Drug manufacturers seeking alternative methods for a safe and reliable approach to drug delivery should consider blow-fill-seal technology, as it offers several benefits over traditional glass packaging. Blow-fill-seal not only addresses the challenges associated with using glass syringes and vials, but the higher automation offers an opportunity to reduce costs, speed up production, and lower labor requirements.
The latest generation of aseptic blow-fill-seal (B/F/S) machines incorporate dedicated isolators adapted specifically for insertion applications. This new addition to the aseptic B/F/S system has not only streamlined the insertion process, but has provided a higher level of sterility assurance for products with tip-and-caps and rubber/silicone stoppers inserted under aseptic conditions.
The latest improvements in aseptic blow-fill-seal (B/F/S) technology are providing more streamlined automation of critical B/F/S processing areas while limiting human intervention and effectively reducing airborne microbial bioburden and particulate levels and enhancing sterility assurance and patient safety.
Weiler Engineering presents an example of an automatic cap welding machine for welding Euro, Inso, and similar style caps to large-volume parenteral (LVP) bottles. The video features 500 mL LVP Bottles of LDPE resin produced on the model 640 blow-fill-seal system.