This latest evolution of HVLD aims to achieve a high level of closed container integrity (CCI) assurance across the entire range of parenteral products.
A&Z Pharmaceutical improved their production efficiencies, selecting an unusual chute-fed checkweigher, which helps ensure final product quality, reduce labor and speed production.
Metal detector sensitivity performance is usually expressed in terms of the diameter of a test sphere made from a specific type of metal, such as ferrous, non-ferrous, aluminum or stainless steel.
A typical batch fermentation process starts with sterilization so that all micro-organisms found in the mash and reactor are completely destroyed. The mash is heated in the fermenter or a special cooking vessel by injecting live steam or by means of steam coils set in the vessel. Holding the temperature at 121°C (250°F) for 30 minutes is usually adequate to destroy all living organisms in the mash. However some processes require higher temperatures. As shown in Figure 1, a heating/cooling jacket maintains the temperature of the fermentor.
Biopharmaceutical Chromatography Systems are designed for separating and purifying proteins and bio-engineered products. Flow systems are compact in design to maximize throughput. No dead legs in process pipe can exist since unswept areas are more challenging to completely clean as well as delaying product throughput. The systems must maintain a hygienic design. Wetted surface finish must be < 20 μinch Ra and material traceability is important to maintain system integrity.
A major multinational pharmaceutical company determined that pH maintenance accounts for 46% of all the field work. Customer wanted to increase pH reliability and eliminate rework/scrap due to poor pH measurements. They also wanted to streamline maintenance practices.
Planning and implementing good investments requires well-planned strategies, decision-makers who know their goals, and carrying out the implementation according to plan. Meaningful information forms the basis of a good investment decision and it helps to protect the future prosperity of your company. This white paper will help you answer several question regarding the total cost of ownership (TCO) of production line equipment including, "have you clarified the foundations of your investment decisions?" and "how do you determine and calculate the return on investment (ROI) time of an investment?"