INSIGHTS ON SOLID DOSE MANUFACTURING
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Die Bore Cracking: How To Achieve Reliable Tablet Production
Die bore cracking is a significant issue in tablet manufacturing, affecting the quality of the tablets and potentially damaging the tablet press. Explore how to analyze for and prevent this damage.
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Improving API Solubility Using Hot Melt Extrusion Formulation
Solubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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M6 Tablet Metal Detector For Pharmaceutical And Nutraceutical Production
Ensure the safety and quality of your tablets and capsules with a metal detector designed for stability and high sensitivity in pharmaceutical and nutraceutical production.
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Round Tablet Compression Tooling — To Key Or Not To Key The Punches
What makes the keying in tablet compression tooling, specifically in tablet punches, so important to the tablet manufacturing processes?
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Taste-Masked Dosage Forms For Pediatric Oral Delivery: An Industrial Perspective7/18/2024
Leveraging strategies and technologies for pediatric patient compliance for taste masking and controlled release in pharmaceutical products, enables flexibility in dosage and format options.
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Lower Punch Tip Bending / Buckling11/11/2024
When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.
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Seizing Market Share Pre-Patent Expiry: The Evolution Of A CDMO Partnership In Navigating A Paragraph IV ANDA Submission6/26/2024
The dynamic pharmaceutical landscape demands agility and strategic foresight. Explore how leveraging a key partnership helped to overcome a looming patent expiry for a second-generation acne medication.
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How To Solve Complex Pediatric Dosing Challenges Using Tailored Solutions8/11/2025
With a partner who understands the science, the regulations, and the real-world demands of dosing children, development can move faster, smarter, and with greater confidence
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Combining Patient Centricity And Commercial Viability In Pediatric Product Development8/15/2024
Medication acceptance and adherence are critical concerns in pediatric populations due to these patients’ rapid anatomical and physiological development.
SOLID DOSE MANUFACTURING SOLUTIONS
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Used Korsch rotary tablet press, model PH106-DMS, 6 station, 40 KN compression pressure, keyed upper punch guides, 15 mm max tablet diameter, 15 mm max depth of fill, force feeder with feed hopper, rated up to 32,400 tablets/hour, with control panel, machine# 1.0062.95.
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When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
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Ensure the safety of your personnel, products, and patients with contamination control solutions. From compounding isolators to cleaning and disinfection, discover comprehensive solutions for your pharmacy.
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Inno4Life, part of the Dec Group, has in-depth knowledge and containment equipment solutions for the aseptic/sterile Fill-Finish pharmaceutical industry. In line with ISO 14644, including monitoring of viable and non-viable monitoring to comply with the most recent revisions of the ISPE containment specifications cGMP and GAMP5 guidelines.
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The NP-RD10A fits on benchtop areas and is constructed with an electro-less nickel frame. Using this tablet press in lab research significantly helps to improve tablet uniformity, reduce trial-and-error, decrease formulation waste, and save valuable time and effort.