Article | December 7, 2016

How Important is Compaction Dwell Time in Solid Dose Manufacturing

Source: Natoli Engineering Company, Inc.

Robert Sedlock


When developing a new formulation, scientists are equipped with a small scale tablet press to study and understand their product’s tablet-ability. These small scale systems are very useful at the research level but do not always successfully transfer to larger scale manufacturing machines where compaction dwell time will be a critical component. Ideally, developing products on a manufacturing press eliminates the transfer challenges, but the amount of powder required to operate such a machine is very high and not cost effective.

Natoli Engineering Company, Inc.