Scientific Expertise Delivers Savings To Your Bottom Line

Expedited transfer to a new production site was needed for a commercially launched lyophilized drug. Time lines were critical, as production could not continue at the original manufacturing location, and inventory levels were running low. There was no other source of supply for this molecule, which is indicated for emergency treatment and stocked by both hospitals and national defense inventories. Adding to the challenge was the fact that the existing manufacturing process resulted in significant product losses, averaging 10% per batch due to cake meltback.

Baxter's team in Bloomington, Indiana, designed the following solutions:

• Optimization of the original lyophilization cycle
• Accelerated transfer of the product to the new manufacturing location