10.30.20 -- Particle Engineering For Drug Delivery To The Lungs

Spray drying and jet milling are commercially viable engineering processes for the development of respirable drug products. This article presents a case study that explores the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol.

This webinar explores the technical issues that must be examined for successful development of effective capsule-based inhaled drug products. Key design considerations are discussed, including formulation attributes, technology selection (e.g., spray-drying, micronization), and capsule and device considerations. 

Inhalation-based drug products play a critical role in addressing the rising incidence of respiratory diseases around the globe. Particle engineered-based formulations are key in designing and developing effective dry powder inhaler (DPI)-based drugs. This article discusses key parameters for choosing the right particle engineering approach to meet DPI target product profiles.