Newsletter | May 15, 2012

05.15.12 -- GSK Offers $2.6B For Human Genome Sciences

Pharmaceutical Online Newsletter
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Scientists at Pall recently challenged 0.1 µm-rated filter membrane Pall Fluorodyne® EX grade EDT filters with an elevated mycoplasma challenge concentration and under high differential pressure. To view the impressive results, please visit us here.

From The Editor

More than 11,000 professionals from the pharmaceutical and biopharmaceutical manufacturing, processing, and services industries gathered at this year’s INTERPHEX conference and exhibition at New York City’s Javits Center. With so much expertise in one place, it gave me the perfect opportunity to dig deeper into the issues and innovations that are top of mind in the market today. With camcorder in tow, I navigated my way around the exhibition floor to capture the experts’ takes on today’s manufacturing challenges, get a first-hand look at the latest technologies, and uncover how those technologies are promoting progress within the pharmaceutical manufacturing industry. Check out our INTERPHEX 2012 video gallery to see who expressed their views on single-use technologies, solid-dose manufacturing, continuous processing, and more.

Guest Column

IP Roadblocks And Modified Drug Products
By Jeffrey A. Wolfson, partner, Haynes and Boone, LLP
To address some of the IP roadblocks that can prevent commercialization of a 505(b)(2) drug, a patent clearance is important early and throughout development of a product to evaluate if the "road" ahead remains clear. Read more.

Featured Articles

Ultra High-Shear Mixers Increase Overall Throughput And Efficiency Of Homogenization Processes
By Christine Banaszek, Application Engineer, Charles Ross and Son Company
Several types of mixing systems are utilized for combining raw materials into a premix. There are gentle agitation devices, such as low-speed propellers, turbines, or paddle agitators. Better quality premixes are achieved through the use of high-speed devices such as open-disc saw-tooth blades and high shear rotor/stator mixers.


Greater Cold Chain Controls Through Enabling Technology
By David Bang, CEO, LifeConEx
The term cold chain refers to the time-and-temperature-controlled transportation of temperature-sensitive products from the manufacturer to the end user. The goal of cold chain management is to provide patient safety, product integrity, regulatory compliance, process optimization, and cost optimization.


Updating Palletization To Increase Product Safety
By Rex Lowe, President, iGPS
Some pharmaceutical companies have already moved to streamline and upgrade their supply and manufacturing chains.

Featured Downloads

Brochure: Benchtop Pharmaceutical Roller Compactor — BT 120
With the BT 120 Pharma, Alexanderwerk offers a compactor for use in the pharmaceutical industry, for compacting preparations or active substances.


Brochure: ElizaTest 3+ Vision Tablet Testing System
The Elizabeth-Hata ElizaTest 3+ Vision Tablet Testing System solves the problem of quality control by precisely measuring three critical characteristics: thickness, weight, and hardness, regardless of tablet shape.


From Discovery To Production, Increasing Operational Efficiencies In The Pharmaceutical Industry
The global pharmaceutical industry has been one of the most successful in recent history, and as it matures, the industry is responding to the changes that naturally occur within any market: new technologies disrupting traditional business models, growth of generic competition, and a search for high- growth markets.


A Robust Cold Chain With A Proactive Quality Improvement Approach
Grifols is a global healthcare company that produces plasma-derived medicines for people who have rare and life-threatening disorders, such as hemophilia, immune deficiencies, and genetic emphysema.

Industry News

GSK Offers $2.6B For Human Genome Sciences
GE Healthcare Life Sciences Acquires Xcellerex
Watson Confirms Lialda® Patent Challenge
FDA Recommends Approval Of Tofacitinib For Active Rheumatoid Arthritis
SOCMA's BPTF Welcomes House Committee Passage Of FDA Reform Act
New HIV Vaccine Nasal Administration A Success
Quanticate Expands Operations In India
Protein Mobility Using Laser Doppler Electrophoresis At IACIS 2012
FDA Issues Alert On Potential Dangers Of Unproven Treatment For Multiple Sclerosis
Liquidity Services, Inc. To Acquire GoIndustry DoveBid
View more headlines

 

"Advances In Pharmaceutical Processing" (Complimentary Technical Seminar)

"Advances In Pharmaceutical Processing" (Complimentary Technical Seminar)

A one-day course examining a wide variety of important pharmaceutical processing topics and trends. This seminar offers an objective technical overview and introduces participants to methods of both improving current operations and utilizing new process technologies. Course material is suitable for scientists, engineers, production, and manufacturing personnel, researchers, formulation scientists, product development, and process transfer personnel.

May 22, 2012: POINTE-CLAIRE, QUEBEC, CANADA
May 24, 2012: RESEARCH TRIANGLE PARK, NORTH CAROLINA, USA
Online Registration Form

SPONSORS: ProSys, K-Tron, ChargePoint, FPS (Food Pharma Systems), Quadro, and Fitzpatrick
Learn more: Download Seminar Flyer (PDF)

Spotlight On Mixing And Blending

Gravimetric Continuous Blenders
Premier ProRate™/Gravimetric blenders consist of one to eight ingredient feeders and a microprocessor-based controller.

Achema Outdoor Area / 1A27

Apply High-Speed Powder Induction To Eliminate Dusting In The Mixing Area
When poured from one open vessel into another, lightweight solids easily become airborne and can require extensive clean up.

Quadro Ytron™
With the Quadro Ytron line of mixers, dispersers, and emulsifiers there’s now a proven, viable alternative that removes obstacles more efficiently. This unique, in-line technology maximizes yields, creating high-quality dispersions and emulsions by applying the required shear to all the material in a quick, single pass.

Achema Hall 5 / Stand C12

Pharma Mixer P 300 - P 1800
DIOSNA mixer-granulators are used by leading companies worldwide and guarantee the safe and reproducible production of high-quality granules — even with the most difficult recipes and differing fill volumes.

Achema Hall 3.1 / Stand D4

Case Study: Dramatic Yield Increase Through Use Of Antisegregation Technologies
Custom Powder Systems provides a unique solution to improve yields from less than 75% to over 98%.

Setting New Standards In Disintegration Testing
The DisiTest 50 automatically detects the disintegration time of tablets and capsules, in full compliance with current Pharmacopeia. Visual monitoring of the disintegration process by the operator is not required.
Browse the download library

Industry Webinar

Reduce Manufacturing Costs And Improve Quality With The Proper Assembly Lubricants
Reduce Manufacturing Costs And Improve Quality With The Proper Assembly Lubricants
June 6, 2012 | 1:00 PM EST

Rubber, both natural and synthetic, is a core material in many manufacturing industries. Tight-fitting rubber components can slow production and affect quality and safety. International Products Corporation manufactures assembly lubricants that help reduce costs from damaged parts and improve assembly quality, as well as worker safety. Learn more.

Bulletin Board

Bio-G Webinar: Capacity Planning In Biomanufacturing — Effectively Managing Uncertainty
Bio-G Webinar: Capacity Planning In Biomanufacturing — Effectively Managing Uncertainty
Americas: May 30, 2012 | 1:00 PM PDT, 4:00 PM EDT
Europe: May 30, 2012 | 3:00 PM GMT, 4:00 PM CET

Capacity planning for new molecules in biotech is fraught with uncertainty. Supply constraints, unknown titers, number of patients and dosing, as well as probability of technical success (PTS), make capacity planning difficult. This webinar will outline a number of approaches to understanding and managing the uncertainty associated with capacity planning. Learn more.

Featured Products And Services

Aseptic Processing Pressure Vessels
Aseptic Processing Pressure Vessels

Product Details
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Servolift LLC

Clinical Trial Cold Chain Logistics
Clinical Trial Cold Chain Logistics

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World Courier Inc.

Temp-Assure® Customized Solutions
Temp-Assure® Customized Solutions

Product Details
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FedEx Custom Critical

Vibratory Tablet Deduster Metal Check: Combination Unit
Vibratory Tablet Deduster Metal Check: Combination Unit

Product Details
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Kraemer US LLC

Pharmaceutical Cleanroom Panels
Pharmaceutical Cleanroom Panels

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Terra Universal

Compliance Support: Validation Toolkit
Compliance Support: Validation Toolkit

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Siemens Industry, Inc.

MC5 Multifunction Calibrator
MC5 Multifunction Calibrator

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Beamex

Pneumatics
Pneumatics

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Bürkert Fluid Control Systems

Cirrus 2 Quadrupole Mass Spectrometer
Cirrus 2 Quadrupole Mass Spectrometer

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Micromeritics Instrument Corporation

Pharma Chemicals: Custom Manufacturing
Pharma Chemicals: Custom Manufacturing

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DSM Pharmaceutical Products

Particle Characterization System: Morphologi G3
Particle Characterization System: Morphologi G3

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Malvern Instruments

Alcotabs: Critical-Cleaning Detergent Tablets
Alcotabs: Critical-Cleaning Detergent Tablets

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Alconox, Inc.