Articles
RSSRelease Modifying Potential Of EUDRAGIT® RS, RL And EUDRAGIT® NE 30 D In Multi-Particulate Systems
January 5, 2010
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•Poster: Release Modifying Potential Of EUDRAGIT® RS, RL And EUDRAGIT® NE 30 D In Multi-Particulate Systems
•Poster: Release Modifying Potential Of EUDRAGIT® RS, RL And EUDRAGIT® NE 30 D In Multi-Particulate Systems
•Poster: Release Modifying Potential Of EUDRAGIT® RS, RL And EUDRAGIT® NE 30 D In Multi-Particulate Systems
By Evonik Röhm GmbH
Although multi-unit systems are more complicated to formulate and manufacture, they provide many advantages over single-unit modified release systems. Few of the advantages offered by multi-particulate dosage forms are:
- lower intra and inter individual variability in plasma levels
- lower tendency for local irritation as the drug is more widely distributed in the GI tract
The objective of this study was to demonstrate versatility of EUDRAGIT® NE, RS and RL as matrix forming agents in multi-particulate applications. Theophylline and acetaminophen were selected as model API for the study owing to their moderate to high solubility in water.
Click Here To Download:•Poster: Release Modifying Potential Of EUDRAGIT® RS, RL And EUDRAGIT® NE 30 D In Multi-Particulate Systems
