Influence Of Silanol Content, Humidity, And Temperature On Efficacy Of A Silica Based Carrier

Source: Grace

By Yogesh Choudhari, Upendra Reddy, and Fred Monsuur, Grace

Recently, silica based carriers have been widely used for the adsorption of oily and lipid based formulations. Using silica as adsorbent, liquid self emulsifying drug delivery systems could be formulated in tablet or capsule oral dosage form. For this application, an ideal carrier is one which possesses high adsorption capacity and immediate desorption or release at desired site. Three different types of carriers like Granulated fumed silica (GFS) Syloid® XDP-Mesoporous silica gel (MSG) and Magnesium aluminum silicate (MAS) were selected for this study.