ABOUT AUTOMATED SYSTEMS OF TACOMA

Since 1965, AST has been delivering innovative solutions – many of which were industry firsts and have since become industry standards. AST has always understood that our customers serve demanding and oftentimes unpredictable markets. We also understand that “flexibility is the antidote to uncertainty,” and as your partner, AST consistently seeks to deliver innovative solutions that are robust, yet flexible. AST is a technology leader specializing in advanced aseptic filling and closing systems. Our focus is to provide innovative and flexible products that satisfy the most challenging product and regulatory requirements for the Pharmaceutical and Biotechnology industries. AST’s spectrum of products includes semi-automated to completely automated and integrated cGMP manufacturing systems for processing vials, syringes and cartridges. To discover more about our products please select a product category.

FEATURED PRODUCTS

Having the right balance of capacity and capabilities in all market conditions is the struggle that Contract Manufacturer Organizations face daily. Add to it the cost and complexity of maintaining a suitable parenteral manufacturing facility, the risks can be high. With constantly evolving parenteral market needs, having flexibility while achieving high utilization is key to long term success. To support these challenges, AST’s line of aseptic and syringe filling and closing machines provide adaptive fill-finish capabilities to ensure that any contract manufacturing organization has the right capabilities for any vial, syringe filling or cartridge application.

Pharmaceutical companies, researchers, scientists, and medical professionals work tirelessly to create and bring crucial vaccines and immunizations to the market. Understanding key product characterization details such as sterilization, secure packaging and optimal process conditions for manufacturing are necessary elements of the vaccine development process. The right vaccine development machines and filling equipment minimize obstacles to gaining this poduct and process knowledge. To aid the vaccine development process, AST’s vaccine filling machine, GENiSYS®C allows scientists and pharmaceutical companies to differentiate their vaccine product and develop data-driven manufacturing processes in more meaningful and scalable ways.

ASEPTiCell is integrated with isolator-barrier technologies to fully enclose and tightly control the aseptic environment for ideal conditions for processing sterile drug products. The system can be configured with a Restricted Access Barrier System (RABS) or an aseptic isolator to provide uninterrupted aseptic conditions during production. With isolator integrated systems, the ASEPTiCell is completely compatible with repeated in-situ bio-decontamination using hydrogen peroxide to further enhance the sterility assurance of the system.

Cell and gene therapies have increased in popularity in recent years, and thanks to their ability to provide one-time treatments these therapies will play a significant role in treating some of the world's most challenging diseases. These drug products treat patients afflicted with genetic disorders and cancers by targeting the source of disease and altering its genetic makeup to eliminate its cause or symptoms. These therapies are expensive and complex and have been proven effective in numerous cases, but they present a challenge in producing them at scale and at a reasonable cost.

With many of the blockbuster biologic drugs of the ’90s are coming off of patent, companies are racing to provide a clinically similar alternative to these pioneering products. Like any biologic drug, they require care and attentiveness throughout the manufacturing process. Therefore, it is necessary to maintain aseptic conditions throughout the production process of these drug products.

AST’s GENiSYS® and semi-automated systems allow scientists and engineers to characterize their drug product and develop data-driven manufacturing processes in more meaningful and scalable ways.

AST provides dependable aseptic filling equipment proven within the pharmaceutical industry, but right-sized for the unique requirements of the compounding pharmacy environment.

AST aseptic filling products address the unique processing requirements to gently care for biologic products during the fill-finish process.

AST's GENiSYS® aseptic filling and closing machine has an innovative dosing system that ensures that each container processed has the exact amount of drug within the container.

AST’s GENiSYS® and ASEPTiCell® aseptic filling and closing systems have innovative capabilities that maximize product yield and product quality.

AST's line of aseptic and syringe filling and closing machines provide adaptive fill-finish capabilities to ensure that any contract manufacturing organization has the right capabilities for any vial, syringe or cartridge application.

AST machines are specifically designed so that your bioligics are handled with care and monitored closely.

AST’s ASEPTiCell® is a flexible fill/finish systems that can efficiently process medium-sized clinical and commercial batches while meeting all cGMP requirements for cleanliness and sterility.

Today’s injectable drug products require flexible fill/finish systems that can efficiently process medium-sized clinical and commercial batches while meeting all cGMP requirements for cleanliness and sterility.

AST’s GENiSYS® C is an advanced, yet compact, filling and closing system for automated processing of nested, custom and ready-to-use vials, syringes, and cartridges. With many features typically found in large scale filling machines, the GENiSYS C’s compact footprint makes this system ideal for use in small scale filling applications, including R&D, process development, engineering runs, niche product manufacturing, and even cGMP clinical and small-batch commercial manufacturing.

AST’s GENiSYS® R has a unique blend of automated capabilities to ensure your sterile products, whether clinical or commercial, are processed in strict accordance with cGMP requirements. The system has the flexibility to adapt to your process requirements and container options alike, and its ability to process all ready-to-fill vial, syringe, and cartridge formats allows you to bring drug products to market cost-effectively.

AST’s line of table-top machines, GENiSYS® Lab, are ideal systems for drug product development and cGMP production applications. Each system is designed to automate the critical aseptic operations for vial, syringe and cartridge processing to reduce contamination risk and product variability. These table-top systems are engineered to have complete compatibility with cleanroom environments, including Laminar Air Flow Hoods, Bio-Safety Cabinets and aseptic isolators.

AST’s Container Closing System (CCS) is a benchtop, semi-automatic machine that provides complete and accurate control of the syringe and cartridge closing process. The Container Closing System is able to close syringes or cartridges using both vacuum and vent-tube methods for a wide range of container sizes quickly and easily with only a few format part changes.

AST’s Container Filling System (CFS) is a bench-top, semi-automatic machine used for the filling of pre-filled syringes and cartridges, and the filling and stoppering of vials and bottles. The system is designed to meet the demanding requirements for small batch processing of sterile injectable products.

AST's Vial Sealing System (VSS) is a benchtop, semi-automatic machine used for sealing or capping pharmaceutical vials and bottles with aluminum caps. The VSS provides complete and precise control of the container sealing or capping operations to ensure the highest quality vial seal. The system’s versatility allows for the processing of a wide range of vial or bottle sizes and finishes and is ideal for small batch processing of sterile pharmaceutical and biotechnology products.

CONTACT INFORMATION

Automated Systems of Tacoma, Inc.

4110 South Washington Street

Tacoma, WA 98409

UNITED STATES

Phone: 253-475-0200

Contact: Brittany Hoff

FEATURED ARTICLES

AST VIDEOS

  • The Use Of Robotics In Small-Scale Aseptic Fill-Finish Operations

    This presentation addresses the changing needs for the manufacturing of biologics and the rationale for the use of robotics and automation in aseptic fill and finish processing of these products. The webinar covers industry drivers and manufacturing challenges for biologics and provides an introduction to both robots and the specific advantages they provide.

  • ASEPTiCell® Robotic Filling And Finishing

    AST’s ASEPTiCell® provides flexible, robotic filling and finishing of vials, syringes and cartridges for small to medium clinical and commercial batches. AST’s modular design allows the ASEPTiCell to be built to your specification without the cost and risk of customization.

  • GENiSYS® R Robotic Handling

    The GENiSYS® R offers a unique blend of automated capabilities to ensure your sterile products are processed in strict accordance with cGMP requirements. With robotic handling available from bag opening to vial sealing, and integration with barrier technologies, your product is protected from contamination through all stages of processing. 

  • Maximize Productivity With The GENiSYS® R

    GENiSYS® R provides ultimate flexibility for processing ready-to-use vials, syringes and cartridges on a single machine. Highly reliable robotics and recipe driven changeovers allow for complete format changes in as little as 30 minutes. Maximize productivity and return-on-investment with the GENiSYS R.

  • GENiSYS® Lab Semi-Automatic Systems

    AST’s GENiSYS® Lab semi-automatic systems are ideal for drug product development and cGMP production applications. Each system automates the critical aseptic operations for vial, syringe and cartridge processing to reduce contamination risk and product variability. GENiSYS Lab offers a perfect balance between automated features, size and affordability without compromising quality, safety and ease of use.

  • How Robotics Offer Answers To Today’s Pharmaceutical Manufacturing Challenges

    What are the COVID-19 effects on pharmaceutical manufacturing? Can we expect “onshoring” strategies following the crisis? Is the general opinion about robotics improving? Watch this webinar to learn more about where and how robotics add value and solve problems.