INSIGHTS ON SOLID DOSE MANUFACTURING
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![Cancer patient oncology unit-GettyImages-1169640471]( "Precision In Miniature: Optimizing Multiparticulate Formulations For Pediatric Oncology")
Precision In Miniature: Optimizing Multiparticulate Formulations For Pediatric OncologyWhen an oral liquid formulation of crizotinib failed pediatric trials due to intolerable taste and irritation, a multiparticulate approach offered a technically demanding but viable path forward.
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![GettyImages-2002525379-production-solid-dose-capsules]( "Exploring The Need For Dose-Flexible Manufacturing")
Exploring The Need For Dose-Flexible ManufacturingRegulatory pressure to study broader dose ranges is reshaping formulation strategy. This executive summary examines how early planning for dose flexibility reduces development risk and clinical delays.
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![Single-Use Containment And Oral Solid Dosage]( "Single-Use Containment And Oral Solid Dosage (OSD)")
Single-Use Containment And Oral Solid Dosage (OSD)Flexible single-use containment systems achieve sub-microgram exposure levels while eliminating cleaning validation downtime for high-potency oral solid dose manufacturing.
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![GettyImages-2179726147 polymer]( "Modeling Polymer Interactions To Improve Amorphous Solid Dispersion Stability")
Modeling Polymer Interactions To Improve Amorphous Solid Dispersion StabilityMolecular dynamics modeling revealed how hydrogen bonding between PVP and Eudragit drives stable amorphous solid dispersion formation, cutting formulation screening time significantly.
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Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months2/26/2026
A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
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How To Achieve Late-Phase Success In Complex OSD Development8/31/2026
Late-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.
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Harnessing Digital Twins To Optimize Tablet Manufacturing10/30/2025
Unlock manufacturing precision with digital twins. Learn how virtual replicas of production systems enable predictive maintenance, streamline scale-up, and ensure consistent product quality in pharma.
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Pharmaceutical X-Ray Counts Capsules And Pills8/15/2025
See how advanced x-ray inspection technology verifies correct pill count, identifies broken capsules, and detects foreign contaminants in pharmaceutical sachet packets.
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From Disruption To Reinvention: The Story Of API-In-Capsule Technology And Its Future8/19/2025
Discover how advanced API-in-capsule technology addresses previous limitations, providing a flexible and efficient path for drug candidates from development to clinical trials.
SOLID DOSE MANUFACTURING SOLUTIONS
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![Dec 3]( "Pharmaceutical Filling Lines With High Containment")
Dec offers pharmaceutical filling lines for both liquids and solids for the aseptic fill-finish process that require high containment equipment.
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![Used IMA Zanasi 6 F Pharmaceutical Capsule Filler]( "Used IMA Zanasi 6 F Pharmaceutical Capsule Filler")
Used IMA Zanasi 6 F Capsule Filler, rated up to 6000 capsules/hour, no change parts, capable of producing 00-5 size capsules, with controls and Siemens PLC, 230 volt, 3 phase, serial# 35071, built 2006.
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![3P Innovation - Fill2Weight]( "Gravimetric Powder Filler: Fill2Weight")
Fills syringes, vials, cartridges, capsules and custom containers at speed with aseptic powder micro-dosing technology.
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![Used ACG Pam AFT LAB Pharmaceutical Capsule Filling Equipment]( "Used ACG Pam AFT LAB Pharmaceutical Capsule Filling Equipment")
Used ACG-Pam Capsule Filler, Model AFT LAB.
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![Dec Group 2]( "Production-Scale Pharmaceutical Filling Systems")
Dec‘s philosophy is to develop customer-specific modules and equipment. Starting with agreed project scope, intensive brainstorm sessions, strong design processes and (customer) reviews, the aim is to deliver an innovative filling solution. During the concept development, risk analysis is an important tool in the decision-making process.
