INSIGHTS ON SOLID DOSE MANUFACTURING
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![KinetiSol Amorphic Dispersions]( "Solvent-Free, Fusion-Based Amorphic Dispersion Process")
Solvent-Free, Fusion-Based Amorphic Dispersion ProcessDiscover a solvent-free, fusion-based process that leverages frictional and shear forces to rapidly convert crystalline drugs and polymers into amorphous solid dispersions (ASDs).
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![GettyImages-1627638093-glass-beaker-polyvinyl-alcohol]( "Solubility Enhancement Via Amorphous Solid Dispersions")
Solubility Enhancement Via Amorphous Solid DispersionsPolyvinyl alcohol (PVA) is a versatile polymer platform used to enhance solubility through hot melt extrusion. Explore the role it plays in drug solubility, hydrolysis, and thermal behaviors.
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![GettyImages-2002525379-production-solid-dose-capsules]( "Patient Adherence With A Novel Dosage Form")
Patient Adherence With A Novel Dosage FormA sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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![adare ceo interview]( "The Future Of Oral Solid Dose Development And Innovation")
The Future Of Oral Solid Dose Development And InnovationTom Sellig, CEO of Adare, discusses the ongoing relevance of small molecules, oral solid dose development, trends like GLP-1, and innovations like 3D printing in pharmaceuticals.
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The Crucial Role Of Cleaning In Effective VPHP Decontamination For Isolators12/27/2024
Effective isolator cleaning is crucial for vapor phase hydrogen peroxide (VPHP) decontamination. Proper tools, techniques, and training ensure sterility, and regulatory compliance.
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Barrel-Style vs. Standard Dust Cups vs. Bellows: The Essentials Behind Producing The Highest Quality Tablets Free From Contaminates7/30/2024
Dust cups and bellows are essential components in tablet manufacturing, utilized to prevent lubricants from contaminating the tablets.
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Achieving Manufacturing Efficiency In OSD Manufacturing10/16/2024
Gain expert insight into the importance of instrumented tablet presses in assessing formulation properties, the role of tablet cup configurations, and scalability parameters for successful product transfer.
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NanoImprove The Performance Of Your Formulations9/24/2024
Learn how Nanoforming can help improve the performance of your molecule by increasing drug loads, improving bioavailability, enhancing drug delivery profiles, and supporting product differentiation.
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Engineering Challenges Of Designing Pharmaceutical Isolators3/27/2025
Designing pharmaceutical isolators requires navigating complex engineering hurdles, from ensuring chemical compatibility to optimizing airflow and pressure. Explore the critical considerations that guarantee drug manufacturing safety and efficiency.
SOLID DOSE MANUFACTURING SOLUTIONS
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![PFLPowderflex]( "Continuous Conveying And Dosing Of Small Of Powders: PFL Powderflex")
The patented PFL Powderflex provides continuous and precise dosing of small to medium quantities of powder, whether the requirement is for controlled charging of powders into continuous production processes or for predetermined precision dosing.
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![Aseptic-Pharmaceutical-Isolators-from-Franz-Ziel]( "Aseptic Pharmaceutical Isolators From Franz Ziel")
Isolators with product protection as a housing for aseptic processes, e.g., filling, loading and unloading of freeze dryers.
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![3P Innovation - robotic capsule filler 4]( "Robotic Capsule Filling System: R500, R1000")
The robotic capsule filler, part of the Explore Range, integrates our award-winning Fill2Weight technology, eliminating ‘formulation for filling’ steps and reducing pre-clinical timescales, fast tracking to Phase III.
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![Natoli scientists]( "Pharmaceutical Preformulation Support Services")
Partner with Natoli Scientific during the earliest stages. Our scientific expertise with state-of-the-art analytical capabilities is ready to take any preformulation challenge.
Natoli scientific has an expertise of handling a wide range of APIs for the development of oral solids. We apply principles of ‘Quality by Design’ to define Critical Material Attributes (CMA), Critical Process Parameters (CPP), Critical Quality Attributes (CQA) and Quality Target Product Profiles (QTPP). Because we believe that understanding material and process as much as possible in the early life cycle of drug product development program is an insurance for further development path. Keeping your practices up to date with the ICHQ8 regulatory guidance issued by the US FDA. This is also a gate way for a smooth ride of product in the different stages of product development stages.
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![Fuji Marumerizer Spheronizer]( "Used Fuji Marumerizer Spheronizer, Model QJ700")
Used Fuji Paudal Marumerizer spheronizer, model QJ700, stainless steel construction, with 2.0 mm grooved spheronizing plate with plate lift mechanism, jacketed bowl, side discharge with pneumatically operated plug valve, on base, serial 20050, built 1990.
