INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-1276633131 digital twins]( "Harnessing Digital Twins To Optimize Tablet Manufacturing")
Harnessing Digital Twins To Optimize Tablet ManufacturingUnlock manufacturing precision with digital twins. Learn how virtual replicas of production systems enable predictive maintenance, streamline scale-up, and ensure consistent product quality in pharma.
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![Natoli - tool and tablet]( "Tablet Consistency And Punch Length – A Pragmatic Perspective For European Manufacturers")
Tablet Consistency And Punch Length – A Pragmatic Perspective For European ManufacturersTablet consistency relies on a balance of formulation, press mechanics, and tooling. Learn why punch length tolerance is often overstated and what other critical factors truly drive quality and uniformity.
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![GettyImages-1208573753-scientist-fizz-solubility-lab-glass]( "Improving API Solubility Using Hot Melt Extrusion Formulation")
Improving API Solubility Using Hot Melt Extrusion FormulationSolubility of active pharmaceutical ingredients (APIs) is a challenge in drug development. Discover how hot melt extrusion with polyvinyl alcohol enhances API solubility and stability to offer improved drug delivery.
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![Picture2]( "How To Fast-Track Your Oral Solid Dose To Phase 1")
How To Fast-Track Your Oral Solid Dose To Phase 1A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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How Solid-State Characterization Shapes Drug Development7/23/2026
Mark Benger, Site Director at Cambrex Edinburgh, on solid-state characterization as an insurance policy — front-loaded work that quietly determines whether a program survives the jump from kilos to tonnes.
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Advancements In Tablet Compression Tooling: What Manufacturers Need To Know10/30/2025
Discover how continuous manufacturing, AI-driven digital twins, and advanced tooling materials are transforming tablet compression to boost quality and cut operational costs in pharmaceutical production.
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Zhunan Facility Site VR Tour12/23/2025
Bora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
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Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability7/15/2026
Molecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.
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Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery1/27/2025
Delve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
SOLID DOSE MANUFACTURING SOLUTIONS
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![AST innovation]( "A User-Friendly Solution For Fill-Finish Professionals")
When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.
Does an isolator need to be ergonomically unfriendly to clean?
Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).
Does routine maintenance have to be time-consuming and laborious?
Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?
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![medprocesses_granulator_3_1.jpg]( "Containment: Granulator Technology")
Used for lab scale and production operations at multiple International Pharma manufacturers, our Granulator containment technology applications take the idea of retrofits to another level.
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![Dec 1]( "Loading And Charging Of Drums For High Potent API's: IsoTube")
Isotube is an effective option for the safe loading and charging of multiple drums of HPAPIs. Compared to the DCS® Drum Containment System for safely discharging drums, it is the preferred choice when charging lumpy and agglomerated products as a lump breaker system can be included in the lower part of the discharge hopper.
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![Aseptic Filling Systems For High Containment Applications]( "Aseptic Filling Systems For High Containment Applications")
Dec offers filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.
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![Natoli]( "Control Software For Production Tablet Presses: AIM™ Pro Plus")
AIM™ Pro Plus Control System Makes Tablet Production Easy
The Natoli AIM™ Pro Plus control system is a flexible software and hardware architecture that is standard on Natoli production tablet presses. This industry-leading package can be retrofitted to almost any production tablet press to increase production, improve tablet consistency, and provide an easier-to-manage production environment.
