INSIGHTS ON SOLID DOSE MANUFACTURING
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![GettyImages-923626190-magnifying-glass-pill-tablets-powder]( "Low-Bioburden Powders For Terminal Sterilisation")
Low-Bioburden Powders For Terminal SterilisationLow‑bioburden powders for reconstitution demand strict microbial control, advanced formulation, and specialised manufacturing, making CDMO expertise vital for modern biopharma.
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![Microvibe]( "A Vibrating Capillary System Enables Fully Automatic Dosing For Powders")
A Vibrating Capillary System Enables Fully Automatic Dosing For PowdersWeight-controlled vibrating capillary technology provides precise microgram powder dosing into capsules or vials while maintaining full operator containment.
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![GettyImages-1370967510 hot cold]( "Overview Of Hot Melt Extrusion And Its Pharmaceutical Applications")
Overview Of Hot Melt Extrusion And Its Pharmaceutical ApplicationsMore than 40% of NCEs face aqueous solubility challenges. Here, we examine how hot melt extrusion addresses solubility, modified release, abuse deterrence, and scale-up across pharmaceutical development.
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![Dalton photo 2]( "How To Handle Intrinsic Product Powder Particles")
How To Handle Intrinsic Product Powder ParticlesPowder filling creates intrinsic particles that interfere with continuous monitoring. Risk‑based strategies must separate product dust from true contamination to meet Annex 1 requirements.
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Bottling Solutions3/4/2025
Explore a bottling solution that is meticulously engineered to adhere to the most stringent pharmaceutical standards, which guarantees that each product is crafted with unparalleled quality and precision.
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5 Advancements In Tablet Compression That Pharma Can't Ignore In 202611/4/2025
New materials, smart automation, and in-press quality control are optimizing tablet compression. These five key innovations are driving efficiency and consistency in solid dose manufacturing today.
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De-Risking Production Of Complex Oral Solid Dosages: Considerations & Key Capabilities7/13/2026
Reduce formulation and scale-up risk with integrated development and manufacturing expertise for complex OSD products.
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The Future Of Sustainable Amorphous Dispersion Development4/15/2026
Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.
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NanoImprove The Performance Of Your Formulations9/24/2024
Learn how Nanoforming can help improve the performance of your molecule by increasing drug loads, improving bioavailability, enhancing drug delivery profiles, and supporting product differentiation.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Aseptic Filling Systems For High Containment Applications]( "Aseptic Filling Systems For High Containment Applications")
Dec offers filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.
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![Encapsulator Natoli]( "Encapsulator For Separation, Filling, And Polishing")
Explore an encapsulator with accurate operation for orientation, separating, filling, closing, and ejecting capsules along with sensors to control powder, pellets, and capsules.
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![PTS Powder Transfer]( "PTS Powder Transfer System®: Dense Phase Powder Conveying")
PTS Powder Transfer System® challenges convention by using both vacuum and pressure to move powders as if they were liquids. This eliminates the need for gravity charging and therefore making multi floor processes a requirement of the past.
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![Manesty Unipress Tablet Press.jpg]( "Used Manesty 34 Station Unipress Tablet")
Used Manesty Unipress rotary table press, 34 station, keyed upper punch guides, 6.5 ton main compression, 1 ton pre compression, B tooled, 11 mm max tablet diameter, 18 mm max depth of fill, single side with force feeder with feed hopper, with control cabinet, up to 247,200 tablets/hour, serial# 15458 84.
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![Natoli scientists]( "Pharmaceutical Preformulation Support Services")
Partner with Natoli Scientific during the earliest stages. Our scientific expertise with state-of-the-art analytical capabilities is ready to take any preformulation challenge.
Natoli scientific has an expertise of handling a wide range of APIs for the development of oral solids. We apply principles of ‘Quality by Design’ to define Critical Material Attributes (CMA), Critical Process Parameters (CPP), Critical Quality Attributes (CQA) and Quality Target Product Profiles (QTPP). Because we believe that understanding material and process as much as possible in the early life cycle of drug product development program is an insurance for further development path. Keeping your practices up to date with the ICHQ8 regulatory guidance issued by the US FDA. This is also a gate way for a smooth ride of product in the different stages of product development stages.
