INSIGHTS ON SOLID DOSE MANUFACTURING
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Combining Powdose® And Diffucaps® For Precise Solid Oral Dosing
Combining POWDOSE® and Diffucaps® enables precise, individualized solid oral dosing—improving drug delivery, patient compliance, and therapeutic outcomes in personalized medicine applications.
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Patient Adherence With A Novel Dosage Form
A sprinkle formulation helps patients with tremors or dysphagia take medication more easily, improving adherence, comfort, and care through a novel, FDA-approved oral granule format.
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Innovations, Solutions, And USP <1062> With Scale Up
Optimize tablet compression by simplifying calibration, speeding up changeovers, and utilizing advanced laser inspection to prevent critical punch tip wear and maintain quality.
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Minitablets: Enhancing Safety And Palatability For Pediatric Medicines
Leverage minitablet technology to create flexible, easy-to-swallow, and palatable pediatric formulations that improve adherence and meet evolving regulatory requirements.
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The Importance Of Tablet Density Uniformity10/7/2025
Non-uniform density causes many tablet failures. Learn how optimizing your formulation, tablet proportions, and tooling design ensures proper de-aeration for consistent quality.
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The Role Of Quality By Design In Pharmaceutical Tablet Development7/30/2024
Quality by Design (QbD) ensures efficiency and high standards in pharmaceutical tablet development. Explore how this proactive approach transforms manufacturing processes and enhances product quality.
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Exploring The Future Of Tablet Compression Across Emerging Industries11/18/2025
Many growing industries face universal tablet compression challenges, demanding better tooling, tighter process control, and more integrated data to ensure product consistency and reliable scale-up.
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How High Drug Load Nanocrystalline Tablets Lower Pill Burden3/12/2025
We showcase the development of high drug load nanocrystal based tablets and prove that nanocrystals can match the pharmacokinetic performance of ASDs while reducing the overall pill burden.
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Lower Punch Tip Bending / Buckling11/11/2024
When manufacturing mini-tablets, adjusting punch force ratings is crucial to prevent bending or buckling. The Rankine-Gordon formula offers a safer force rating for microtip tooling.
SOLID DOSE MANUFACTURING SOLUTIONS
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Recent years have shown steady growth in manufacturing sterile, high potent products in the pharmaceutical industry. Antibiotics for intravenous or intramuscular injection in powder form such as Ceftriaxone Sodium for example, need to be produced under sterile conditions.
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Dec provide custom designed isolators for dispensing and/or sampling from various containers such as bags and drums into intermediate packagings or for direct charging into process equipment. These systems offer high containment and a controlled environment offering fast cleaning and drying features allowing for swift product changes.
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Used Kilian rotary tablet press, model T100, 16 station, B/D IPT turret, with (8) B tooled, 16 mm diameter, 16 mm depth of fill and (8) D tooled, 25 mm diameter, 16 mm depth of fill stations in single turret, with additional 9 station IPT B toolded turrent, 42 Kn pre-compression, 65 Kn main compression, keyed upper punch guides, singled sided with force feeder, commission# 706849, built 2002.
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AIM™ Pro Plus Control System Makes Tablet Production Easy
The Natoli AIM™ Pro Plus control system is a flexible software and hardware architecture that is standard on Natoli production tablet presses. This industry-leading package can be retrofitted to almost any production tablet press to increase production, improve tablet consistency, and provide an easier-to-manage production environment. -
Our NP-400 is a 24/7 workhorse that features built in controls and off-the-shelf electronics. A self-lubricated turret and upper and lower cams reduce maintenance costs and provide longer operation time. The NP-400’s compact design is ideal for tablet manufacturers who need a reliable, efficient press to make up to 3,000 tablets per minute.