INSIGHTS ON SOLID DOSE MANUFACTURING
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![Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery]( "Innovations In Orally Disintegrating Tablets For Pediatric Drug Delivery")
Innovations In Orally Disintegrating Tablets For Pediatric Drug DeliveryDelve into the evolving landscape of pediatric dosage forms, with a focus on how ODTs are emerging as a specialized and practical drug delivery system for children.
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![GettyImages-1627638093-glass-beaker-polyvinyl-alcohol]( "Solubility Enhancement Via Amorphous Solid Dispersions")
Solubility Enhancement Via Amorphous Solid DispersionsPolyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
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![GettyImages-2086161977-blister-packaging-liquid-medical-medicine]( "The Future Of Pharma Packaging Trends, Technologies, And Patient-Centric Solutions")
The Future Of Pharma Packaging Trends, Technologies, And Patient-Centric SolutionsPharmaceutical packaging must evolve alongside drug development to ensure stability, safety, and regulatory adherence, utilizing innovative designs to improve therapeutic outcomes and patient accessibility.
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![KinetiSol Amorphic Dispersions]( "Solvent-Free, Fusion-Based Amorphic Dispersion Process")
Solvent-Free, Fusion-Based Amorphic Dispersion ProcessDiscover a solvent-free, fusion-based process that leverages frictional and shear forces to rapidly convert crystalline drugs and polymers into amorphous solid dispersions (ASDs).
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Exploring The Future Of Tablet Compression Across Emerging Industries11/18/2025
Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.
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Orally-Disintegrating Dosage Forms With Taste Masked Multiparticulates7/17/2024
Learn more about our orally disintegrating tablet (ODT) capabilities and how these innovative technologies have the potential to improve acceptance, adherence, and compliance in pharmacotherapy.
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The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
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The Future Of Sustainable Amorphous Dispersion Development4/15/2026
Sustainable amorphous dispersion cuts cost, risk, and timelines by removing solvent waste, simplifying manufacturing, strengthening supply chains, and scaling efficiently to commercialization.
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How To Handle Intrinsic Product Powder Particles3/16/2026
Powder filling creates intrinsic particles that interfere with continuous monitoring. Risk‑based strategies must separate product dust from true contamination to meet Annex 1 requirements.
SOLID DOSE MANUFACTURING SOLUTIONS
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![iStock-1191001266-tablet-pill]( "Oral Solid Dose Formulation Troubleshooting Support Services")
Natoli organization is a reputed leader with more than a half century experience in the tablet manufacturing technology.
We understand tablets better. We are here for serving your needs to overcome challenges associated with commercial manufacturing of solid dosage forms across the globe (North America, Europe, Asia).
Our Natoli scientific team uses holistic approach to understand and solve important tableting problems like capping, lamination, picking, and sticking. We integrate scientific information gathered at material, process, and instrument level to understanding and decode root causes of these common tableting issues.
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![Used Elizabeth Hata RD 10 Station Pharmaceutical Tablet Press]( "Used Elizabeth Hata R&D 10 Station Pharmaceutical Tablet Press")
Used Elizabeth Hata R&D tablet press, model EP200, B/D tooled with 10 station turret, 5 stations each B and D, 16 mm B, 22 mm D max tablet diameter, 17 mm B, 18 mm D max depth of fill, rated up to 6000 tablets/hour, with feed hoppers and feed frames, Machine #81, built 2011.
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![GettyImages-157742535 molecule pfas]( "Build Your Solution: Not Every Molecule Follows A Manual")
A flexible, data‑driven development approach assembles tailored scientific strategies around each molecule, reducing risk, improving manufacturability, and enabling scalable formulation solutions.
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![Fed Equipment - Kikusui tablet press]( "Used Kikusui 36 Station Pharmaceutical Tablet Press: AQUARIUS G-J")
Used Kikusui tablet in tablet press, model Aquarius G-J/DC, 36 station, keyed upper punch guides, B tooled, 100 kN pre-compression, 100 kN main compression, 16mm max tablet diameter, 18mm max depth of fill, rated up to 259,200 tablets/hour, with DC module for core feeder, 4-15mm core depth adjustment, with integrated primary and secondary powder feed hoppers, and core feed hopper, project# 1-6302, built 2009.
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![Natoli - FastLock_450x300]( "FastLok Die Table Surface")
Revolutionize your tablet press with the FastLok™ Die Table Surface from Natoli Engineering. Our exclusive and patented snap-in technology makes changeovers fast, easy, tool-less — getting your press back to full production in minutes.
