Newsletter | August 30, 2021

08.30.21 -- Manufacturing APIs And Fermentation-Based Products

Important Considerations For CMO Selection
Post COVID-19, The Pharmaceutical Supply Chain Will Further Shift From A Global To A Regional Model

The pandemic has highlighted vulnerabilities in the global supply chain that may be triggered by future logistical or political disruptions. To reduce risk, initial steps are being taken to review how to increase local production capacities and tighten potential supply chain gaps.

Optimizing The Development And Upscaling Of API/HPAPI And Fermentation Projects

Discover some of the key expectations of customers who are reviewing CMOs to support the development and upscaling of their next major project.

API/HPAPI Manufacturing Considerations
Highly Potent APIs Are Becoming More Potent And Complex

Dr. Andreas Meudt, the global head of exclusive synthesis for Evonik, shares his thoughts on key growth trends for HPAPIs and why more pharma companies are outsourcing their production to contract specialists.

Developing The Highest Purity Polyethylene Glycols (PEGs) And Methoxy PEGS (mPEGs) For Pharmaceutical Applications

Few suppliers of standard or custom PEGs and mPEGs have the necessary competencies to address quality and purity requirements or to overcome other technical manufacturing challenges, such as the reliable handling of ethylene oxide, organic solvents, and initiators.

Advantages In The Continuous Manufacturing Of APIs And Intermediates Under cGMP Conditions

Several drug products utilizing continuous manufacturing processes have been approved by the FDA, with many others in clinical development. Review the challenges and opportunities for the use of continuous manufacturing for APIs and intermediates.

Why A Modular Continuous Pilot Plant Might Be Your Flow Chemistry Solution

About the size of a shipping container, a modular continuous pilot plant features a highly flexible modular configuration that can enable the use of a wide range of reactor types within a small and highly cost-effective footprint.

Fermentation-Based Manufacturing Considerations
Key Factors In The Outsourcing Of A Microbial Fermentation Project To A CMO Partner

Over the last decade, the potential of fermentation-based manufacturing has dramatically expanded, due to advances in synthetic biology and genetic engineering. Examine the key trends and scale-up challenges to manufacturing a substance via fermentation.

Emerging Industry Trends And CMO Solutions For Protein Fermentation

To meet growing market demand for the use of protein-based products that have a sustainable ecological footprint, substantial efforts are now underway to utilize microbial fermentation-based processes to transition animal-derived sources such as meat, skin, silk, milk, and eggs.

Recombinant Collagen Made Via Fermentation Can Address Key Unmet Market Needs For Safety, Sustainability, And Acceptability

The production of recombinant collagen made via fermentation-based processes addresses market needs for collagen that is safe, sustainable, reproducible, and acceptable to consumers.