Medication adherence is influenced by several factors — the method of treatment, healthcare accessibility, a patient’s socioeconomic status, and the palatability and swallowability. For pediatric populations, adherence can be complicated by considerations such as a child’s ability or willingness to accommodate any bitterness or texture issues.
There are several technologies available for microencapsulating drugs. Finding a contract development and manufacturing organization (CDMO) that possesses the experience and expertise necessary to optimize a drug’s efficacy and manufacturing during formulation is integral to a product’s ultimate clinical and commercial success.
Taste masking, swallowability, and palatability are integral considerations for oral drug formulations. Ensuring these can serve to increase patient acceptability and adherence, which can bolster regulatory acceptance and commercial potential. Gain critical insights into strategies and techniques for optimizing taste masking during the formulation process.
This paper proposes the use of a pediatric quality target product profile (pQTPP) as an efficient tool to facilitate early planning and decision-making during the children-centric formulation design for new chemical entities, or to repurpose/reformulate off-patent drugs.
Originally presented by Srinivasan Shanmugam, Senior Director Pharmaceutical Sciences, Adare Pharma Solutions, this slideshow reviews the pediatric population and their needs, the significance of taste masking, and taste masking strategies.