In this guide you'll find a method-by-method review of critical cleaning procedures. Following are specific examples of applications for detergents to clean all processing surfaces, difficult residues, and different types of processing equipment without leaving interfering residues.
The use of aqueous cleaning in pharmaceutical manufacturing can provide numerous benefits in terms of efficacy, minimal surface contact, reduced residue potential, and easier cleaning validation.
Getting the best results from any cleaner requires proper mixing and cleaning procedures. This article includes mixing directions for aqueous cleaning detergent and methods for monitoring performance.
A faster and more efficient method to remove silicone grease from syringes is to use very hot water for cleaning and very hot water for rinsing. Hot water for rinsing (roughly the same temperature as washing) will avoid breaking the emulsions that form in the wash solution, which can result in redepositing silicone grease.
The use of aqueous cleaning in medical device manufacturing can provide numerous benefits in terms of efficacy, minimal surface contact, reduced residue potential, and easier cleaning validation.
Per Center for Disease Control (CDC) guidelines for cleaning and disinfecting viruses and other pathogens, any form of disinfection necessarily follows cleaning. The process of cleaning will remove any residues that might shield any virus or pathogen from the disinfection step that comes next. Disinfection can be done with bleach solutions, 70% alcohol solutions, or other products with EPA-approved emerging viral pathogens claims.
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