INSIGHTS ON SOLID DOSE MANUFACTURING

• Advancing High Potency Manufacturing

  Advance potent drug manufacturing through tighter containment, thoughtful process engineering, and closed handling that protects workers while improving efficiency and scale.

• A Simple And Powerful Solution For Accelerating Dissolution

  Many poorly soluble drugs fail not because of low solubility, but because they dissolve too slowly. Learn how focusing on dissolution rate can unlock absorption gains using simple strategies.

• Practical Formulation Strategies For Poorly Soluble APIs

  Poor aqueous solubility now defines most drug candidates in development, making early screening and solid-state assessment essential to achieving reliable exposure and avoiding costly reformulation downstream.

• Lower Punch Tip Bending / Buckling

  When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.

• How To Achieve Late-Phase Success In Complex OSD Development

  8/31/2026

  Late-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.

• Global Regulatory Harmonization: Comparisons In Aseptic Barrier Systems

  4/20/2026

  Compare global aseptic standards from the FDA, EMA, PIC/S, and WHO. Gain insights into how advanced barrier systems harmonize international requirements to ensure sterile product integrity and safety.

• Direct API Capsule Filling: A Faster Path To Market

  9/16/2026

  Direct API capsule filling eliminates complex formulation steps, leveraging volumetric drum dosing and 100% net weight verification to accelerate drug development timeline efficiency.

• Compaction Simulation For Tablet Technology Transfer And Scale-Up

  7/15/2026

  Compaction simulation de-risked tech transfer for a 40 mg fexuprazan tablet by defining optimal roller compaction and lubrication parameters before scale-up. Access the full case study to see the data.

• Benefits Of Single-Use Isolators For Cytotoxic Payload Handling

  6/15/2026

  Managing cytotoxic ADC payloads in shared containment facilities creates mounting compliance, safety, and operational costs that single-use isolator technology is designed to address.