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Newsletter | June 26, 2020

06.26.20 -- Bioprocessing: Partners Poised To Meet Demand


Are your purchasing needs still being met?


Purchasing and sourcing – a once familiar process with familiar players – is changing in real-time. We need new tools and approaches to adapt to this new environment. Our Sourcing Centers were created to help you connect with and learn the capabilities of multiple suppliers in an efficient manner. Today, we introduce you to some Bioprocessing providers.

Asahi Synthesis Columns

Mid- to large-scale oligosynthesis has moved from legacy mixed bed reactors to more efficient flow-through column formats. At Asahi Kasei Bioprocess, we bring over a decade of experience to every synthesis column that we deliver, continually improving our platform as we gain valuable feedback from sponsors and contract manufacturers alike.

Cleaning Detergent: Low-Foaming, High-Alkaline Liquid

Keylajet is a low-foaming high alkaline liquid designed for hard to clean soils, grit, grime, slime, grease, buffing compounds, oils, particulates, deposits, chemical and solvents, mold releases, metal oxides, and more.

Biologic Manufacturing Capacity Expansion With Single-Use Technologies — Key Variables To Consider

The following presentation is based on a simulation of a 2 × 2000 L mAb process. The simulation compares a single-use process train (SU) with a comparable stainless steel-based process train (SS), both modelled in a traditional, stick-built facility. 

Bulk Powder Enclosure For Media And Buffer Preparation

Bulk Powder Enclosure for Media and Buffer Preparation designed to provide personnel protection while working with powder substances. The enclosure features include acrylic superstructure, black phenolic base, 20” base cutout with flange/trespa cover/SS ring, hinged door style, top mount fans, and HEPA filtration.

Pharmaceutical Flexible Containment Equipment

DoverPac® Containment Systems, an ILC Dover brand, is the global pioneer of disposable process and powder containment systems.

Used Millipore G450 x 500 52cm Chromatography Column

Used Millipore G450 x 500 52cm Chromatography Column, serial# 450-021 N2, built 2000.

Comparative TOC Rinse-Up Study Of Pharmaceutical Tubing

Total organic carbon (TOC) content provides a measure of the cleanliness of single-use materials and components considered for use in pharmaceutical manufacturing processes. In this technical bulletin, the results of a rinse up study to measure the TOC from four different tubing types is presented. The silicone tubing were each rinsed with deionized (DI) water, which was then sampled and analyzed off-line to determine the TOC content from each.

Enabling Custom Chromatography Solutions For Downstream Processing

The manufacture of complex bio-therapeutics, such as activated proteins or closely related product forms, requires novel purification strategies, which may not always exist. Here we present custom downstream processing solutions, developed in close collaboration with our customers, including a case study covering the single step purification of prothrombin.