White Paper

Advances In Aseptic Blow-Fill-Seal Processing: Improve Product Integrity And Patient Safety

By Chuck Reed, Former Chairman of ISPE's Packaging Community of Practice

Advances In Aseptic Blow-Fill-Seal Processing

The latest improvements in aseptic blow-fill-seal technology are providing more streamlined automation of critical B/F/S processing areas, while limiting human intervention and effectively reducing airborne microbial bioburden and particulate levels, and enhancing sterility assurance and patient safety.

Aseptic blow-fill-seal (B/F/S) systems offer a unique combination of flexibility in packaging design, low operating cost and a high degree of sterility assurance. Due to its design and functionality, B/F/S processing inherently produces very low levels of particulate matter, and much of the potential for microbial contamination in its critical areas is mitigated by the absence of human intervention in these areas.

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