INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-1276633131 digital twins]( "Harnessing Digital Twins To Optimize Tablet Manufacturing")
Harnessing Digital Twins To Optimize Tablet ManufacturingUnlock manufacturing precision with digital twins. Learn how virtual replicas of production systems enable predictive maintenance, streamline scale-up, and ensure consistent product quality in pharma.
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![GettyImages-2158862132-vials-robotic-arm-filling-liquid-handling-lab]( "Liquid Suspension Trends In The CDMO Space")
Liquid Suspension Trends In The CDMO SpaceLiquid suspension formulations are rapidly growing in pharma, driven by patient needs, formulation advances, and CDMO innovation.
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![3P innovation - achieving licensing]( "Achieving Licensing For A Healthcare Solution")
Achieving Licensing For A Healthcare SolutionFacing strict regulations and tricky powders, a healthcare client sought an advanced filling solution. Learn how an expert collaboration led to licensed product, boosting precision and productivity.
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![Scientist-with-tablet-GettyImages-950594528]( "Functional Release Multiparticulates Slam")
Functional Release Multiparticulates SlamReview Adare Pharma Solutions’ innovative technologies and learn how these capabilities can improve patient outcomes and improve manufacturing efficiency.
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Head Pressure In Your Hopper: What Is It, And How Do You Mitigate It?7/30/2024
What is head pressure in your hopper and how does it relate to tablet press performance?
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Developing And Manufacturing Minitablets To Extend Drug Lifecycle1/27/2025
Pharmaceutical companies should leverage oral minitablets to extend drug lifecycles, optimize dosing, and improve patient-centric solutions while overcoming manufacturing challenges.
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Orally-Disintegrating Dosage Forms With Taste Masked Multiparticulates7/17/2024
Learn more about our orally disintegrating tablet (ODT) capabilities and how these innovative technologies have the potential to improve acceptance, adherence, and compliance in pharmacotherapy.
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Zhunan Facility Site VR Tour12/23/2025
Bora’s 36,000-square-meter Zhunan, Taiwan facility delivers flexible, high-quality cGMP oral solid dose manufacturing with access to major markets including North America and the EU.
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Advancements In Tablet Compression Tooling: What Manufacturers Need To Know10/30/2025
Discover how continuous manufacturing, AI-driven digital twins, and advanced tooling materials are transforming tablet compression to boost quality and cut operational costs in pharmaceutical production.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Natoli - turret_450x300]( "Replace Your Worn Segmented Turret Today")
Now you can upgrade to Natoli’s premium segmented turret for your Fette Press! Natoli Engineering has 20 years’ experience in manufacturing segments, backed by ongoing investments in advanced R&D, CNC process automation, and precision finishing which meets often surpasses the OEM - Our quality is in the detail. The Fette patent is now expired, and Natoli is ready to deliver unmatched quality and performance.
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![Pharma containment isolators]( "Pharmaceutical Containment Isolators")
Our Rigid Stainless Steel Containment Isolators have been designed for handling potent compounds that can offer guaranteed levels of operator protection as low as 10ng/m3 (task duration). These include designs for sampling, dispensing and sub-division, mixing, milling and vessel charging, as well as containing integrated process devices such as filter dryer units, tablet press enclosures, blenders, mills and pack off systems.
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![Pharma-Drum]( "Pharmaceutical Drum Containment Systems")
The patented DCS® pharmaceutical Drum Containment System is a stainless steel cylindrical glove box with a glass cover and two glove ports. Highly economical in comparison with conventional isolation systems, DCS® ensures precise, contamination free emptying of drums providing high containment (< 1 µg/m3).
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![Stokes Tablet Press]( "Used Stokes 45 Station Pharmaceutical Tablet Press")
Used Stokes BB2 Tablet Press, 45 station, B-tooled, dual sided, 4 ton compression, feed frames with hoppers, 7/16" max tablet diameter, 11/16" max depth of fill, 4200 tablets per minute max speed.
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![iStock-870087778-powder]( "Powder Flow Properties & Characterization Services")
Basic Powder Flow Characterization [USP <1174>]:
A powder flow analysis is an indicator of how well formulation will release from the hopper during the tableting. It is important to know that the developed formulation is showing ‘Mass Flow’ or ‘Funnel Flow’ or ‘Rat Holing’.
Powder blend shows ‘Mass Flow’ when the entire solid bed is in motion during the discharge of material from the outlet. This is a ‘First-in-First-Out’ process. Hoppers offering ‘Mass Flow’ have steep and/or low-friction walls. This flow offers ‘No-Arching’, ‘Less Segregation’, and ‘Stable Powder Flow’.
When the hopper is not sufficiently steep and smooth enough to ensure sliding along its wall, the powder blend exhibit ‘Funnel Flow’. Such hoppers are sensitive to arching and ratholing. In this case, powder discharge from the hopper is not predictable.
