Newsletter | September 25, 2021

09.25.21 -- Solid Dose Manufacturing Product Showcase


Pharmaceutical Online’s Product Showcase — your trusted resource for featured equipment and services specific to the solid dose manufacturing space.

Seal Integrity Testing Of Blister Packaging

With the AMI and its optical emission spectroscopy, Pfeiffer Vacuum has introduced a method with lower detection limits compared to any other method that uses gas trapped in the cavity.

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Pfeiffer Vacuum Inc.
Pharmaceutical Cleanrooms For Oral Solid Dose Process Equipment And Manufacturing
Pharmaceutical oral solid dose and sterile manufacturing operations are rigorously scrutinized for integrity and consistency to maintain patient safety. Accordingly, pharmaceutical process equipment supporting or controlling sterile operations is designed to meet strict regulatory guidelines and design requirements.
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AES Clean Technology, Inc.
Oral Solid Dose (OSD) Contract Packaging Services
With ample available capacity, Ropack Pharma Solutions provides the efficiency of five bottling lines with quick changeovers, online validated fill accuracy, and the flexibility to accommodate small lots to commercial runs for the bottling of tablets, capsules, and powders.
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Ropack Pharma Solutions
Seal Inspection Technologies For Tablets And Capsules Packaging
Nondestructive package testing of multicavity blisters — completely tool-less for different blister formats.
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PTI Packaging and Inspection Systems
Tablet Press Feeder For Die Wall Lubrication
The Coperion K-Tron PH line of pharmaceutical design loss-in-weight tablet press feeders are engineered for accurate dispensing of powder lubricants directly to the tablet press punch and die wall surfaces. The Coperion K-Tron tablet press feeder offers an automated, nearly constant feed rate, providing uniform coating of the tablet tools and avoiding sticking problems. This external lubrication provides many additional potential benefits to manufacturers of tablet dosage forms, including improving tablet hardness and dissolution properties. The Coperion K-Tron patented SFT load cell technology, coupled with a venture-type dispersion method, produces consistent and measurable flow of lubricant powder.
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Coperion & Coperion K-Tron
API Manufacturing And Material Handling Equipment

API manufacturing requires powder handling in a GMP and contained manner. Similar to chemical manufacturing, operations such as charging powders into a chemical reactor, emptying a centrifuge, or charging and discharging a dryer are standard processes.

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Dec Group
Single-Use Containment Systems For Granulator Equipment
In the pharmaceutical industry, granulation is used to create bonds between particles as part of the oral solid dosage manufacturing process. ILC Dover supplies a family of products that support contained granulator operation and features validated containment technology, clear film, and the ability to retrofit to existing equipment design.
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ILC Dover
Cleaning Detergents For Oral Solid Dose (OSD) Manufacturing
Keylajet is a low-foaming high-alkaline liquid designed for hard-to-clean soils, grit, grime, slime, grease, buffing compounds, oils, particulates, deposits, chemicals and solvents, mold releases, metal oxides, and more.
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Alconox Inc.
SP Hull LyoConstellation Development, Pilot, And Production Freeze Dryers
LyoConstellation represents a brand-new range of development and pilot freeze dryers, configured to order for faster delivery and specifically designed for aseptic operation. When handling high-value APIs, and with a need to bring products to market as quickly and safely as possible, LyoConstellation addresses early-stage development under aseptic and low particle controlled conditions. The product therefore behaves in the same manner once it is ready for scale-up and then commercialization. Powerfully equipped as standard to provide higher capacity, broadened equipment capability, and expanded design space, LyoConstellation models S10, S20, and S30 are all equipped with the same advanced suite of Line of Sight technologies as other SP R&D freeze dryers, providing data for full process and product lifecycle management. The LyoConstellation range also fully integrates with SP filling line and semi-automatic loading systems, offering best manufacturing freeze-drying practices, to achieve faster product progression from development to commercialization.
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SP Scientific Products
Tablet Compression Tooling

A global leader in manufacturing, Natoli Engineering Company delivers superior tablet compression tooling. Every punch and die is produced from quarantined steel and tested for hardness and exact chemical composition by stringent quality specifications. 

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Natoli Engineering Company, Inc.
Used Korsch XL 400 Two-Layer Tablet Press, 35/29 Station
Used Korsch XL 400 two-layer rotary tablet press, 35 station with B turret, 29 station with D turret. Serial# K1500036, built 2001.
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Federal Equipment Company
Checkweigher For Tablets And Capsules

The HC-A-MI is the perfect automated system for continuous and accurate weighing of ultra-lightweight parts (for example, stick packs) in the milligram range. Product infeed is product-specific and individually managed.

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Containment Equipment For Pharmaceutical Contract Manufacturing Organizations
Contract development and manufacturing organizations (CDMOs) provide a comprehensive, single-source drug development and commercial manufacturing solution that requires unyielding safety and processing standards. We believe that understanding the importance of our client’s process is the key to a successful partnership.
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Flow Sciences Inc.
Metal Detection Systems: Tablets And Capsules
Designed to meet the exacting standards and regulations of the pharmaceutical industry, METTLER TOLEDO Safeline pharmaceutical metal detectors provide the ultimate solution in fully integrated product inspection and rejection systems for tablets, capsules, powders, and granules. Our metal detection systems are designed to detect all metal contaminant types, including ferrous, nonferrous, and even the most difficult-to-detect nonmagnetic stainless steels.
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Mettler-Toledo Product Inspection
High-Shear Mixers For Pharmaceutical Oral Solid Dose (OSD) Processing
Ross manufacturers the world’s broadest line of rotor/stator pharmaceutical high-shear mixers.
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Charles Ross and Son Company
Pharmaceutical Batch Mixers
A Silverson high-shear batch mixer doesn't simply mix; it emulsifies, homogenizes, solubilizes, suspends, disperses, and disintegrates solids. Each mixer, with its precision engineered Silverson rotor/stator workhead, far outperforms conventional mixers, cutting processing times by up to 90%, improving quality, product consistency, and process efficiency.
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Silverson Machines, Inc.
Oral Solid Dose (OSD) Cleanroom Environmental Contamination Monitoring
Monitor your viable and nonviable particles according to the most recent regulatory requirements. Count, report, document, and manage your pharmaceutical environmental monitoring data meeting 21 CFR Part 11 data integrity requirements.
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Particle Measuring Systems
Continuous Monitoring Of Cleanrooms And Isolators
FMS, BioTrak, portable, remote, and environmental sensors.
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TSI Incorporated
Moisture Determination Of Dry Product
Residual product moisture content is a critical parameter when considering the stability and shelf life of lyophilized pharmaceutical product, sterile powders, or solid dosage product. Lighthouse offers complete solutions for moisture determination of dry product.
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Lighthouse Instruments
Pharmaceutical Asset Management And Reliability Services
Asset management and reliability (AMR) focuses on preserving asset functions. These functions are determined by our clients’ business strategy. The focus is on producing products that conform to consumer needs in the most efficient and cost-effective manner. While conditions vary, the common factor with a manufacturing process is reliability. We help our clients determine which best practices are applicable in their industry and how best to deploy them.
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