablet Coating Pan: FC400")
Used 60" O'Hara FastCoat coating pan, model FC400 (60xc5), stainless steel construction with 60" diameter perforated Pan, solvent rated design, O'Hara advanced controls with Allen Bradley Compact Logix PLC, PC and HMI units, O'Hara manifold with Schlick nozzle spray arm, built in Watson Marlow peristaltic pump with Micromotion mass flow and recirculation system, reverse pan unloading, outdoor rated air handling unit (AHU) with preheat steam coil, chilled water dehumidification unit, steam reheat with face/bypass temp control dampers, HEPA module, Camfil DCU with FIKE suppression and isolation system, bag in bag out with exhaust HEPF module, 480 volt, system serial# 4501, built 2020.
-
![ACG Pam Mini FIlled Capsule Sorter]( "Used ACG Pam Capsule Sorter")
Used ACG Pam Mini Filled Capsule Sorter, model MCS100, stainless steel construction, 9" x 12" sorting area, serial# MCS-559.
-
![Natoli - FastLock_450x300]( "FastLok Die Table Surface")
Revolutionize your tablet press with the FastLok™ Die Table Surface from Natoli Engineering. Our exclusive and patented snap-in technology makes changeovers fast, easy, tool-less — getting your press back to full production in minutes.
-
![Pharmaceutical Tablet Press]( "Pharmaceutical Tablet Press")
Natoli’s line of efficient tablet presses combine remarkable tablet production, automation and dependability.
