Since 1965, AST has been delivering innovative solutions – many of which were industry firsts and have since become industry standards. AST has always understood that our customers serve demanding and oftentimes unpredictable markets. We also understand that “flexibility is the antidote to uncertainty,” and as your partner, AST consistently seeks to deliver innovative solutions that are robust, yet flexible. AST is a technology leader specializing in advanced aseptic filling and closing systems. Our focus is to provide innovative and flexible products that satisfy the most challenging product and regulatory requirements for the Pharmaceutical and Biotechnology industries. AST’s spectrum of products includes semi-automated to completely automated and integrated cGMP manufacturing systems for processing vials, syringes and cartridges. To discover more about our products please select a product category.


AST’s GENiSYS® and semi-automated systems allow scientists and engineers to characterize their drug product and develop data-driven manufacturing processes in more meaningful and scalable ways.

AST provides dependable aseptic filling equipment proven within the pharmaceutical industry, but right-sized for the unique requirements of the compounding pharmacy environment.

AST aseptic filling products address the unique processing requirements to gently care for biologic products during the fill-finish process.

AST's GENiSYS® aseptic filling and closing machine has an innovative dosing system that ensures that each container processed has the exact amount of drug within the container.

AST’s GENiSYS® and ASEPTiCell® aseptic filling and closing systems have innovative capabilities that maximize product yield and product quality.

AST’s line of aseptic and syringe filling and closing machines provide adaptive fill-finish capabilities to ensure that any contract manufacturing organization has the right capabilities for any vial, syringe or cartridge application.

AST machines are specifically designed so that your bioligics are handled with care and monitored closely.

AST’s ASEPTiCell® is a flexible fill/finish systems that can efficiently process medium-sized clinical and commercial batches while meeting all cGMP requirements for cleanliness and sterility.

Today’s injectable drug products require flexible fill/finish systems that can efficiently process medium-sized clinical and commercial batches while meeting all cGMP requirements for cleanliness and sterility.

AST’s GENiSYS® C is an advanced, yet compact, filling and closing system for automated processing of nested, custom and ready-to-use vials, syringes, and cartridges. With many features typically found in large scale filling machines, the GENiSYS C’s compact footprint makes this system ideal for use in small scale filling applications, including R&D, process development, engineering runs, niche product manufacturing, and even cGMP clinical and small-batch commercial manufacturing.

AST’s GENiSYS® R has a unique blend of automated capabilities to ensure your sterile products, whether clinical or commercial, are processed in strict accordance with cGMP requirements. The system has the flexibility to adapt to your process requirements and container options alike, and its ability to process all ready-to-fill vial, syringe, and cartridge formats allows you to bring drug products to market cost-effectively.

AST’s line of table-top machines, GENiSYS® Lab, are ideal systems for drug product development and cGMP production applications. Each system is designed to automate the critical aseptic operations for vial, syringe and cartridge processing to reduce contamination risk and product variability. These table-top systems are engineered to have complete compatibility with cleanroom environments, including Laminar Air Flow Hoods, Bio-Safety Cabinets and aseptic isolators.

AST’s Container Closing System (CCS) is a benchtop, semi-automatic machine that provides complete and accurate control of the syringe and cartridge closing process. The Container Closing System is able to close syringes or cartridges using both vacuum and vent-tube methods for a wide range of container sizes quickly and easily with only a few format part changes.

AST’s Container Filling System (CFS) is a bench-top, semi-automatic machine used for the filling of pre-filled syringes and cartridges, and the filling and stoppering of vials and bottles. The system is designed to meet the demanding requirements for small batch processing of sterile injectable products.

AST's Vial Sealing System (VSS) is a benchtop, semi-automatic machine used for sealing or capping pharmaceutical vials and bottles with aluminum caps. The VSS provides complete and precise control of the container sealing or capping operations to ensure the highest quality vial seal. The system’s versatility allows for the processing of a wide range of vial or bottle sizes and finishes and is ideal for small batch processing of sterile pharmaceutical and biotechnology products.


Automated Systems of Tacoma, Inc.

4110 South Washington Street

Tacoma, WA 98409


Phone: 253-475-0200

Contact: Brittany Hoff


  • ASEPTiCell® Robotic Filling And Finishing

    AST’s ASEPTiCell® provides flexible, robotic filling and finishing of vials, syringes and cartridges for small to medium clinical and commercial batches. AST’s modular design allows the ASEPTiCell to be built to your specification without the cost and risk of customization.

  • GENiSYS® R Robotic Handling

    The GENiSYS® R offers a unique blend of automated capabilities to ensure your sterile products are processed in strict accordance with cGMP requirements. With robotic handling available from bag opening to vial sealing, and integration with barrier technologies, your product is protected from contamination through all stages of processing. 

  • Maximize Productivity With The GENiSYS® R

    GENiSYS® R provides ultimate flexibility for processing ready-to-use vials, syringes and cartridges on a single machine. Highly reliable robotics and recipe driven changeovers allow for complete format changes in as little as 30 minutes. Maximize productivity and return-on-investment with the GENiSYS R.

  • GENiSYS® Lab Semi-Automatic Systems

    AST’s GENiSYS® Lab semi-automatic systems are ideal for drug product development and cGMP production applications. Each system automates the critical aseptic operations for vial, syringe and cartridge processing to reduce contamination risk and product variability. GENiSYS Lab offers a perfect balance between automated features, size and affordability without compromising quality, safety and ease of use.

  • How Robotics Offer Answers To Today’s Pharmaceutical Manufacturing Challenges

    What are the COVID-19 effects on pharmaceutical manufacturing? Can we expect “onshoring” strategies following the crisis? Is the general opinion about robotics improving? Watch this webinar to learn more about where and how robotics add value and solve problems.  

  • The Advantages Of Robotics In Aseptic Fill Finish

    As you move into a future of diverse pipelines that present both great opportunities and challenges, consider utilizing a flexible solution like robotics that can be rapidly implemented into your facility.

  • How Robotics Offer New Answers To Today's Challenges In Pharma

    We are proud to announce that AST president and CEO Joe Hoff will be a panelist in the upcoming webinar "Pharmaceutical industry: How robotics offer new answers to today's challenges," hosted by Staubli.

  • Bridging The Divide - Streamline The Process Development & Tech Transfer Process

    Preparing drug products for tech transfer can be a daunting task. Traditional process development practices tend to be labor intensive, difficult to scale to a manufacturing environment, and gathering the critical process data to make informed decisions can be a challenge. This article describes how the advantages of AST's GENiSYS® system can streamline the tech transfer process by enabling efficient drug development activities and process data collection.

  • February 26 Webinar: Bringing Flexibility And Precision To Fill Injectables Using Robots

    The upcoming 30-minute webinar presents an overview of the company’s mission and values, along with a detailed product overview highlighting how AST’s machines respond to the unique challenges found across a variety of filling applications.

  • Delivering Flexibility Without Complexity

    Next generation drug products are more targeted and patient specific by nature causing batch sizes to be much smaller. This paradigm shift paves the way for more flexible manufacturing solutions.

  • Robotics, Isolators & Restricted Access Barrier Systems (RABS)

    The aim of advanced aseptic processing is the elimination and absolute control of all sources of contaminations - most importantly, human generated contamination. Robotics and isolator-barrier systems will be the core technologies in meeting this endeavor.