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R&D To Pharmaceutical Product: How To Reduce Costly Scale-Up Problems

Source: Natoli Engineering Company, Inc.
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By Chuck Kettler, Director, Natoli Scientific of Natoli Engineering Company, Inc.

When scaling a new drug formulation from the development side of R&D into manufacturing, there is often a reality check with respect to process scale- up and performance of the formulation at production levels. Problems with capping/lamination and sticking/ picking are often first realized when a formulation is introduced to a level of compression required to supply market demand.


Natoli Engineering Company, Inc.