Designing A Biomanufacturing Facility Incorporating Single-Use Technologies

By Peter Genest, strategic technology partnerships leader, Cytiva, and John Joseph, engineering project leader, Cytiva

The benefits of adopting single-use technologies in the production of biopharmaceuticals, such as lower capital investment and increased flexibility, are now well documented and widely recognized in the industry. But when building a new facility based on single-use technologies, or incorporating single-use into an existing facility, how do companies ensure they fully realize the benefits?

Facility design is a complex, multi-faceted, multi-step process, and early decisions can cause unforeseen limitations as the project progresses or, later, when further development of the facility is required. Asking the right questions at the outset and having the depth of experience and knowledge to understand the consequences of the answers are vital to establishing the right specifications during the design phase.