Application Notes & Case Studies
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Optimize T Cell Phenotype With One-Step Isolation And Activation
5/10/2024
This comparative bench-scale study features active-release beads that could improve the reliability, consistency, and longevity of cell therapy treatments.
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A New Era Of Intuitive Simplicity In HPLC
5/10/2024
Explore specific use cases of the Waters Alliance iS HPLC System, including common pharmaceutical QC applications, method migration from legacy HPLC systems, and more.
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A Transient Cell Line To Produce rAAV With Low-Level hcDNA Encapsidation
5/10/2024
Discover the ability of a novel HEK293 suspension cell line for efficient and scalable rAAV production across various serotypes with low encapsidated host cell DNA levels.
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Explore A High-Performing Basal Medium And Feed Pairing
5/8/2024
A customer sought to replace a chemically defined CHO medium with a more efficient medium and feed pairing strategy in bioreactors.
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Advancing Cell Therapy Manufacturing: Rapid Sterility Testing
5/7/2024
The rapid sterility test kit used in the study was able to quickly detect bacteria and fungi in complex cell therapy product matrices, detecting six species listed in USP chapter <71>.
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Review Of Applications And Processes In Fixed-Bed Bioreactors
5/6/2024
Gain insights and guidelines for developing new processes in this review evaluating publications on the applications of single-use, scalable fixed-bed bioreactors for adherent cell culture processes.
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Lentiviral Vector Production Using Single-Use Bioreactors
5/6/2024
Here, we outline a scalable and robust upstream process developed for LVV production of HEK293T cells and demonstrate how to expand HEK293T suspension cells.
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Expansion Of Specific Lymphocytes With A Xeno-Free, Serum-Free Medium
4/29/2024
Explore the advantages of utilizing a xeno- and serum-free medium for the targeted expansion of cell subpopulations without the addition of serum.
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Streamlined Facility Design: A Success Story
4/29/2024
Examine how one medium-sized US company's need for a new aseptic compounding and fill-finish facility was addressed with a tailored solution within a challenging time-frame.
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Accelerating SARS-CoV-2 Immunotherapy Speed To Clinic
4/26/2024
A clinical-stage biotherapeutics company developing a COVID-19 immunotherapy searched for a solution to the difficulties it faced in scaling up its manufacturing operations due to limited resources.