INSIGHTS ON SOLID DOSE MANUFACTURING
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How To Fast-Track Your Oral Solid Dose To Phase 1
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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A Simple And Powerful Solution For Accelerating Dissolution
Many poorly soluble drugs fail not because of low solubility, but because they dissolve too slowly. Learn how focusing on dissolution rate can unlock absorption gains using simple strategies.
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Shaping The Future Of Solid Dose Manufacturing With Hot Melt Extrusion
Enhance your drug development strategies today and master hot melt extrusion by learning about excipient selection, equipment setup, novel screening tools, and process optimization.
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Lower Punch Tip Bending / Buckling
When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.
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FastLok™ Die Table Surface Overview10/8/2025
Learn about a toolless, removable surface that allows for rapid, on-turret plate replacement in minutes, not weeks, significantly improving operational efficiency.
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Achieving Manufacturing Efficiency In OSD Manufacturing10/16/2024
Gain expert insight into the importance of instrumented tablet presses in assessing formulation properties, the role of tablet cup configurations, and scalability parameters for successful product transfer.
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Predicting Food Effects In Oral Drug Delivery Using PBPK Modeling7/15/2026
Learn how integrated PBPK and molecular dynamics modeling predicted an ~11% fed-state Cmax increase for fenofibrate, giving formulation teams earlier, mechanistic insight into food-dependent absorption.
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Benefits Of Isolator Technology In Fill-Finish12/10/2025
Isolator technology enhances sterility assurance, reduces contamination risk, improves operator safety, and supports regulatory compliance, making it essential for modern aseptic fill-finish operations.
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Advances In Oral GLP-1 Analogs For Obesity9/12/2024
Discover how these groundbreaking Oral GLP-1 Analogs therapies are reshaping obesity management and addressing key challenges in formulation and delivery.
SOLID DOSE MANUFACTURING SOLUTIONS
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At Natoli, we know that quality is paramount. Our cutting‐edge Precision CT Scan Service is designed to detect even the subtlest imperfections in tablets, ensuring you achieve the highest standards of quality every time.
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IMA Precisa 18 High Speed Tablet/Capsule Checkweigher, serial# PA1114.
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Hata Tablet Press, Model HT-AP55-DU/I.E. Double sided, serial number Nov. 90 - Oct. 1991
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PTS Powder Transfer System® challenges convention by using both vacuum and pressure to move powders as if they were liquids. This eliminates the need for gravity charging and therefore making multi floor processes a requirement of the past.
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Ensure operator safety and product purity with unidirectional airflow solutions. Explore how modular ISO 5 environments provide containment and cross-contamination control for critical processes.