One in 17 people will develop dysphagia, or difficulty or discomfort in swallowing, in their lifetime. Even for those with a healthy swallowing function, it can be a challenge to swallow solid oral medications.
Coacervation is a microencapsulation technique that offers several unique benefits to developers interested in working with challenging and/or bitter-tasting molecules, managing a product’s life cycle, and even accelerating development timelines.
The challenge was developing a taste masked, convenient dosage formulation of a very bitter API for patients two years old and older undergoing treatment of HIV infection.
A European-based pharmaceutical company wanted to improve their pancreatic enzyme product (PEP) delivery to patients who have difficulty swallowing several capsules a day — especially children with cystic fibrosis and other conditions.
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