INSIGHTS ON SOLID DOSE MANUFACTURING
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Closing The Duration Gap In FDA-Approved Long-Acting Contraceptives
A gap exists between three months and three years in FDA-approved long-acting contraceptives (LACs). A microsphere formulation enables sustained release over a six to twelve-month period.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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Bridging The Gap Between Product Readiness And Equipment Availability
Discover how manual precision at scale bridges packaging gaps, accelerates product launches, and ensures uninterrupted supply to deliver quality when automated equipment isn’t yet operational.
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Developing And Manufacturing Minitablets To Extend Drug Lifecycle
Pharmaceutical companies should leverage oral minitablets to extend drug lifecycles, optimize dosing, and improve patient-centric solutions while overcoming manufacturing challenges.
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Lower Punch Tip Bending / Buckling11/11/2024
When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.
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Innovative ASD Technology Improves Abandoned Cancer Medication3/1/2024
Review this case to learn how one solid dispersion technology lowered patients' pill burdens and demonstrated an improved therapeutic response for Galeterone.
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Softgel Formulation: Addressing Stability, Shelf-Life, And Bioavailability5/16/2024
A CDMO that has expertise and resources in softgel formulation can help companies address stability issues, improve drug bioavailability, or ensure compliance with regulations.
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Achieving Manufacturing Efficiency In OSD Manufacturing10/16/2024
Gain expert insight into the importance of instrumented tablet presses in assessing formulation properties, the role of tablet cup configurations, and scalability parameters for successful product transfer.
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The Future Of Oral Solid Dose Development And Innovation2/27/2025
Tom Sellig, CEO of Adare, discusses the ongoing relevance of small molecules, oral solid dose development, trends like GLP-1, and innovations like 3D printing in pharmaceuticals.
SOLID DOSE MANUFACTURING SOLUTIONS
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Part of our Evolve range, this RTU-based, automated fill-finish platform can fill liquids and powders on the same line. Ideal for dual chamber formats and reconstitution devices.
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Send a test sample of your powder to Natoli Scientific to get your formula characterized following USP <1062> Guidelines (Tablet Characterization Methods) that we have been practicing for over 25 years.
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Used Kikusui tablet in tablet press, model Aquarius G-J/DC, 36 station, keyed upper punch guides, B tooled, 100 kN pre-compression, 100 kN main compression, 16mm max tablet diameter, 18mm max depth of fill, rated up to 259,200 tablets/hour, with DC module for core feeder, 4-15mm core depth adjustment, with integrated primary and secondary powder feed hoppers, and core feed hopper, project# 1-6302, built 2009.
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Used Elizabeth Hata R&D tablet press, model EP200, B/D tooled with 10 station turret, 5 stations each B and D, 16 mm B, 22 mm D max tablet diameter, 17 mm B, 18 mm D max depth of fill, rated up to 6000 tablets/hour, with feed hoppers and feed frames, Machine #81, built 2011.
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Used GlobePharma Single Station Tablet Press.