Solid Dose Manufacturing

INSIGHTS ON SOLID DOSE MANUFACTURING

Reducing Uncertainty In Early Oral Drug Development
Five recurring decision points in early oral solid dose development carry outsized downstream consequences. AI/ML-driven predictive modeling is reframing how teams manage those decisions under API and timeline constraints.
How To Achieve Late-Phase Success In Complex OSD Development
Late-phase OSD scale-up demands more than technical know-how. This paper examines the frameworks, tools, and partnership models that determine whether promising molecules reach commercial production reliably.
5 Hidden Risks In Early-Phase OSD Formulation Development
Early formulation decisions in OSD development carry risks that may not surface until later stages, when the cost of course correction is significantly higher.
Overview Of Hot Melt Extrusion And Its Pharmaceutical Applications
More than 40% of NCEs face aqueous solubility challenges. Here, we examine how hot melt extrusion addresses solubility, modified release, abuse deterrence, and scale-up across pharmaceutical development.

Lipid Formulation Development: Why Softgels Are The Technology Of Choice
8/31/2026

Low bioavailability affects roughly 80% of APIs, yet many drug developers default to standard OSD forms. This paper examines why softgels deserve earlier consideration in formulation strategy.
Enabling Flexibility And Scientific Innovation In OSD Development
8/31/2026

How one clinical-stage CNS biotech navigated early formulation complexity, shifting pipeline priorities, and scalable manufacturing demands through a strategic CDMO partnership.
Converting From A Spray-Dried Dispersion To A KinetiSol Formulation In <5 Months
2/26/2026

A development team quickly turned a low‑bioavailability, high‑burden formulation into a streamlined, clinically improved version, boosting exposure, simplifying manufacturing, and accelerating progress.
De-Risking Production Of Complex Oral Solid Dosages: Considerations & Key Capabilities
7/13/2026

Reduce formulation and scale-up risk with integrated development and manufacturing expertise for complex OSD products.
Segments: Next-Generation Tablet Press Technology
10/7/2025

Segments increase press output by up to 25% and cut setup time by 88%. Learn the benefits, drawbacks, and manufacturing needs of this rapidly growing tablet press technology.

Dedicated To Development: Bend, Oregon's Impact

A facility overview highlighting solubility enhancement and advanced drug delivery capabilities, including a predictive formulation platform and project timeline benchmarks.
Used Pharmaceutical MG2 Planeta Capsule Filling System

Used MG2 Planeta 100 continuous motion capsule filler with touch screen HMI, vacuum system, serial# 4661, built 2010.
Integrated Antibody‑Drug Conjugate Development And Manufacturing

Antibody‑drug conjugate services support development from early clinical stages through commercial manufacturing with integrated analytics, containment expertise, and scalable conjugation capabilities.
Compression Blister Filler System

Forming part of 3P innovation’s Discover Range, this early-stage development unit uses two sets of die punches to compress pellets and seal them within a blister strip. Used predominantly for dry powder inhalers (DPIs), the ultra-compact filler fits on your lab benchtop.
EZ Level Feeder Table Leveling System

Stop wasting time on frustrating, trial-and-error methods to level your tablet press feeder platform. "Close enough" isn't good enough—especially when it leads to excess formulation loss or costly equipment damage. With the Natoli EZ Level™ Feeder Base Leveling System, you can achieve fast, accurate, and repeatable results—every time.