INSIGHTS ON SOLID DOSE MANUFACTURING

SOLID DOSE MANUFACTURING SOLUTIONS

  • When AST came to the table on the design for our new fill-finish isolator, one of the first areas AST engineers wanted to address was the usability and accessibility of the isolator and corresponding operations. With our customers’ point of view in mind, we wanted to address specific points of friction routinely encountered by operators and closely examine whether those friction points were necessary.

    Does an isolator need to be ergonomically unfriendly to clean?

    Should simple mechanisms like isolator doors be challenging to engage? (As much as one can appreciate exercise, no one wants to do “arm day” in cleanroom coveralls).

    Does routine maintenance have to be time-consuming and laborious?

    Many of these factors are accepted as par for the course in aseptic fill-finish manufacturing. Our question was, why?

  • Used Shionogi Qualicaps capsule checkweigher, model CWI-40, nominally rated up to 40000 capsules/hour throughput, with weigh check option, capsule reject system, stainless steel feed hopper, includes size 00, 0, 1, 2, 3, and 4 change parts with HMI touchscreen, serial# S0053, built 2004.

  • The semi-automated capsule filler is part of the Explore Range, offering the potential to simplify formulation by eliminating the need for additional ‘formulation for powder filling’ steps.

  • Dec excels in providing comprehensive technical solutions for packing powders into bags and drums from process equipment discharge such as a dryer or a mixer, milling and dispensing to the final packing of the product.

  • Dec provide custom designed isolators for dispensing and/or sampling from various containers such as bags and drums into intermediate packagings or for direct charging into process equipment. These systems offer high containment and a controlled environment offering fast cleaning and drying features allowing for swift product changes.