Q&A

Unexpected SEC Results – Can It Be Improved?

Source: Cytiva

By Jon Lundqvist, Scientist at Cytiva

GE_Chromatography_media

Sometimes your size exclusion chromatography (SEC) results don’t look like you want them to. Fix issues like poor resolution, peak tailing and fronting with the tips in this FAQ.

  • How can I optimize the running conditions to optimize resolution in my SEC runs?
  • What causes peak tailing?
  • What causes peak fronting?
  • I do not get the resolution I need with my SEC column. What to do?

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