Development & Manufacturing White Papers & Case Studies

1. Solid-State Characterization Of A Small Molecule API 4/10/2024

   Ensuring the consistency and purity of the API is paramount when developing a new drug. Learn about the importance of CRO partnerships when facing tight deadlines and complex scientific hurdles.

2. Liquids, Soft Foods As Vehicles For Enteric Coated Bead Drug Product 4/10/2024

   Take a deeper look at the challenges and solutions involved in creating a child-friendly medication delivery system, and learn about the importance of collaboration and meticulous scientific processes.

3. A Better Immune Response To Vaccination: Using Lymphoid Follicle Organ-Chips 4/9/2024

   Discover a first-of-its-kind human LF-Chip containing B, T, plasma and antigen-presenting cells to test functional immunization responses to vaccines and adjuvants in vitro.

4. Creating An Effective Pre-Clinical Model Of Bone Marrow 4/9/2024

   A Bone Marrow-Chip (BM-Chip) was created to recapitulate relevant hematopoietic cell types in a three-dimensional (3D), mechanically active next-generation in vitro model.

5. Revolutionizing Viral Infectious Disease Research And Drug Discovery 4/8/2024

   Learn how Organ-Chips are being used to rapidly identify promising treatments, investigate virus evolution, and analyze how mechanical forces influence the innate immune response to viral infections.

6. Manufacturing Challenges With High Concentration Biologics 3/18/2024

   Explore key process operations, some of the challenges in manufacturing high-concentration biologics, and factors to consider for process optimization.

7. Frontage Takes The First Step In Creating Their Intelligent Laboratory 3/15/2024

   Learn how the implementation of a lab management system has enabled Frontage to accelerate its operations and initiate its journey toward establishing a truly intelligent laboratory.

8. Proximal Tubule Kidney-Chip For Modeling Human Physiology 3/14/2024

   Discover how an Organ-Chip can be used to create a comprehensive recapitulation of the proximal tubule, addressing the need for more human-relevant preclinical models in the pharmaceutical industry.

9. Duodenum Intestine-Chip For Modeling Human Physiology 3/14/2024

   Discover an Intestine-Chip that integrates the robust cell sourcing of organoids with Organs-on-Chips technology to overcome experimental limitations and yield a closer-to-human transcriptomic profile.

10. Development And Characterization Of The Species-Specific Liver-Chip 3/14/2024

    There is a growing need for more human-relevant preclinical models. Explore how Organ-Chips offer a viable solution and can be used to create a comprehensive recapitulation of the liver sinusoid.