INSIGHTS ON SOLID DOSE MANUFACTURING
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Safely Scaling High Potency API Manufacturing
Scaling HPAPI production demands disciplined containment and exposure control. Integrated operating models help manage risk while enabling compliant, reliable scaleāup.
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The Importance Of Tablet Density Uniformity
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
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How To Fast-Track Your Oral Solid Dose To Phase 1
A strategic approach accelerates oral solid dose development by uniting molecular analysis, solubility improvement, formulation design, manufacturing efficiency, and stability testing to reach Phase 1 faster.
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Breaking The GLP-1 Manufacturing Bottleneck: Single Use For Safer Scale Up
Streamline GLP-1 scale-up by replacing heavy container cleaning with single-use powder handling to boost containment and manufacturing capacity.
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Solubility And Improved Patient Outcomes9/9/2026
Poor solubility poses major development challenges. Innovative formulation technologies and careful excipient selection can improve bioavailability and product performance.
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Raise Your Standards With Downflow Booth Airflow Containment1/30/2026
Ensure personnel safety during hazardous material handling by mastering airflow dynamics and containment screens. Learn to achieve low exposure levels through advanced HEPA filtration methods.
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GLP-1 OSD Chemical Synthesis Workflow6/29/2026
Enhance containment and process reliability in oral GLP-1 synthesis. Discover how integrated single-use assemblies and automated fluidics safeguard chemical purity during scale-up.
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Small-Scale Automatic Micro-Dosing Of Powders Into Blisters9/2/2026
Optimize inline X-ray fill weight verification with precise blister calibration, automated HMI calibration file creation, and 2D code tracking.
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Maximizing Product Potential With Spray Drying9/23/2026
Discover how spray drying can help optimize solubility, stability, and particle engineering for more efficient pharmaceutical development.
SOLID DOSE MANUFACTURING SOLUTIONS
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Explore a wide variety of DHR temperature systems and accessories, designed for superior performance and ease-of-use.
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Used Key International single station bench top tablet press, model: SC-2. 1.5 ton compression pressure, approximately .5" max tablet diameter, .5625" max depth of fill, manual operation, serial# JI4786.
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Partner with Natoli Scientific during the earliest stages. Our scientific expertise with state-of-the-art analytical capabilities is ready to take any preformulation challenge.
Natoli scientific has an expertise of handling a wide range of APIs for the development of oral solids. We apply principles of ‘Quality by Design’ to define Critical Material Attributes (CMA), Critical Process Parameters (CPP), Critical Quality Attributes (CQA) and Quality Target Product Profiles (QTPP). Because we believe that understanding material and process as much as possible in the early life cycle of drug product development program is an insurance for further development path. Keeping your practices up to date with the ICHQ8 regulatory guidance issued by the US FDA. This is also a gate way for a smooth ride of product in the different stages of product development stages.
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The pneumatic POSITIVE pressure conveying (or PRESSURE conveying) is dedicated to the transfer of larger quantities of powder or granulates under following conditions:
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Dec’s Big Bag filling stations offer a variety of packaging concepts. These range from simple inflatable gaskets to liner systems which, if necessary, can be integrated into a glove box. The filling systems are of a modular design depending on the process and containment requirements.